| Full name: EH domain containing 1 | Alias Symbol: H-PAST|HPAST1|FLJ42622|FLJ44618 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 10938 | HGNC ID: HGNC:3242 | Ensembl Gene: ENSG00000110047 | OMIM ID: 605888 |
| Drug and gene relationship at DGIdb | |||
Expression of EHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EHD1 | 10938 | 209039_x_at | 0.3751 | 0.1635 | |
| GSE20347 | EHD1 | 10938 | 209039_x_at | -0.0194 | 0.8821 | |
| GSE23400 | EHD1 | 10938 | 208112_x_at | -0.2294 | 0.0011 | |
| GSE26886 | EHD1 | 10938 | 208112_x_at | -0.0695 | 0.7797 | |
| GSE29001 | EHD1 | 10938 | 209039_x_at | -0.1647 | 0.4464 | |
| GSE38129 | EHD1 | 10938 | 209039_x_at | -0.3822 | 0.0121 | |
| GSE45670 | EHD1 | 10938 | 208112_x_at | -0.0001 | 0.9998 | |
| GSE53622 | EHD1 | 10938 | 6147 | -0.0678 | 0.4732 | |
| GSE53624 | EHD1 | 10938 | 6147 | 0.1737 | 0.0082 | |
| GSE63941 | EHD1 | 10938 | 208112_x_at | 0.1036 | 0.8712 | |
| GSE77861 | EHD1 | 10938 | 208112_x_at | -0.0024 | 0.9853 | |
| GSE97050 | EHD1 | 10938 | A_23_P52647 | -0.1969 | 0.4819 | |
| SRP007169 | EHD1 | 10938 | RNAseq | -1.5501 | 0.0073 | |
| SRP008496 | EHD1 | 10938 | RNAseq | -1.3723 | 0.0000 | |
| SRP064894 | EHD1 | 10938 | RNAseq | -0.3647 | 0.1209 | |
| SRP133303 | EHD1 | 10938 | RNAseq | 0.1060 | 0.6730 | |
| SRP159526 | EHD1 | 10938 | RNAseq | -0.9693 | 0.0000 | |
| SRP193095 | EHD1 | 10938 | RNAseq | 0.1695 | 0.4671 | |
| SRP219564 | EHD1 | 10938 | RNAseq | -0.2137 | 0.6621 | |
| TCGA | EHD1 | 10938 | RNAseq | -0.1090 | 0.0571 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by EHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EHD1 | 10938 | 7 | 6 | 17 | |
| GSE20123 | EHD1 | 10938 | 7 | 6 | 17 | |
| GSE43470 | EHD1 | 10938 | 1 | 3 | 39 | |
| GSE46452 | EHD1 | 10938 | 10 | 4 | 45 | |
| GSE47630 | EHD1 | 10938 | 5 | 6 | 29 | |
| GSE54993 | EHD1 | 10938 | 3 | 0 | 67 | |
| GSE54994 | EHD1 | 10938 | 6 | 5 | 42 | |
| GSE60625 | EHD1 | 10938 | 0 | 3 | 8 | |
| GSE74703 | EHD1 | 10938 | 1 | 1 | 34 | |
| GSE74704 | EHD1 | 10938 | 5 | 4 | 11 | |
| TCGA | EHD1 | 10938 | 23 | 7 | 66 |
Total number of gains: 68; Total number of losses: 45; Total Number of normals: 375.
Somatic mutations of EHD1:
Generating mutation plots.
Highly correlated genes for EHD1:
Showing top 20/289 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EHD1 | C12orf65 | 0.76749 | 3 | 0 | 3 |
| EHD1 | PIGX | 0.743355 | 3 | 0 | 3 |
| EHD1 | KIF3C | 0.73405 | 3 | 0 | 3 |
| EHD1 | NUDT4 | 0.730494 | 3 | 0 | 3 |
| EHD1 | SLC4A5 | 0.728079 | 3 | 0 | 3 |
| EHD1 | DENND5B | 0.727431 | 3 | 0 | 3 |
| EHD1 | TNFRSF1A | 0.723914 | 3 | 0 | 3 |
| EHD1 | PHKG2 | 0.719451 | 3 | 0 | 3 |
| EHD1 | SORBS3 | 0.714572 | 4 | 0 | 4 |
| EHD1 | MSN | 0.712546 | 3 | 0 | 3 |
| EHD1 | ZCCHC17 | 0.710035 | 3 | 0 | 3 |
| EHD1 | CXXC1 | 0.704162 | 4 | 0 | 4 |
| EHD1 | MAPRE3 | 0.696518 | 3 | 0 | 3 |
| EHD1 | MCAM | 0.694468 | 4 | 0 | 4 |
| EHD1 | RAB13 | 0.692493 | 3 | 0 | 3 |
| EHD1 | FAM193A | 0.689449 | 4 | 0 | 3 |
| EHD1 | MTHFR | 0.686289 | 4 | 0 | 4 |
| EHD1 | TNP2 | 0.681196 | 4 | 0 | 4 |
| EHD1 | BARHL1 | 0.680485 | 3 | 0 | 3 |
| EHD1 | SEMA3A | 0.678962 | 3 | 0 | 3 |
For details and further investigation, click here
