STC2

 

Full name: stanniocalcin 2 Alias Symbol: STC-2
Type: protein-coding gene Cytoband: 5q35.2
Entrez ID: 8614 HGNC ID: HGNC:11374 Ensembl Gene: ENSG00000113739 OMIM ID: 603665
Drug and gene relationship at DGIdb

 

Expression of STC2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 STC2 8614 203438_at 1.5802 0.0443
GSE20347 STC2 8614 203438_at 1.1130 0.0000
GSE23400 STC2 8614 203438_at 0.2476 0.0004
GSE26886 STC2 8614 203439_s_at 1.2378 0.0000
GSE29001 STC2 8614 203439_s_at 2.1074 0.0012
GSE38129 STC2 8614 203438_at 1.1561 0.0000
GSE45670 STC2 8614 203439_s_at 1.1322 0.0026
GSE53622 STC2 8614 28676 2.3268 0.0000
GSE53624 STC2 8614 28676 2.9251 0.0000
GSE63941 STC2 8614 203438_at -2.5769 0.0671
GSE77861 STC2 8614 203439_s_at 0.3930 0.0912
GSE97050 STC2 8614 A_23_P416395 0.6486 0.1265
SRP007169 STC2 8614 RNAseq 5.9503 0.0000
SRP008496 STC2 8614 RNAseq 5.7645 0.0000
SRP064894 STC2 8614 RNAseq 3.0430 0.0000
SRP133303 STC2 8614 RNAseq 3.4701 0.0000
SRP159526 STC2 8614 RNAseq 2.9506 0.0000
SRP219564 STC2 8614 RNAseq 1.3666 0.0690
TCGA STC2 8614 RNAseq 1.0747 0.0000

Upregulated datasets: 14; Downregulated datasets: 0.  

 

Survival by STC2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of STC2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 STC2 8614 2 13 15
GSE20123 STC2 8614 2 13 15
GSE43470 STC2 8614 2 10 31
GSE46452 STC2 8614 0 27 32
GSE47630 STC2 8614 0 20 20
GSE54993 STC2 8614 9 2 59
GSE54994 STC2 8614 2 17 34
GSE60625 STC2 8614 1 0 10
GSE74703 STC2 8614 2 7 27
GSE74704 STC2 8614 1 6 13
TCGA STC2 8614 8 34 54

Total number of gains: 29; Total number of losses: 149; Total Number of normals: 310.  

 

Somatic mutations of STC2:

 

Generating mutation plots.

 

Highly correlated genes for STC2:

 

Showing top 20/1819 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
STC2NTMT10.806633606
STC2PYCR20.802388303
STC2BOLA30.787212606
STC2C16orf740.784878707
STC2FAM89A0.772144303
STC2KNSTRN0.769164505
STC2ZNF1140.756368404
STC2SLC35B20.755216303
STC2C6orf1410.755195303
STC2GNG100.750841303
STC2MAP4K40.750786404
STC2USB10.749861908
STC2FCGR3A0.746416303
STC2TP53I130.744373606
STC2SCNM10.744262303
STC2NGF0.744016404
STC2CYTH30.738077404
STC2LPCAT10.737921009
STC2PHRF10.736545303
STC2ABCB60.73643303

For details and further investigation, click here