ATP13A3

 

Full name: ATPase 13A3 Alias Symbol: AFURS1
Type: protein-coding gene Cytoband: 3q29
Entrez ID: 79572 HGNC ID: HGNC:24113 Ensembl Gene: ENSG00000133657 OMIM ID: 610232
Drug and gene relationship at DGIdb

 

Expression of ATP13A3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ATP13A3 79572 212297_at 1.1831 0.0355
GSE20347 ATP13A3 79572 212297_at 0.9755 0.0000
GSE23400 ATP13A3 79572 212297_at 0.7902 0.0000
GSE26886 ATP13A3 79572 212297_at 0.8150 0.0079
GSE29001 ATP13A3 79572 212297_at 0.8100 0.0002
GSE38129 ATP13A3 79572 212297_at 1.0272 0.0000
GSE45670 ATP13A3 79572 212297_at 0.9104 0.0002
GSE53622 ATP13A3 79572 91433 0.9452 0.0000
GSE53624 ATP13A3 79572 16750 0.8031 0.0000
GSE63941 ATP13A3 79572 212297_at -0.7624 0.1115
GSE77861 ATP13A3 79572 212297_at 1.0410 0.0020
GSE97050 ATP13A3 79572 A_33_P3225327 1.4051 0.1146
SRP007169 ATP13A3 79572 RNAseq 1.1003 0.0010
SRP008496 ATP13A3 79572 RNAseq 1.2296 0.0000
SRP064894 ATP13A3 79572 RNAseq 1.0525 0.0013
SRP133303 ATP13A3 79572 RNAseq 1.5478 0.0000
SRP159526 ATP13A3 79572 RNAseq 1.1287 0.0015
SRP193095 ATP13A3 79572 RNAseq 1.0483 0.0000
SRP219564 ATP13A3 79572 RNAseq 0.6131 0.2141
TCGA ATP13A3 79572 RNAseq 0.1544 0.0014

Upregulated datasets: 9; Downregulated datasets: 0.  

 

Survival by ATP13A3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ATP13A3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ATP13A3 79572 22 0 8
GSE20123 ATP13A3 79572 22 0 8
GSE43470 ATP13A3 79572 24 0 19
GSE46452 ATP13A3 79572 19 1 39
GSE47630 ATP13A3 79572 27 2 11
GSE54993 ATP13A3 79572 1 21 48
GSE54994 ATP13A3 79572 41 0 12
GSE60625 ATP13A3 79572 0 6 5
GSE74703 ATP13A3 79572 20 0 16
GSE74704 ATP13A3 79572 14 0 6
TCGA ATP13A3 79572 77 0 19

Total number of gains: 267; Total number of losses: 30; Total Number of normals: 191.  

 

Somatic mutations of ATP13A3:

 

Generating mutation plots.

 

Highly correlated genes for ATP13A3:

 

Showing top 20/1822 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ATP13A3ACTL6A0.80977811011
ATP13A3CDCA20.809423505
ATP13A3KPNA20.787642909
ATP13A3MRPL470.778789707
ATP13A3AURKA0.77217411011
ATP13A3TRIP130.76958411011
ATP13A3XPOT0.76589910010
ATP13A3KIF140.7651911011
ATP13A3RFC40.76418611011
ATP13A3PSMD20.76081110010
ATP13A3CEP550.76005111010
ATP13A3SNRPG0.7599211011
ATP13A3GMPS0.75906711011
ATP13A3ANKRD13C0.756983303
ATP13A3ECT20.75691811010
ATP13A3CBX30.75682910010
ATP13A3FAM89A0.756054303
ATP13A3TFRC0.75489611011
ATP13A3ORC60.74977210010
ATP13A3ALKBH60.749524404

For details and further investigation, click here