| Full name: phosphofurin acidic cluster sorting protein 2 | Alias Symbol: KIAA0602 | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 23241 | HGNC ID: HGNC:23794 | Ensembl Gene: ENSG00000179364 | OMIM ID: 610423 |
| Drug and gene relationship at DGIdb | |||
Expression of PACS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PACS2 | 23241 | 1555823_at | -0.1507 | 0.6858 | |
| GSE20347 | PACS2 | 23241 | 34406_at | 0.2935 | 0.0139 | |
| GSE23400 | PACS2 | 23241 | 212778_at | 0.2177 | 0.0003 | |
| GSE26886 | PACS2 | 23241 | 1555823_at | -0.2482 | 0.0511 | |
| GSE29001 | PACS2 | 23241 | 34406_at | 0.0552 | 0.7793 | |
| GSE38129 | PACS2 | 23241 | 34406_at | 0.1937 | 0.0830 | |
| GSE45670 | PACS2 | 23241 | 1555823_at | -0.0339 | 0.7527 | |
| GSE53622 | PACS2 | 23241 | 41033 | -0.4896 | 0.0000 | |
| GSE53624 | PACS2 | 23241 | 41033 | -0.2081 | 0.0294 | |
| GSE63941 | PACS2 | 23241 | 1555823_at | 0.2455 | 0.1352 | |
| GSE77861 | PACS2 | 23241 | 1555823_at | -0.0583 | 0.5696 | |
| GSE97050 | PACS2 | 23241 | A_24_P393372 | -0.2523 | 0.4797 | |
| SRP007169 | PACS2 | 23241 | RNAseq | 0.3178 | 0.5035 | |
| SRP008496 | PACS2 | 23241 | RNAseq | 0.2567 | 0.4242 | |
| SRP064894 | PACS2 | 23241 | RNAseq | 0.6103 | 0.0024 | |
| SRP133303 | PACS2 | 23241 | RNAseq | 0.1594 | 0.3517 | |
| SRP159526 | PACS2 | 23241 | RNAseq | 0.6196 | 0.1723 | |
| SRP193095 | PACS2 | 23241 | RNAseq | 0.6020 | 0.0000 | |
| SRP219564 | PACS2 | 23241 | RNAseq | 0.2172 | 0.5463 | |
| TCGA | PACS2 | 23241 | RNAseq | -0.1228 | 0.0082 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PACS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PACS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PACS2 | 23241 | 11 | 3 | 16 | |
| GSE20123 | PACS2 | 23241 | 10 | 2 | 18 | |
| GSE43470 | PACS2 | 23241 | 5 | 3 | 35 | |
| GSE46452 | PACS2 | 23241 | 18 | 4 | 37 | |
| GSE47630 | PACS2 | 23241 | 11 | 10 | 19 | |
| GSE54993 | PACS2 | 23241 | 4 | 11 | 55 | |
| GSE54994 | PACS2 | 23241 | 21 | 4 | 28 | |
| GSE60625 | PACS2 | 23241 | 0 | 2 | 9 | |
| GSE74703 | PACS2 | 23241 | 4 | 3 | 29 | |
| GSE74704 | PACS2 | 23241 | 5 | 2 | 13 | |
| TCGA | PACS2 | 23241 | 31 | 18 | 47 |
Total number of gains: 120; Total number of losses: 62; Total Number of normals: 306.
Somatic mutations of PACS2:
Generating mutation plots.
Highly correlated genes for PACS2:
Showing top 20/165 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PACS2 | LIX1L | 0.779795 | 3 | 0 | 3 |
| PACS2 | GSX1 | 0.7679 | 3 | 0 | 3 |
| PACS2 | KIF9-AS1 | 0.70028 | 3 | 0 | 3 |
| PACS2 | CXCR1 | 0.694227 | 3 | 0 | 3 |
| PACS2 | C2orf16 | 0.681377 | 3 | 0 | 3 |
| PACS2 | PRB1 | 0.681328 | 3 | 0 | 3 |
| PACS2 | RAB4B | 0.67739 | 4 | 0 | 4 |
| PACS2 | CYGB | 0.676919 | 3 | 0 | 3 |
| PACS2 | GPR31 | 0.676378 | 3 | 0 | 3 |
| PACS2 | KRT81 | 0.669851 | 3 | 0 | 3 |
| PACS2 | TSHZ3 | 0.668938 | 3 | 0 | 3 |
| PACS2 | ITPR1 | 0.666792 | 4 | 0 | 3 |
| PACS2 | GPR3 | 0.662407 | 4 | 0 | 3 |
| PACS2 | CLSTN2 | 0.659887 | 3 | 0 | 3 |
| PACS2 | CRTC3 | 0.659648 | 5 | 0 | 4 |
| PACS2 | SEC31B | 0.656602 | 3 | 0 | 3 |
| PACS2 | KIF25-AS1 | 0.649711 | 3 | 0 | 3 |
| PACS2 | RBL2 | 0.646179 | 3 | 0 | 3 |
| PACS2 | ZNF747 | 0.642599 | 4 | 0 | 3 |
| PACS2 | STAT5B | 0.63789 | 4 | 0 | 3 |
For details and further investigation, click here
