| Full name: ethylmalonyl-CoA decarboxylase 1 | Alias Symbol: dJ351K20.2 | ||
| Type: protein-coding gene | Cytoband: 6q22.33 | ||
| Entrez ID: 55862 | HGNC ID: HGNC:21489 | Ensembl Gene: ENSG00000093144 | OMIM ID: 612136 |
| Drug and gene relationship at DGIdb | |||
Expression of ECHDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ECHDC1 | 55862 | 223087_at | -0.2228 | 0.6433 | |
| GSE20347 | ECHDC1 | 55862 | 219974_x_at | 0.3517 | 0.0242 | |
| GSE23400 | ECHDC1 | 55862 | 219974_x_at | 0.3428 | 0.0000 | |
| GSE26886 | ECHDC1 | 55862 | 223087_at | -0.2307 | 0.2951 | |
| GSE29001 | ECHDC1 | 55862 | 219974_x_at | 0.5754 | 0.0272 | |
| GSE38129 | ECHDC1 | 55862 | 219974_x_at | 0.3897 | 0.0008 | |
| GSE45670 | ECHDC1 | 55862 | 223087_at | -0.2505 | 0.1869 | |
| GSE53622 | ECHDC1 | 55862 | 68411 | 0.0367 | 0.6093 | |
| GSE53624 | ECHDC1 | 55862 | 68411 | 0.2050 | 0.0026 | |
| GSE63941 | ECHDC1 | 55862 | 223087_at | -1.5409 | 0.3502 | |
| GSE77861 | ECHDC1 | 55862 | 223087_at | -0.5123 | 0.2009 | |
| GSE97050 | ECHDC1 | 55862 | A_23_P82206 | 0.0320 | 0.8960 | |
| SRP007169 | ECHDC1 | 55862 | RNAseq | -0.3000 | 0.4666 | |
| SRP008496 | ECHDC1 | 55862 | RNAseq | -0.3912 | 0.1160 | |
| SRP064894 | ECHDC1 | 55862 | RNAseq | 0.3313 | 0.0077 | |
| SRP133303 | ECHDC1 | 55862 | RNAseq | -0.0442 | 0.7936 | |
| SRP159526 | ECHDC1 | 55862 | RNAseq | -0.1021 | 0.6902 | |
| SRP193095 | ECHDC1 | 55862 | RNAseq | -0.3082 | 0.0128 | |
| SRP219564 | ECHDC1 | 55862 | RNAseq | -0.1424 | 0.6480 | |
| TCGA | ECHDC1 | 55862 | RNAseq | -0.1125 | 0.0201 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ECHDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ECHDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ECHDC1 | 55862 | 1 | 4 | 25 | |
| GSE20123 | ECHDC1 | 55862 | 2 | 3 | 25 | |
| GSE43470 | ECHDC1 | 55862 | 5 | 0 | 38 | |
| GSE46452 | ECHDC1 | 55862 | 2 | 11 | 46 | |
| GSE47630 | ECHDC1 | 55862 | 9 | 4 | 27 | |
| GSE54993 | ECHDC1 | 55862 | 3 | 3 | 64 | |
| GSE54994 | ECHDC1 | 55862 | 9 | 7 | 37 | |
| GSE60625 | ECHDC1 | 55862 | 0 | 1 | 10 | |
| GSE74703 | ECHDC1 | 55862 | 4 | 0 | 32 | |
| GSE74704 | ECHDC1 | 55862 | 0 | 1 | 19 | |
| TCGA | ECHDC1 | 55862 | 10 | 18 | 68 |
Total number of gains: 45; Total number of losses: 52; Total Number of normals: 391.
Somatic mutations of ECHDC1:
Generating mutation plots.
Highly correlated genes for ECHDC1:
Showing top 20/472 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ECHDC1 | CUL4B | 0.779432 | 3 | 0 | 3 |
| ECHDC1 | ZNF304 | 0.773062 | 4 | 0 | 4 |
| ECHDC1 | CD2AP | 0.771262 | 3 | 0 | 3 |
| ECHDC1 | ZNF543 | 0.760759 | 3 | 0 | 3 |
| ECHDC1 | MRPL1 | 0.725457 | 3 | 0 | 3 |
| ECHDC1 | ZNF277 | 0.716328 | 3 | 0 | 3 |
| ECHDC1 | LRRK2 | 0.715807 | 3 | 0 | 3 |
| ECHDC1 | IFNAR1 | 0.713083 | 3 | 0 | 3 |
| ECHDC1 | CASP4 | 0.710926 | 3 | 0 | 3 |
| ECHDC1 | GNL3 | 0.707676 | 4 | 0 | 4 |
| ECHDC1 | UFL1 | 0.707338 | 4 | 0 | 3 |
| ECHDC1 | NBPF1 | 0.699654 | 3 | 0 | 3 |
| ECHDC1 | ADH5 | 0.6985 | 3 | 0 | 3 |
| ECHDC1 | RINT1 | 0.692482 | 3 | 0 | 3 |
| ECHDC1 | LRRC47 | 0.689625 | 4 | 0 | 3 |
| ECHDC1 | SRSF8 | 0.685315 | 3 | 0 | 3 |
| ECHDC1 | SGMS1 | 0.684305 | 4 | 0 | 4 |
| ECHDC1 | MRPL42 | 0.684086 | 5 | 0 | 5 |
| ECHDC1 | RPA1 | 0.683451 | 5 | 0 | 5 |
| ECHDC1 | SPIN3 | 0.683147 | 3 | 0 | 3 |
For details and further investigation, click here
