| Full name: porcupine O-acyltransferase | Alias Symbol: MG61|PORC|PPN|por | ||
| Type: protein-coding gene | Cytoband: Xp11.23 | ||
| Entrez ID: 64840 | HGNC ID: HGNC:17652 | Ensembl Gene: ENSG00000102312 | OMIM ID: 300651 |
| Drug and gene relationship at DGIdb | |||
PORCN involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04310 | Wnt signaling pathway |
Expression of PORCN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PORCN | 64840 | 219483_s_at | -0.1931 | 0.7293 | |
| GSE20347 | PORCN | 64840 | 219483_s_at | -0.5450 | 0.0424 | |
| GSE23400 | PORCN | 64840 | 219483_s_at | -0.6055 | 0.0000 | |
| GSE26886 | PORCN | 64840 | 219483_s_at | -1.0514 | 0.0004 | |
| GSE29001 | PORCN | 64840 | 219483_s_at | -1.0854 | 0.0131 | |
| GSE38129 | PORCN | 64840 | 219483_s_at | -0.4746 | 0.0182 | |
| GSE45670 | PORCN | 64840 | 219483_s_at | -0.0060 | 0.9897 | |
| GSE53622 | PORCN | 64840 | 25539 | -0.4187 | 0.0000 | |
| GSE53624 | PORCN | 64840 | 25539 | -0.6809 | 0.0000 | |
| GSE63941 | PORCN | 64840 | 219483_s_at | -0.0192 | 0.9815 | |
| GSE77861 | PORCN | 64840 | 219483_s_at | -0.2976 | 0.1869 | |
| GSE97050 | PORCN | 64840 | A_33_P3237784 | -0.2758 | 0.3744 | |
| SRP007169 | PORCN | 64840 | RNAseq | -4.8947 | 0.0000 | |
| SRP008496 | PORCN | 64840 | RNAseq | -3.9155 | 0.0000 | |
| SRP064894 | PORCN | 64840 | RNAseq | -1.7091 | 0.0000 | |
| SRP133303 | PORCN | 64840 | RNAseq | -0.7575 | 0.0124 | |
| SRP159526 | PORCN | 64840 | RNAseq | -0.8922 | 0.0042 | |
| SRP193095 | PORCN | 64840 | RNAseq | -1.3525 | 0.0000 | |
| SRP219564 | PORCN | 64840 | RNAseq | -0.3754 | 0.4247 | |
| TCGA | PORCN | 64840 | RNAseq | 0.0702 | 0.5035 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by PORCN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PORCN:
No record found for this gene.
Somatic mutations of PORCN:
Generating mutation plots.
Highly correlated genes for PORCN:
Showing top 20/730 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PORCN | CEPT1 | 0.72927 | 3 | 0 | 3 |
| PORCN | CCNYL1 | 0.725629 | 4 | 0 | 4 |
| PORCN | RELA | 0.710382 | 3 | 0 | 3 |
| PORCN | SRP14 | 0.705065 | 3 | 0 | 3 |
| PORCN | CLDN11 | 0.694985 | 3 | 0 | 3 |
| PORCN | APH1A | 0.685947 | 3 | 0 | 3 |
| PORCN | NAPRT | 0.680398 | 3 | 0 | 3 |
| PORCN | ACTB | 0.680006 | 3 | 0 | 3 |
| PORCN | LACTBL1 | 0.679989 | 3 | 0 | 3 |
| PORCN | CAMK2G | 0.67434 | 3 | 0 | 3 |
| PORCN | C1orf56 | 0.667846 | 3 | 0 | 3 |
| PORCN | GSTT2 | 0.660736 | 4 | 0 | 3 |
| PORCN | ZFP36L1 | 0.65915 | 3 | 0 | 3 |
| PORCN | VAX2 | 0.657272 | 3 | 0 | 3 |
| PORCN | FUT11 | 0.656452 | 3 | 0 | 3 |
| PORCN | TOM1 | 0.656241 | 11 | 0 | 10 |
| PORCN | TAS2R38 | 0.653929 | 3 | 0 | 3 |
| PORCN | VAT1 | 0.65346 | 11 | 0 | 10 |
| PORCN | THAP2 | 0.652443 | 3 | 0 | 3 |
| PORCN | SH3GL1 | 0.650103 | 11 | 0 | 11 |
For details and further investigation, click here
