| Full name: leucine rich repeat containing 59 | Alias Symbol: PRO1855|FLJ21675 | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 55379 | HGNC ID: HGNC:28817 | Ensembl Gene: ENSG00000108829 | OMIM ID: 614854 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC59:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC59 | 55379 | 222231_s_at | 0.5367 | 0.3270 | |
| GSE20347 | LRRC59 | 55379 | 222231_s_at | 0.2932 | 0.0927 | |
| GSE23400 | LRRC59 | 55379 | 222231_s_at | 0.7405 | 0.0000 | |
| GSE26886 | LRRC59 | 55379 | 222231_s_at | 0.3619 | 0.0668 | |
| GSE29001 | LRRC59 | 55379 | 222231_s_at | 0.2896 | 0.3902 | |
| GSE38129 | LRRC59 | 55379 | 222231_s_at | 0.6751 | 0.0000 | |
| GSE45670 | LRRC59 | 55379 | 222231_s_at | 0.5267 | 0.0137 | |
| GSE63941 | LRRC59 | 55379 | 222231_s_at | -0.0180 | 0.9677 | |
| GSE77861 | LRRC59 | 55379 | 222231_s_at | 0.6679 | 0.0003 | |
| GSE97050 | LRRC59 | 55379 | A_24_P181585 | 0.7288 | 0.1453 | |
| SRP007169 | LRRC59 | 55379 | RNAseq | 1.1468 | 0.0029 | |
| SRP008496 | LRRC59 | 55379 | RNAseq | 0.8408 | 0.0010 | |
| SRP064894 | LRRC59 | 55379 | RNAseq | 0.7558 | 0.0000 | |
| SRP133303 | LRRC59 | 55379 | RNAseq | 1.2695 | 0.0000 | |
| SRP159526 | LRRC59 | 55379 | RNAseq | 0.6500 | 0.0186 | |
| SRP193095 | LRRC59 | 55379 | RNAseq | 0.3100 | 0.1004 | |
| SRP219564 | LRRC59 | 55379 | RNAseq | 1.0621 | 0.0205 | |
| TCGA | LRRC59 | 55379 | RNAseq | -0.0308 | 0.5142 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LRRC59 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LRRC59:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC59 | 55379 | 5 | 2 | 23 | |
| GSE20123 | LRRC59 | 55379 | 5 | 2 | 23 | |
| GSE43470 | LRRC59 | 55379 | 3 | 2 | 38 | |
| GSE46452 | LRRC59 | 55379 | 32 | 0 | 27 | |
| GSE47630 | LRRC59 | 55379 | 9 | 0 | 31 | |
| GSE54993 | LRRC59 | 55379 | 2 | 4 | 64 | |
| GSE54994 | LRRC59 | 55379 | 9 | 6 | 38 | |
| GSE60625 | LRRC59 | 55379 | 4 | 0 | 7 | |
| GSE74703 | LRRC59 | 55379 | 3 | 2 | 31 | |
| GSE74704 | LRRC59 | 55379 | 4 | 1 | 15 | |
| TCGA | LRRC59 | 55379 | 27 | 7 | 62 |
Total number of gains: 103; Total number of losses: 26; Total Number of normals: 359.
Somatic mutations of LRRC59:
Generating mutation plots.
Highly correlated genes for LRRC59:
Showing top 20/1647 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC59 | DIP2B | 0.811034 | 3 | 0 | 3 |
| LRRC59 | HAS3 | 0.774878 | 4 | 0 | 4 |
| LRRC59 | EFTUD2 | 0.769831 | 5 | 0 | 5 |
| LRRC59 | DPYSL2 | 0.769337 | 3 | 0 | 3 |
| LRRC59 | GLRX3 | 0.760688 | 8 | 0 | 8 |
| LRRC59 | ITGB8 | 0.760672 | 3 | 0 | 3 |
| LRRC59 | SDHAF2 | 0.760058 | 4 | 0 | 3 |
| LRRC59 | EME1 | 0.759708 | 5 | 0 | 5 |
| LRRC59 | TOP1MT | 0.759587 | 3 | 0 | 3 |
| LRRC59 | DCAF13 | 0.756524 | 3 | 0 | 3 |
| LRRC59 | NOL11 | 0.752647 | 9 | 0 | 9 |
| LRRC59 | SPRED1 | 0.75256 | 4 | 0 | 4 |
| LRRC59 | DDX55 | 0.750207 | 3 | 0 | 3 |
| LRRC59 | NUDCD1 | 0.748171 | 3 | 0 | 3 |
| LRRC59 | ABCA12 | 0.747105 | 4 | 0 | 4 |
| LRRC59 | TCF19 | 0.745999 | 3 | 0 | 3 |
| LRRC59 | PSMD12 | 0.745878 | 8 | 0 | 8 |
| LRRC59 | TMEM208 | 0.74342 | 8 | 0 | 8 |
| LRRC59 | RANBP1 | 0.7395 | 8 | 0 | 8 |
| LRRC59 | DCBLD1 | 0.737967 | 5 | 0 | 5 |
For details and further investigation, click here
