| Full name: transmembrane protein 41A | Alias Symbol: MGC15397 | ||
| Type: protein-coding gene | Cytoband: 3q27.2 | ||
| Entrez ID: 90407 | HGNC ID: HGNC:30544 | Ensembl Gene: ENSG00000163900 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM41A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM41A | 90407 | 225991_at | 0.4896 | 0.4419 | |
| GSE26886 | TMEM41A | 90407 | 235037_at | -0.5108 | 0.0074 | |
| GSE45670 | TMEM41A | 90407 | 235037_at | 0.4615 | 0.0219 | |
| GSE53622 | TMEM41A | 90407 | 11161 | 0.3750 | 0.0005 | |
| GSE53624 | TMEM41A | 90407 | 11161 | 0.2176 | 0.0226 | |
| GSE63941 | TMEM41A | 90407 | 235037_at | 1.5836 | 0.0020 | |
| GSE77861 | TMEM41A | 90407 | 235037_at | 0.1265 | 0.5163 | |
| GSE97050 | TMEM41A | 90407 | A_23_P80832 | 0.5217 | 0.3118 | |
| SRP007169 | TMEM41A | 90407 | RNAseq | -0.4722 | 0.1918 | |
| SRP008496 | TMEM41A | 90407 | RNAseq | -0.0336 | 0.8906 | |
| SRP064894 | TMEM41A | 90407 | RNAseq | 0.2070 | 0.2955 | |
| SRP133303 | TMEM41A | 90407 | RNAseq | 0.4100 | 0.0528 | |
| SRP159526 | TMEM41A | 90407 | RNAseq | 0.6372 | 0.1081 | |
| SRP193095 | TMEM41A | 90407 | RNAseq | 0.1290 | 0.3563 | |
| SRP219564 | TMEM41A | 90407 | RNAseq | -0.2135 | 0.6707 | |
| TCGA | TMEM41A | 90407 | RNAseq | 0.3040 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMEM41A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM41A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM41A | 90407 | 25 | 0 | 5 | |
| GSE20123 | TMEM41A | 90407 | 25 | 0 | 5 | |
| GSE43470 | TMEM41A | 90407 | 23 | 0 | 20 | |
| GSE46452 | TMEM41A | 90407 | 19 | 1 | 39 | |
| GSE47630 | TMEM41A | 90407 | 27 | 2 | 11 | |
| GSE54993 | TMEM41A | 90407 | 1 | 19 | 50 | |
| GSE54994 | TMEM41A | 90407 | 40 | 0 | 13 | |
| GSE60625 | TMEM41A | 90407 | 0 | 6 | 5 | |
| GSE74703 | TMEM41A | 90407 | 20 | 0 | 16 | |
| GSE74704 | TMEM41A | 90407 | 17 | 0 | 3 | |
| TCGA | TMEM41A | 90407 | 77 | 0 | 19 |
Total number of gains: 274; Total number of losses: 28; Total Number of normals: 186.
Somatic mutations of TMEM41A:
Generating mutation plots.
Highly correlated genes for TMEM41A:
Showing top 20/507 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM41A | LTBR | 0.862357 | 3 | 0 | 3 |
| TMEM41A | MRPL11 | 0.800305 | 3 | 0 | 3 |
| TMEM41A | CDK2AP2 | 0.765685 | 3 | 0 | 3 |
| TMEM41A | SF3B2 | 0.752076 | 3 | 0 | 3 |
| TMEM41A | TMPO | 0.750963 | 3 | 0 | 3 |
| TMEM41A | DRAP1 | 0.749682 | 3 | 0 | 3 |
| TMEM41A | UBA1 | 0.749544 | 3 | 0 | 3 |
| TMEM41A | RNFT2 | 0.74581 | 3 | 0 | 3 |
| TMEM41A | PLEKHM2 | 0.745162 | 3 | 0 | 3 |
| TMEM41A | RAB7A | 0.736331 | 5 | 0 | 5 |
| TMEM41A | PSMG3 | 0.735003 | 4 | 0 | 4 |
| TMEM41A | TRMT2B | 0.723851 | 3 | 0 | 3 |
| TMEM41A | USP10 | 0.719011 | 3 | 0 | 3 |
| TMEM41A | ZBTB33 | 0.718829 | 3 | 0 | 3 |
| TMEM41A | INO80E | 0.718186 | 3 | 0 | 3 |
| TMEM41A | AP2M1 | 0.716791 | 7 | 0 | 6 |
| TMEM41A | ALG3 | 0.706283 | 7 | 0 | 5 |
| TMEM41A | PPP2R2D | 0.706231 | 3 | 0 | 3 |
| TMEM41A | PRELID1 | 0.704225 | 3 | 0 | 3 |
| TMEM41A | FRMD8 | 0.703407 | 3 | 0 | 3 |
For details and further investigation, click here
