PLIN2

 

Full name: perilipin 2 Alias Symbol: ADRP
Type: protein-coding gene Cytoband: 9p22.1
Entrez ID: 123 HGNC ID: HGNC:248 Ensembl Gene: ENSG00000147872 OMIM ID: 103195
Drug and gene relationship at DGIdb

 

Expression of PLIN2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PLIN2 123 209122_at 0.3668 0.7704
GSE20347 PLIN2 123 209122_at 0.6339 0.0166
GSE23400 PLIN2 123 209122_at 0.3863 0.0038
GSE26886 PLIN2 123 209122_at -0.1654 0.8023
GSE29001 PLIN2 123 209122_at 0.3876 0.4087
GSE38129 PLIN2 123 209122_at 0.4155 0.2034
GSE45670 PLIN2 123 209122_at -0.4824 0.3770
GSE53622 PLIN2 123 6350 0.2867 0.0399
GSE53624 PLIN2 123 6350 0.3786 0.0027
GSE63941 PLIN2 123 209122_at -4.3766 0.0048
GSE77861 PLIN2 123 209122_at -0.3751 0.2872
GSE97050 PLIN2 123 A_23_P134953 0.6275 0.1678
SRP007169 PLIN2 123 RNAseq 1.4056 0.0547
SRP008496 PLIN2 123 RNAseq 1.4881 0.0025
SRP064894 PLIN2 123 RNAseq 0.9930 0.0004
SRP133303 PLIN2 123 RNAseq 0.6943 0.1020
SRP159526 PLIN2 123 RNAseq 0.1438 0.6857
SRP193095 PLIN2 123 RNAseq 0.9550 0.0045
SRP219564 PLIN2 123 RNAseq 0.5501 0.1780
TCGA PLIN2 123 RNAseq -0.2198 0.1042

Upregulated datasets: 1; Downregulated datasets: 1.  

 

Survival by PLIN2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PLIN2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PLIN2 123 2 16 12
GSE20123 PLIN2 123 2 16 12
GSE43470 PLIN2 123 5 11 27
GSE46452 PLIN2 123 2 23 34
GSE47630 PLIN2 123 3 27 10
GSE54993 PLIN2 123 6 2 62
GSE54994 PLIN2 123 7 18 28
GSE60625 PLIN2 123 0 0 11
GSE74703 PLIN2 123 5 8 23
GSE74704 PLIN2 123 0 13 7
TCGA PLIN2 123 12 51 33

Total number of gains: 44; Total number of losses: 185; Total Number of normals: 259.  

 

Somatic mutations of PLIN2:

 

Generating mutation plots.

 

Highly correlated genes for PLIN2:

 

Showing top 20/366 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PLIN2ATP11C0.817535303
PLIN2ANKRD440.769692303
PLIN2PPIP5K20.756545303
PLIN2ERGIC30.746702303
PLIN2LYSMD30.745679303
PLIN2ARPC50.73399303
PLIN2CTTNBP2NL0.72933303
PLIN2BRK10.727893303
PLIN2FBXL30.723203303
PLIN2TMEM50A0.719903303
PLIN2STXBP40.718298303
PLIN2A1BG0.713229303
PLIN2ZFYVE160.712648303
PLIN2CLP10.711269303
PLIN2ATXN10.710113303
PLIN2GNS0.7079403
PLIN2ARHGAP170.704898303
PLIN2ZNF4320.694084303
PLIN2STXBP50.690254303
PLIN2SUSD10.688638303

For details and further investigation, click here