| Full name: polyamine modulated factor 1 binding protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.2 | ||
| Entrez ID: 83449 | HGNC ID: HGNC:17728 | Ensembl Gene: ENSG00000118557 | OMIM ID: 618085 |
| Drug and gene relationship at DGIdb | |||
Expression of PMFBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PMFBP1 | 83449 | 221022_s_at | -0.1096 | 0.7308 | |
| GSE20347 | PMFBP1 | 83449 | 221022_s_at | -0.2331 | 0.0237 | |
| GSE23400 | PMFBP1 | 83449 | 221022_s_at | -0.1448 | 0.0002 | |
| GSE26886 | PMFBP1 | 83449 | 221022_s_at | -0.1315 | 0.3468 | |
| GSE29001 | PMFBP1 | 83449 | 221022_s_at | -0.0247 | 0.8737 | |
| GSE38129 | PMFBP1 | 83449 | 221022_s_at | -0.0881 | 0.4283 | |
| GSE45670 | PMFBP1 | 83449 | 221022_s_at | 0.2789 | 0.0760 | |
| GSE53622 | PMFBP1 | 83449 | 49956 | 0.7657 | 0.0000 | |
| GSE53624 | PMFBP1 | 83449 | 49956 | 1.0164 | 0.0000 | |
| GSE63941 | PMFBP1 | 83449 | 221022_s_at | 0.6320 | 0.0411 | |
| GSE77861 | PMFBP1 | 83449 | 221022_s_at | -0.3271 | 0.0293 | |
| SRP133303 | PMFBP1 | 83449 | RNAseq | -0.0702 | 0.8508 | |
| SRP159526 | PMFBP1 | 83449 | RNAseq | 1.1099 | 0.1307 | |
| SRP219564 | PMFBP1 | 83449 | RNAseq | 1.3695 | 0.0459 | |
| TCGA | PMFBP1 | 83449 | RNAseq | 1.2439 | 0.0002 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PMFBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PMFBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PMFBP1 | 83449 | 4 | 0 | 26 | |
| GSE20123 | PMFBP1 | 83449 | 4 | 0 | 26 | |
| GSE43470 | PMFBP1 | 83449 | 2 | 8 | 33 | |
| GSE46452 | PMFBP1 | 83449 | 38 | 2 | 19 | |
| GSE47630 | PMFBP1 | 83449 | 11 | 8 | 21 | |
| GSE54993 | PMFBP1 | 83449 | 2 | 4 | 64 | |
| GSE54994 | PMFBP1 | 83449 | 8 | 10 | 35 | |
| GSE60625 | PMFBP1 | 83449 | 4 | 0 | 7 | |
| GSE74703 | PMFBP1 | 83449 | 2 | 5 | 29 | |
| GSE74704 | PMFBP1 | 83449 | 2 | 0 | 18 | |
| TCGA | PMFBP1 | 83449 | 25 | 15 | 56 |
Total number of gains: 102; Total number of losses: 52; Total Number of normals: 334.
Somatic mutations of PMFBP1:
Generating mutation plots.
Highly correlated genes for PMFBP1:
Showing top 20/338 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PMFBP1 | UMOD | 0.69099 | 5 | 0 | 5 |
| PMFBP1 | GCG | 0.665538 | 3 | 0 | 3 |
| PMFBP1 | NR5A1 | 0.663118 | 5 | 0 | 5 |
| PMFBP1 | PRG3 | 0.654708 | 4 | 0 | 4 |
| PMFBP1 | NPY2R | 0.650264 | 3 | 0 | 3 |
| PMFBP1 | OR2H2 | 0.643067 | 4 | 0 | 4 |
| PMFBP1 | CCIN | 0.634421 | 5 | 0 | 5 |
| PMFBP1 | CRYBA4 | 0.633823 | 3 | 0 | 3 |
| PMFBP1 | MYO1A | 0.628014 | 5 | 0 | 3 |
| PMFBP1 | PRDM11 | 0.623505 | 7 | 0 | 6 |
| PMFBP1 | SLC28A2 | 0.618018 | 6 | 0 | 5 |
| PMFBP1 | SSTR4 | 0.617017 | 6 | 0 | 5 |
| PMFBP1 | IFNA21 | 0.616852 | 4 | 0 | 4 |
| PMFBP1 | HHLA1 | 0.616086 | 6 | 0 | 5 |
| PMFBP1 | RALYL | 0.611646 | 4 | 0 | 4 |
| PMFBP1 | SERPINC1 | 0.611304 | 4 | 0 | 3 |
| PMFBP1 | C5AR2 | 0.61031 | 5 | 0 | 5 |
| PMFBP1 | KIR2DS3 | 0.609969 | 4 | 0 | 4 |
| PMFBP1 | KRT76 | 0.605039 | 5 | 0 | 5 |
| PMFBP1 | KCNQ3 | 0.603412 | 6 | 0 | 4 |
For details and further investigation, click here
