| Full name: sorting nexin 11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 29916 | HGNC ID: HGNC:14975 | Ensembl Gene: ENSG00000002919 | OMIM ID: 614906 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX11 | 29916 | 53912_at | -0.1505 | 0.5513 | |
| GSE20347 | SNX11 | 29916 | 53912_at | -0.2193 | 0.0017 | |
| GSE23400 | SNX11 | 29916 | 220140_s_at | -0.1195 | 0.0115 | |
| GSE26886 | SNX11 | 29916 | 53912_at | -0.7196 | 0.0000 | |
| GSE29001 | SNX11 | 29916 | 53912_at | -0.3504 | 0.0190 | |
| GSE38129 | SNX11 | 29916 | 53912_at | -0.1647 | 0.0078 | |
| GSE45670 | SNX11 | 29916 | 53912_at | 0.0704 | 0.6172 | |
| GSE53622 | SNX11 | 29916 | 116889 | -0.2550 | 0.0001 | |
| GSE53624 | SNX11 | 29916 | 116889 | -0.3091 | 0.0000 | |
| GSE63941 | SNX11 | 29916 | 53912_at | -0.2185 | 0.4217 | |
| GSE77861 | SNX11 | 29916 | 53912_at | -0.1601 | 0.0830 | |
| GSE97050 | SNX11 | 29916 | A_23_P89343 | 0.0461 | 0.8869 | |
| SRP007169 | SNX11 | 29916 | RNAseq | -1.0746 | 0.0015 | |
| SRP008496 | SNX11 | 29916 | RNAseq | -1.0923 | 0.0000 | |
| SRP064894 | SNX11 | 29916 | RNAseq | -0.2737 | 0.1404 | |
| SRP133303 | SNX11 | 29916 | RNAseq | -0.4059 | 0.0014 | |
| SRP159526 | SNX11 | 29916 | RNAseq | -0.6330 | 0.0116 | |
| SRP193095 | SNX11 | 29916 | RNAseq | -0.5255 | 0.0000 | |
| SRP219564 | SNX11 | 29916 | RNAseq | -0.8240 | 0.0193 | |
| TCGA | SNX11 | 29916 | RNAseq | -0.0587 | 0.2782 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SNX11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX11 | 29916 | 5 | 2 | 23 | |
| GSE20123 | SNX11 | 29916 | 5 | 2 | 23 | |
| GSE43470 | SNX11 | 29916 | 2 | 2 | 39 | |
| GSE46452 | SNX11 | 29916 | 32 | 0 | 27 | |
| GSE47630 | SNX11 | 29916 | 9 | 0 | 31 | |
| GSE54993 | SNX11 | 29916 | 2 | 4 | 64 | |
| GSE54994 | SNX11 | 29916 | 11 | 5 | 37 | |
| GSE60625 | SNX11 | 29916 | 4 | 0 | 7 | |
| GSE74703 | SNX11 | 29916 | 2 | 1 | 33 | |
| GSE74704 | SNX11 | 29916 | 4 | 1 | 15 | |
| TCGA | SNX11 | 29916 | 27 | 6 | 63 |
Total number of gains: 103; Total number of losses: 23; Total Number of normals: 362.
Somatic mutations of SNX11:
Generating mutation plots.
Highly correlated genes for SNX11:
Showing top 20/319 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX11 | FAM71C | 0.739791 | 3 | 0 | 3 |
| SNX11 | PDE6G | 0.715642 | 3 | 0 | 3 |
| SNX11 | PRDM12 | 0.703438 | 3 | 0 | 3 |
| SNX11 | RAX | 0.701439 | 3 | 0 | 3 |
| SNX11 | NDOR1 | 0.699172 | 4 | 0 | 4 |
| SNX11 | SNORA68 | 0.682047 | 3 | 0 | 3 |
| SNX11 | IFNA10 | 0.679835 | 3 | 0 | 3 |
| SNX11 | TAAR5 | 0.657527 | 5 | 0 | 3 |
| SNX11 | TAS2R3 | 0.644076 | 3 | 0 | 3 |
| SNX11 | SPCS1 | 0.641137 | 5 | 0 | 3 |
| SNX11 | LPO | 0.638216 | 3 | 0 | 3 |
| SNX11 | OR2H2 | 0.638165 | 3 | 0 | 3 |
| SNX11 | PTH1R | 0.631103 | 4 | 0 | 4 |
| SNX11 | KLB | 0.628416 | 6 | 0 | 5 |
| SNX11 | SLC22A14 | 0.626792 | 4 | 0 | 3 |
| SNX11 | SPAG17 | 0.625594 | 4 | 0 | 3 |
| SNX11 | TUNAR | 0.624496 | 3 | 0 | 3 |
| SNX11 | CCL1 | 0.616549 | 3 | 0 | 3 |
| SNX11 | CD1C | 0.615654 | 5 | 0 | 5 |
| SNX11 | TRIM25 | 0.614237 | 5 | 0 | 4 |
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