| Full name: aryl hydrocarbon receptor nuclear translocator like 2 | Alias Symbol: BMAL2|MOP9|CLIF|PASD9|bHLHe6 | ||
| Type: protein-coding gene | Cytoband: 12p11.23 | ||
| Entrez ID: 56938 | HGNC ID: HGNC:18984 | Ensembl Gene: ENSG00000029153 | OMIM ID: 614517 |
| Drug and gene relationship at DGIdb | |||
Expression of ARNTL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARNTL2 | 56938 | 224204_x_at | -0.2133 | 0.9264 | |
| GSE20347 | ARNTL2 | 56938 | 220658_s_at | -1.5096 | 0.0000 | |
| GSE23400 | ARNTL2 | 56938 | 220658_s_at | -1.0753 | 0.0000 | |
| GSE26886 | ARNTL2 | 56938 | 224204_x_at | -1.9582 | 0.0000 | |
| GSE29001 | ARNTL2 | 56938 | 220658_s_at | -1.6950 | 0.0080 | |
| GSE38129 | ARNTL2 | 56938 | 220658_s_at | -0.6373 | 0.2204 | |
| GSE45670 | ARNTL2 | 56938 | 220658_s_at | 0.1216 | 0.7045 | |
| GSE53622 | ARNTL2 | 56938 | 9247 | -0.1169 | 0.6358 | |
| GSE53624 | ARNTL2 | 56938 | 9247 | -1.1017 | 0.0000 | |
| GSE63941 | ARNTL2 | 56938 | 223586_at | 0.9146 | 0.4561 | |
| GSE77861 | ARNTL2 | 56938 | 224204_x_at | -0.5010 | 0.1939 | |
| GSE97050 | ARNTL2 | 56938 | A_23_P53345 | 1.0781 | 0.3373 | |
| SRP007169 | ARNTL2 | 56938 | RNAseq | -1.5458 | 0.0001 | |
| SRP008496 | ARNTL2 | 56938 | RNAseq | -1.0419 | 0.0017 | |
| SRP064894 | ARNTL2 | 56938 | RNAseq | -1.5336 | 0.0000 | |
| SRP133303 | ARNTL2 | 56938 | RNAseq | 0.3492 | 0.2789 | |
| SRP159526 | ARNTL2 | 56938 | RNAseq | -1.1040 | 0.0356 | |
| SRP193095 | ARNTL2 | 56938 | RNAseq | 0.0012 | 0.9965 | |
| SRP219564 | ARNTL2 | 56938 | RNAseq | -1.0580 | 0.1866 | |
| TCGA | ARNTL2 | 56938 | RNAseq | 0.4952 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by ARNTL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARNTL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARNTL2 | 56938 | 10 | 1 | 19 | |
| GSE20123 | ARNTL2 | 56938 | 10 | 1 | 19 | |
| GSE43470 | ARNTL2 | 56938 | 10 | 4 | 29 | |
| GSE46452 | ARNTL2 | 56938 | 10 | 1 | 48 | |
| GSE47630 | ARNTL2 | 56938 | 14 | 0 | 26 | |
| GSE54993 | ARNTL2 | 56938 | 0 | 9 | 61 | |
| GSE54994 | ARNTL2 | 56938 | 10 | 2 | 41 | |
| GSE60625 | ARNTL2 | 56938 | 0 | 1 | 10 | |
| GSE74703 | ARNTL2 | 56938 | 9 | 3 | 24 | |
| GSE74704 | ARNTL2 | 56938 | 5 | 1 | 14 | |
| TCGA | ARNTL2 | 56938 | 44 | 6 | 46 |
Total number of gains: 122; Total number of losses: 29; Total Number of normals: 337.
Somatic mutations of ARNTL2:
Generating mutation plots.
Highly correlated genes for ARNTL2:
Showing top 20/1174 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARNTL2 | E2F2 | 0.773601 | 3 | 0 | 3 |
| ARNTL2 | HPSE | 0.766802 | 11 | 0 | 11 |
| ARNTL2 | ORMDL2 | 0.743803 | 8 | 0 | 8 |
| ARNTL2 | ELOVL1 | 0.743762 | 3 | 0 | 3 |
| ARNTL2 | F2RL1 | 0.74167 | 3 | 0 | 3 |
| ARNTL2 | MREG | 0.732508 | 10 | 0 | 9 |
| ARNTL2 | SORD | 0.730537 | 3 | 0 | 3 |
| ARNTL2 | GJB2 | 0.730311 | 4 | 0 | 3 |
| ARNTL2 | KRT80 | 0.73029 | 6 | 0 | 6 |
| ARNTL2 | PLIN3 | 0.730141 | 11 | 0 | 11 |
| ARNTL2 | PRDM1 | 0.720632 | 11 | 0 | 11 |
| ARNTL2 | NUAK2 | 0.716669 | 3 | 0 | 3 |
| ARNTL2 | XG | 0.712781 | 6 | 0 | 6 |
| ARNTL2 | SH2D3A | 0.710626 | 8 | 0 | 7 |
| ARNTL2 | TMOD3 | 0.710615 | 10 | 0 | 9 |
| ARNTL2 | TMPRSS11E | 0.707426 | 9 | 0 | 9 |
| ARNTL2 | IL36RN | 0.707011 | 10 | 0 | 10 |
| ARNTL2 | HMOX2 | 0.7068 | 11 | 0 | 11 |
| ARNTL2 | DSG3 | 0.706078 | 10 | 0 | 10 |
| ARNTL2 | JUP | 0.705706 | 9 | 0 | 9 |
For details and further investigation, click here
