POP4

 

Full name: POP4 homolog, ribonuclease P/MRP subunit Alias Symbol: RPP29
Type: protein-coding gene Cytoband: 19q12
Entrez ID: 10775 HGNC ID: HGNC:30081 Ensembl Gene: ENSG00000105171 OMIM ID: 606114
Screen Evidence:

 

Expression of POP4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 POP4 10775 202868_s_at -0.0043 0.9959
GSE20347 POP4 10775 202868_s_at -0.2510 0.1031
GSE23400 POP4 10775 202868_s_at 0.2404 0.0136
GSE26886 POP4 10775 202868_s_at -0.3621 0.0178
GSE29001 POP4 10775 202868_s_at -0.0221 0.9284
GSE38129 POP4 10775 202868_s_at 0.0009 0.9959
GSE45670 POP4 10775 202868_s_at 0.0753 0.5840
GSE53622 POP4 10775 73256 -0.1854 0.0162
GSE53624 POP4 10775 73256 0.0189 0.7984
GSE63941 POP4 10775 202868_s_at 0.1235 0.7943
GSE77861 POP4 10775 202868_s_at -0.2455 0.2398
GSE97050 POP4 10775 A_23_P90533 0.0478 0.8362
SRP007169 POP4 10775 RNAseq 0.8832 0.0560
SRP008496 POP4 10775 RNAseq 0.5156 0.1817
SRP064894 POP4 10775 RNAseq 0.2009 0.3588
SRP133303 POP4 10775 RNAseq -0.0123 0.9112
SRP159526 POP4 10775 RNAseq 0.3075 0.3105
SRP193095 POP4 10775 RNAseq -0.2522 0.0428
SRP219564 POP4 10775 RNAseq -0.2109 0.4543
TCGA POP4 10775 RNAseq 0.0714 0.2065

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by POP4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of POP4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 POP4 10775 6 7 17
GSE20123 POP4 10775 6 6 18
GSE43470 POP4 10775 6 6 31
GSE46452 POP4 10775 47 1 11
GSE47630 POP4 10775 8 6 26
GSE54993 POP4 10775 17 3 50
GSE54994 POP4 10775 7 11 35
GSE60625 POP4 10775 9 0 2
GSE74703 POP4 10775 6 4 26
GSE74704 POP4 10775 5 4 11
TCGA POP4 10775 17 14 65

Total number of gains: 134; Total number of losses: 62; Total Number of normals: 292.  


 

Somatic mutations of POP4:

 

Generating mutation plots.

 

Highly correlated genes for POP4:

 

Showing top 20/137 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
POP4GPANK10.754179303
POP4ZNF300.678319303
POP4SCYL20.674847303
POP4ZNF5640.662282403
POP4BCLAF10.644486404
POP4UQCRFS10.6430021209
POP4ZNF1750.630358303
POP4MBOAT10.623871403
POP4KCTD200.623228303
POP4POLR3B0.620815403
POP4CCDC1260.616406303
POP4SPCS10.613971705
POP4EIF4EBP20.608141303
POP4MMGT10.608093303
POP4RAF10.604173403
POP4PSEN10.603248504
POP4C1orf1220.601262403
POP4TM2D10.599904403
POP4MECOM0.598874303
POP4ECHDC10.598398303

For details and further investigation, click here