SELP

 

Full name: selectin P Alias Symbol: CD62|PSEL|PADGEM|GMP140|CD62P
Type: protein-coding gene Cytoband: 1q24.2
Entrez ID: 6403 HGNC ID: HGNC:10721 Ensembl Gene: ENSG00000174175 OMIM ID: 173610
Drug and gene relationship at DGIdb

 

Expression of SELP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SELP 6403 206049_at -0.6311 0.5628
GSE20347 SELP 6403 206049_at -0.3006 0.0038
GSE23400 SELP 6403 206049_at -0.2557 0.0000
GSE26886 SELP 6403 206049_at -0.7670 0.0035
GSE29001 SELP 6403 206049_at -0.3977 0.0220
GSE38129 SELP 6403 206049_at -0.4583 0.0084
GSE45670 SELP 6403 206049_at -0.6498 0.0569
GSE53622 SELP 6403 58735 -1.3075 0.0000
GSE53624 SELP 6403 58735 -0.9884 0.0000
GSE63941 SELP 6403 206049_at -0.1034 0.5320
GSE77861 SELP 6403 206049_at -0.0393 0.9198
GSE97050 SELP 6403 A_33_P3339100 0.4948 0.3058
SRP064894 SELP 6403 RNAseq 0.0837 0.8633
SRP133303 SELP 6403 RNAseq -1.0760 0.0045
SRP159526 SELP 6403 RNAseq 0.1337 0.8877
SRP219564 SELP 6403 RNAseq 0.0302 0.9752
TCGA SELP 6403 RNAseq -0.8780 0.0259

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by SELP expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SELP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SELP 6403 11 1 18
GSE20123 SELP 6403 11 1 18
GSE43470 SELP 6403 7 2 34
GSE46452 SELP 6403 3 1 55
GSE47630 SELP 6403 14 0 26
GSE54993 SELP 6403 0 6 64
GSE54994 SELP 6403 16 0 37
GSE60625 SELP 6403 0 0 11
GSE74703 SELP 6403 7 2 27
GSE74704 SELP 6403 5 0 15
TCGA SELP 6403 43 3 50

Total number of gains: 117; Total number of losses: 16; Total Number of normals: 355.  


 

Somatic mutations of SELP:

 

Generating mutation plots.

 

Highly correlated genes for SELP:

 

Showing top 20/743 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SELPACKR10.78224311010
SELPMXD30.777936303
SELPZBTB330.738363303
SELPS1PR10.737376909
SELPSEMA6A0.711573303
SELPPIGS0.710489303
SELPHAVCR10.698035303
SELPARAF0.69548303
SELPCFH0.694977505
SELPGSN-AS10.69131303
SELPARHGEF70.689801303
SELPEMCN0.68587907
SELPXPNPEP20.685622807
SELPZNF100.685392303
SELPARHGAP150.682747403
SELPSPON10.682184605
SELPUBE2R20.681105303
SELPCLEC14A0.679553605
SELPSMOC20.677675505
SELPCD5L0.675574303

For details and further investigation, click here