| Full name: TM2 domain containing 1 | Alias Symbol: BBP | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 83941 | HGNC ID: HGNC:24142 | Ensembl Gene: ENSG00000162604 | OMIM ID: 610080 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TM2D1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TM2D1 | 83941 | 213883_s_at | 0.3118 | 0.3893 | |
| GSE20347 | TM2D1 | 83941 | 213883_s_at | 0.3086 | 0.0450 | |
| GSE23400 | TM2D1 | 83941 | 211703_s_at | 0.2223 | 0.0003 | |
| GSE26886 | TM2D1 | 83941 | 213883_s_at | 0.3857 | 0.0072 | |
| GSE29001 | TM2D1 | 83941 | 213883_s_at | 0.2757 | 0.2474 | |
| GSE38129 | TM2D1 | 83941 | 213883_s_at | 0.2531 | 0.0261 | |
| GSE45670 | TM2D1 | 83941 | 213883_s_at | -0.0810 | 0.5999 | |
| GSE53622 | TM2D1 | 83941 | 5727 | 0.1218 | 0.0129 | |
| GSE53624 | TM2D1 | 83941 | 5727 | 0.0974 | 0.1135 | |
| GSE63941 | TM2D1 | 83941 | 213883_s_at | -0.7330 | 0.0761 | |
| GSE77861 | TM2D1 | 83941 | 213883_s_at | 0.0400 | 0.9118 | |
| GSE97050 | TM2D1 | 83941 | A_33_P3279940 | 0.0632 | 0.7519 | |
| SRP007169 | TM2D1 | 83941 | RNAseq | -0.3681 | 0.3363 | |
| SRP008496 | TM2D1 | 83941 | RNAseq | -0.2128 | 0.4335 | |
| SRP064894 | TM2D1 | 83941 | RNAseq | 0.0336 | 0.8413 | |
| SRP133303 | TM2D1 | 83941 | RNAseq | 0.5204 | 0.0364 | |
| SRP159526 | TM2D1 | 83941 | RNAseq | -0.2890 | 0.1867 | |
| SRP193095 | TM2D1 | 83941 | RNAseq | -0.0480 | 0.6435 | |
| SRP219564 | TM2D1 | 83941 | RNAseq | -0.0758 | 0.7609 | |
| TCGA | TM2D1 | 83941 | RNAseq | 0.0387 | 0.5968 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TM2D1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TM2D1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TM2D1 | 83941 | 2 | 5 | 23 | |
| GSE20123 | TM2D1 | 83941 | 2 | 5 | 23 | |
| GSE43470 | TM2D1 | 83941 | 5 | 2 | 36 | |
| GSE46452 | TM2D1 | 83941 | 2 | 1 | 56 | |
| GSE47630 | TM2D1 | 83941 | 8 | 5 | 27 | |
| GSE54993 | TM2D1 | 83941 | 0 | 0 | 70 | |
| GSE54994 | TM2D1 | 83941 | 6 | 4 | 43 | |
| GSE60625 | TM2D1 | 83941 | 0 | 0 | 11 | |
| GSE74703 | TM2D1 | 83941 | 4 | 2 | 30 | |
| GSE74704 | TM2D1 | 83941 | 1 | 2 | 17 | |
| TCGA | TM2D1 | 83941 | 11 | 20 | 65 |
Total number of gains: 41; Total number of losses: 46; Total Number of normals: 401.
Somatic mutations of TM2D1:
Generating mutation plots.
Highly correlated genes for TM2D1:
Showing top 20/516 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TM2D1 | HPS3 | 0.756744 | 3 | 0 | 3 |
| TM2D1 | DDX54 | 0.718277 | 3 | 0 | 3 |
| TM2D1 | ELOF1 | 0.7106 | 3 | 0 | 3 |
| TM2D1 | PEMT | 0.699241 | 3 | 0 | 3 |
| TM2D1 | ALG1 | 0.694432 | 3 | 0 | 3 |
| TM2D1 | ITGB8 | 0.688132 | 3 | 0 | 3 |
| TM2D1 | TMED2 | 0.682935 | 3 | 0 | 3 |
| TM2D1 | SNX30 | 0.678313 | 3 | 0 | 3 |
| TM2D1 | CEP89 | 0.67766 | 3 | 0 | 3 |
| TM2D1 | UBE2J2 | 0.664634 | 4 | 0 | 3 |
| TM2D1 | CDC37 | 0.66442 | 3 | 0 | 3 |
| TM2D1 | FBXW8 | 0.662966 | 3 | 0 | 3 |
| TM2D1 | PHF20 | 0.660793 | 3 | 0 | 3 |
| TM2D1 | PIGL | 0.659374 | 3 | 0 | 3 |
| TM2D1 | CSTF1 | 0.658273 | 5 | 0 | 5 |
| TM2D1 | AGPAT5 | 0.655918 | 4 | 0 | 3 |
| TM2D1 | CHUK | 0.654999 | 4 | 0 | 4 |
| TM2D1 | EME1 | 0.654724 | 3 | 0 | 3 |
| TM2D1 | CHERP | 0.6539 | 4 | 0 | 3 |
| TM2D1 | LRRC58 | 0.653015 | 3 | 0 | 3 |
For details and further investigation, click here
