| Full name: Rho GTPase activating protein 17 | Alias Symbol: RICH1|FLJ10308|NADRIN|FLJ13219|WBP15 | ||
| Type: protein-coding gene | Cytoband: 16p12.1 | ||
| Entrez ID: 55114 | HGNC ID: HGNC:18239 | Ensembl Gene: ENSG00000140750 | OMIM ID: 608293 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP17 | 55114 | 218076_s_at | 0.0037 | 0.9948 | |
| GSE20347 | ARHGAP17 | 55114 | 218076_s_at | -0.1942 | 0.0457 | |
| GSE23400 | ARHGAP17 | 55114 | 218076_s_at | -0.0867 | 0.0864 | |
| GSE26886 | ARHGAP17 | 55114 | 218076_s_at | -0.6391 | 0.0003 | |
| GSE29001 | ARHGAP17 | 55114 | 218076_s_at | -0.4445 | 0.0081 | |
| GSE38129 | ARHGAP17 | 55114 | 218076_s_at | -0.2372 | 0.1258 | |
| GSE45670 | ARHGAP17 | 55114 | 218076_s_at | -0.3010 | 0.0150 | |
| GSE53622 | ARHGAP17 | 55114 | 95090 | -0.3294 | 0.0000 | |
| GSE53624 | ARHGAP17 | 55114 | 95090 | -0.3887 | 0.0000 | |
| GSE63941 | ARHGAP17 | 55114 | 218076_s_at | -2.0262 | 0.0001 | |
| GSE77861 | ARHGAP17 | 55114 | 218076_s_at | -0.2916 | 0.2697 | |
| GSE97050 | ARHGAP17 | 55114 | A_24_P401739 | -0.0310 | 0.9159 | |
| SRP007169 | ARHGAP17 | 55114 | RNAseq | -0.4736 | 0.3007 | |
| SRP008496 | ARHGAP17 | 55114 | RNAseq | -0.5541 | 0.0590 | |
| SRP064894 | ARHGAP17 | 55114 | RNAseq | -0.5914 | 0.0004 | |
| SRP133303 | ARHGAP17 | 55114 | RNAseq | -0.3707 | 0.0001 | |
| SRP159526 | ARHGAP17 | 55114 | RNAseq | -0.4694 | 0.0311 | |
| SRP193095 | ARHGAP17 | 55114 | RNAseq | -0.2681 | 0.0333 | |
| SRP219564 | ARHGAP17 | 55114 | RNAseq | -0.2272 | 0.3412 | |
| TCGA | ARHGAP17 | 55114 | RNAseq | -0.1636 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ARHGAP17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP17 | 55114 | 4 | 4 | 22 | |
| GSE20123 | ARHGAP17 | 55114 | 4 | 3 | 23 | |
| GSE43470 | ARHGAP17 | 55114 | 4 | 3 | 36 | |
| GSE46452 | ARHGAP17 | 55114 | 38 | 1 | 20 | |
| GSE47630 | ARHGAP17 | 55114 | 11 | 6 | 23 | |
| GSE54993 | ARHGAP17 | 55114 | 3 | 5 | 62 | |
| GSE54994 | ARHGAP17 | 55114 | 4 | 9 | 40 | |
| GSE60625 | ARHGAP17 | 55114 | 4 | 0 | 7 | |
| GSE74703 | ARHGAP17 | 55114 | 4 | 2 | 30 | |
| GSE74704 | ARHGAP17 | 55114 | 2 | 1 | 17 | |
| TCGA | ARHGAP17 | 55114 | 19 | 13 | 64 |
Total number of gains: 97; Total number of losses: 47; Total Number of normals: 344.
Somatic mutations of ARHGAP17:
Generating mutation plots.
Highly correlated genes for ARHGAP17:
Showing top 20/803 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP17 | ENG | 0.82303 | 3 | 0 | 3 |
| ARHGAP17 | COL15A1 | 0.753655 | 3 | 0 | 3 |
| ARHGAP17 | KCNJ8 | 0.752438 | 3 | 0 | 3 |
| ARHGAP17 | CSF1 | 0.74803 | 3 | 0 | 3 |
| ARHGAP17 | IL13RA2 | 0.746862 | 3 | 0 | 3 |
| ARHGAP17 | DSTYK | 0.746092 | 3 | 0 | 3 |
| ARHGAP17 | HNRNPL | 0.744899 | 3 | 0 | 3 |
| ARHGAP17 | SMAD3 | 0.741717 | 3 | 0 | 3 |
| ARHGAP17 | ANGPTL2 | 0.741481 | 3 | 0 | 3 |
| ARHGAP17 | ARMCX2 | 0.736659 | 3 | 0 | 3 |
| ARHGAP17 | RANBP10 | 0.736444 | 4 | 0 | 4 |
| ARHGAP17 | ZFAND5 | 0.734426 | 3 | 0 | 3 |
| ARHGAP17 | TMEM176B | 0.724553 | 3 | 0 | 3 |
| ARHGAP17 | MRPL39 | 0.723217 | 3 | 0 | 3 |
| ARHGAP17 | CNP | 0.720709 | 5 | 0 | 4 |
| ARHGAP17 | GLB1L | 0.720219 | 3 | 0 | 3 |
| ARHGAP17 | TBC1D16 | 0.711863 | 3 | 0 | 3 |
| ARHGAP17 | STAT5A | 0.710708 | 4 | 0 | 3 |
| ARHGAP17 | C3orf38 | 0.710062 | 3 | 0 | 3 |
| ARHGAP17 | WDFY1 | 0.709819 | 5 | 0 | 5 |
For details and further investigation, click here
