| Full name: protein phosphatase 1 regulatory subunit 16B | Alias Symbol: KIAA0823|TIMAP|ANKRD4 | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 26051 | HGNC ID: HGNC:15850 | Ensembl Gene: ENSG00000101445 | OMIM ID: 613275 |
| Drug and gene relationship at DGIdb | |||
Expression of PPP1R16B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R16B | 26051 | 212750_at | 0.3353 | 0.7758 | |
| GSE20347 | PPP1R16B | 26051 | 212750_at | -0.2282 | 0.0504 | |
| GSE23400 | PPP1R16B | 26051 | 212750_at | -0.1479 | 0.0006 | |
| GSE26886 | PPP1R16B | 26051 | 212750_at | -0.5264 | 0.0057 | |
| GSE29001 | PPP1R16B | 26051 | 212750_at | -0.3848 | 0.0243 | |
| GSE38129 | PPP1R16B | 26051 | 212750_at | -0.4239 | 0.0214 | |
| GSE45670 | PPP1R16B | 26051 | 212750_at | -0.5017 | 0.1156 | |
| GSE63941 | PPP1R16B | 26051 | 233813_at | 0.1792 | 0.1454 | |
| GSE77861 | PPP1R16B | 26051 | 212750_at | 0.0244 | 0.8425 | |
| GSE97050 | PPP1R16B | 26051 | A_23_P352535 | 0.2145 | 0.4929 | |
| SRP007169 | PPP1R16B | 26051 | RNAseq | -1.7002 | 0.0013 | |
| SRP064894 | PPP1R16B | 26051 | RNAseq | -0.1238 | 0.7140 | |
| SRP133303 | PPP1R16B | 26051 | RNAseq | -1.0973 | 0.0000 | |
| SRP159526 | PPP1R16B | 26051 | RNAseq | -0.7220 | 0.1436 | |
| SRP193095 | PPP1R16B | 26051 | RNAseq | -0.2406 | 0.4121 | |
| SRP219564 | PPP1R16B | 26051 | RNAseq | -0.1513 | 0.7209 | |
| TCGA | PPP1R16B | 26051 | RNAseq | -0.7364 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PPP1R16B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PPP1R16B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R16B | 26051 | 14 | 2 | 14 | |
| GSE20123 | PPP1R16B | 26051 | 14 | 2 | 14 | |
| GSE43470 | PPP1R16B | 26051 | 13 | 0 | 30 | |
| GSE46452 | PPP1R16B | 26051 | 29 | 0 | 30 | |
| GSE47630 | PPP1R16B | 26051 | 24 | 0 | 16 | |
| GSE54993 | PPP1R16B | 26051 | 0 | 17 | 53 | |
| GSE54994 | PPP1R16B | 26051 | 24 | 0 | 29 | |
| GSE60625 | PPP1R16B | 26051 | 0 | 0 | 11 | |
| GSE74703 | PPP1R16B | 26051 | 10 | 0 | 26 | |
| GSE74704 | PPP1R16B | 26051 | 10 | 1 | 9 | |
| TCGA | PPP1R16B | 26051 | 47 | 4 | 45 |
Total number of gains: 185; Total number of losses: 26; Total Number of normals: 277.
Somatic mutations of PPP1R16B:
Generating mutation plots.
Highly correlated genes for PPP1R16B:
Showing top 20/356 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R16B | SERPINA1 | 0.803817 | 3 | 0 | 3 |
| PPP1R16B | C1orf162 | 0.763024 | 4 | 0 | 4 |
| PPP1R16B | GIMAP7 | 0.75996 | 5 | 0 | 5 |
| PPP1R16B | IRF8 | 0.756182 | 8 | 0 | 8 |
| PPP1R16B | TAGAP | 0.75126 | 3 | 0 | 3 |
| PPP1R16B | SPOCK2 | 0.749443 | 5 | 0 | 5 |
| PPP1R16B | CD48 | 0.749412 | 8 | 0 | 8 |
| PPP1R16B | PREX1 | 0.748261 | 4 | 0 | 3 |
| PPP1R16B | AKNA | 0.747194 | 3 | 0 | 3 |
| PPP1R16B | GLCCI1 | 0.746504 | 3 | 0 | 3 |
| PPP1R16B | TNFSF8 | 0.743097 | 3 | 0 | 3 |
| PPP1R16B | MS4A4A | 0.740006 | 3 | 0 | 3 |
| PPP1R16B | PIK3CG | 0.73673 | 4 | 0 | 4 |
| PPP1R16B | RGS18 | 0.73664 | 4 | 0 | 4 |
| PPP1R16B | P2RY8 | 0.715959 | 5 | 0 | 5 |
| PPP1R16B | SNX20 | 0.701313 | 5 | 0 | 4 |
| PPP1R16B | ANKRD44 | 0.701125 | 4 | 0 | 3 |
| PPP1R16B | TLR1 | 0.698731 | 4 | 0 | 4 |
| PPP1R16B | CD37 | 0.698584 | 7 | 0 | 7 |
| PPP1R16B | MPEG1 | 0.696616 | 5 | 0 | 4 |
For details and further investigation, click here
