| Full name: ERGIC and golgi 3 | Alias Symbol: CGI-54|PRO0989|NY-BR-84|Erv46 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 51614 | HGNC ID: HGNC:15927 | Ensembl Gene: ENSG00000125991 | OMIM ID: 616971 |
| Drug and gene relationship at DGIdb | |||
Expression of ERGIC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERGIC3 | 51614 | 216032_s_at | 0.5834 | 0.1144 | |
| GSE20347 | ERGIC3 | 51614 | 216032_s_at | 0.0241 | 0.9128 | |
| GSE23400 | ERGIC3 | 51614 | 216032_s_at | 0.3025 | 0.0000 | |
| GSE26886 | ERGIC3 | 51614 | 216032_s_at | -0.5412 | 0.0881 | |
| GSE29001 | ERGIC3 | 51614 | 216032_s_at | 0.0651 | 0.8829 | |
| GSE38129 | ERGIC3 | 51614 | 216032_s_at | 0.2806 | 0.0796 | |
| GSE45670 | ERGIC3 | 51614 | 216032_s_at | 0.0799 | 0.6494 | |
| GSE53622 | ERGIC3 | 51614 | 27972 | 0.4192 | 0.0000 | |
| GSE53624 | ERGIC3 | 51614 | 27972 | 0.2253 | 0.0091 | |
| GSE63941 | ERGIC3 | 51614 | 216032_s_at | 1.4791 | 0.0150 | |
| GSE77861 | ERGIC3 | 51614 | 216032_s_at | -0.0827 | 0.6837 | |
| GSE97050 | ERGIC3 | 51614 | A_24_P216313 | 0.2932 | 0.2907 | |
| SRP007169 | ERGIC3 | 51614 | RNAseq | -0.9252 | 0.0022 | |
| SRP008496 | ERGIC3 | 51614 | RNAseq | -0.6150 | 0.0036 | |
| SRP064894 | ERGIC3 | 51614 | RNAseq | 0.4300 | 0.0931 | |
| SRP133303 | ERGIC3 | 51614 | RNAseq | 0.1413 | 0.2003 | |
| SRP159526 | ERGIC3 | 51614 | RNAseq | -0.0087 | 0.9485 | |
| SRP193095 | ERGIC3 | 51614 | RNAseq | -0.1158 | 0.3585 | |
| SRP219564 | ERGIC3 | 51614 | RNAseq | 0.5081 | 0.0535 | |
| TCGA | ERGIC3 | 51614 | RNAseq | -0.0061 | 0.8917 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ERGIC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERGIC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERGIC3 | 51614 | 15 | 1 | 14 | |
| GSE20123 | ERGIC3 | 51614 | 15 | 1 | 14 | |
| GSE43470 | ERGIC3 | 51614 | 13 | 0 | 30 | |
| GSE46452 | ERGIC3 | 51614 | 29 | 0 | 30 | |
| GSE47630 | ERGIC3 | 51614 | 25 | 0 | 15 | |
| GSE54993 | ERGIC3 | 51614 | 0 | 17 | 53 | |
| GSE54994 | ERGIC3 | 51614 | 24 | 0 | 29 | |
| GSE60625 | ERGIC3 | 51614 | 0 | 0 | 11 | |
| GSE74703 | ERGIC3 | 51614 | 11 | 0 | 25 | |
| GSE74704 | ERGIC3 | 51614 | 11 | 0 | 9 | |
| TCGA | ERGIC3 | 51614 | 49 | 3 | 44 |
Total number of gains: 192; Total number of losses: 22; Total Number of normals: 274.
Somatic mutations of ERGIC3:
Generating mutation plots.
Highly correlated genes for ERGIC3:
Showing top 20/766 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERGIC3 | SMCR8 | 0.783555 | 3 | 0 | 3 |
| ERGIC3 | ANKRD54 | 0.759438 | 3 | 0 | 3 |
| ERGIC3 | B9D2 | 0.754568 | 3 | 0 | 3 |
| ERGIC3 | PLIN2 | 0.746702 | 3 | 0 | 3 |
| ERGIC3 | TMED8 | 0.746565 | 3 | 0 | 3 |
| ERGIC3 | CDYL | 0.742042 | 3 | 0 | 3 |
| ERGIC3 | IGSF6 | 0.73978 | 4 | 0 | 3 |
| ERGIC3 | SDHAF2 | 0.737672 | 4 | 0 | 4 |
| ERGIC3 | HERPUD1 | 0.727859 | 3 | 0 | 3 |
| ERGIC3 | PRPF38A | 0.727328 | 3 | 0 | 3 |
| ERGIC3 | LEPROT | 0.724825 | 3 | 0 | 3 |
| ERGIC3 | NDUFS3 | 0.723446 | 4 | 0 | 3 |
| ERGIC3 | MAP3K1 | 0.717737 | 3 | 0 | 3 |
| ERGIC3 | CALML5 | 0.716686 | 3 | 0 | 3 |
| ERGIC3 | ZNF837 | 0.714592 | 3 | 0 | 3 |
| ERGIC3 | PSMB10 | 0.708871 | 3 | 0 | 3 |
| ERGIC3 | SNX12 | 0.706781 | 4 | 0 | 3 |
| ERGIC3 | TMEM54 | 0.704162 | 3 | 0 | 3 |
| ERGIC3 | PIGU | 0.70169 | 8 | 0 | 7 |
| ERGIC3 | KIAA1522 | 0.695368 | 4 | 0 | 4 |
For details and further investigation, click here
