| Full name: oxysterol binding protein like 3 | Alias Symbol: ORP-3|ORP3|KIAA0704 | ||
| Type: protein-coding gene | Cytoband: 7p15.3 | ||
| Entrez ID: 26031 | HGNC ID: HGNC:16370 | Ensembl Gene: ENSG00000070882 | OMIM ID: 606732 |
| Drug and gene relationship at DGIdb | |||
Expression of OSBPL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSBPL3 | 26031 | 209626_s_at | 0.4766 | 0.4568 | |
| GSE20347 | OSBPL3 | 26031 | 209627_s_at | 0.1432 | 0.5645 | |
| GSE23400 | OSBPL3 | 26031 | 209627_s_at | 0.2522 | 0.0052 | |
| GSE26886 | OSBPL3 | 26031 | 209626_s_at | -0.3024 | 0.4001 | |
| GSE29001 | OSBPL3 | 26031 | 209626_s_at | 0.4851 | 0.2136 | |
| GSE38129 | OSBPL3 | 26031 | 209627_s_at | 0.4483 | 0.0194 | |
| GSE45670 | OSBPL3 | 26031 | 209626_s_at | 0.7178 | 0.0013 | |
| GSE53622 | OSBPL3 | 26031 | 39719 | 0.5788 | 0.0000 | |
| GSE53624 | OSBPL3 | 26031 | 39719 | 0.5429 | 0.0000 | |
| GSE63941 | OSBPL3 | 26031 | 209626_s_at | 1.0210 | 0.1097 | |
| GSE77861 | OSBPL3 | 26031 | 209626_s_at | 0.2644 | 0.5621 | |
| GSE97050 | OSBPL3 | 26031 | A_23_P215525 | 1.0319 | 0.1616 | |
| SRP007169 | OSBPL3 | 26031 | RNAseq | -0.1435 | 0.7716 | |
| SRP008496 | OSBPL3 | 26031 | RNAseq | 0.1667 | 0.6367 | |
| SRP064894 | OSBPL3 | 26031 | RNAseq | 0.1228 | 0.6647 | |
| SRP133303 | OSBPL3 | 26031 | RNAseq | 0.3217 | 0.0417 | |
| SRP159526 | OSBPL3 | 26031 | RNAseq | -0.1369 | 0.4299 | |
| SRP193095 | OSBPL3 | 26031 | RNAseq | 0.0952 | 0.3975 | |
| SRP219564 | OSBPL3 | 26031 | RNAseq | 0.0416 | 0.9482 | |
| TCGA | OSBPL3 | 26031 | RNAseq | 0.1525 | 0.0309 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OSBPL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSBPL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSBPL3 | 26031 | 17 | 1 | 12 | |
| GSE20123 | OSBPL3 | 26031 | 17 | 1 | 12 | |
| GSE43470 | OSBPL3 | 26031 | 4 | 0 | 39 | |
| GSE46452 | OSBPL3 | 26031 | 10 | 2 | 47 | |
| GSE47630 | OSBPL3 | 26031 | 9 | 1 | 30 | |
| GSE54993 | OSBPL3 | 26031 | 0 | 6 | 64 | |
| GSE54994 | OSBPL3 | 26031 | 21 | 2 | 30 | |
| GSE60625 | OSBPL3 | 26031 | 0 | 0 | 11 | |
| GSE74703 | OSBPL3 | 26031 | 4 | 0 | 32 | |
| GSE74704 | OSBPL3 | 26031 | 11 | 1 | 8 | |
| TCGA | OSBPL3 | 26031 | 56 | 5 | 35 |
Total number of gains: 149; Total number of losses: 19; Total Number of normals: 320.
Somatic mutations of OSBPL3:
Generating mutation plots.
Highly correlated genes for OSBPL3:
Showing top 20/290 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSBPL3 | NUDT5 | 0.739831 | 3 | 0 | 3 |
| OSBPL3 | WNT10A | 0.715036 | 3 | 0 | 3 |
| OSBPL3 | SOD2 | 0.711845 | 3 | 0 | 3 |
| OSBPL3 | PIGW | 0.710003 | 3 | 0 | 3 |
| OSBPL3 | PODNL1 | 0.709174 | 4 | 0 | 4 |
| OSBPL3 | LACTB | 0.700654 | 3 | 0 | 3 |
| OSBPL3 | TLCD1 | 0.699156 | 3 | 0 | 3 |
| OSBPL3 | PIGG | 0.693745 | 3 | 0 | 3 |
| OSBPL3 | AJUBA | 0.682755 | 4 | 0 | 3 |
| OSBPL3 | GSR | 0.682245 | 3 | 0 | 3 |
| OSBPL3 | LYAR | 0.675028 | 3 | 0 | 3 |
| OSBPL3 | CD47 | 0.67402 | 4 | 0 | 3 |
| OSBPL3 | SP140 | 0.671241 | 3 | 0 | 3 |
| OSBPL3 | MATN3 | 0.667301 | 3 | 0 | 3 |
| OSBPL3 | SCARB1 | 0.665416 | 3 | 0 | 3 |
| OSBPL3 | GTF2E2 | 0.661755 | 3 | 0 | 3 |
| OSBPL3 | ARNTL2 | 0.653228 | 3 | 0 | 3 |
| OSBPL3 | IGF2BP2 | 0.652778 | 4 | 0 | 4 |
| OSBPL3 | KIAA0930 | 0.651874 | 5 | 0 | 4 |
| OSBPL3 | TRMT1 | 0.648339 | 4 | 0 | 4 |
For details and further investigation, click here
