| Full name: TUB bipartite transcription factor | Alias Symbol: rd5 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 7275 | HGNC ID: HGNC:12406 | Ensembl Gene: ENSG00000166402 | OMIM ID: 601197 |
| Drug and gene relationship at DGIdb | |||
Expression of TUB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUB | 7275 | 228882_at | -0.2575 | 0.7449 | |
| GSE20347 | TUB | 7275 | 210737_at | -0.1105 | 0.1356 | |
| GSE23400 | TUB | 7275 | 210737_at | -0.1268 | 0.0050 | |
| GSE26886 | TUB | 7275 | 210737_at | -0.0109 | 0.9346 | |
| GSE29001 | TUB | 7275 | 210737_at | -0.3261 | 0.0315 | |
| GSE38129 | TUB | 7275 | 210737_at | -0.1841 | 0.0385 | |
| GSE45670 | TUB | 7275 | 210737_at | 0.0238 | 0.7860 | |
| GSE53622 | TUB | 7275 | 34117 | -0.3817 | 0.0276 | |
| GSE53624 | TUB | 7275 | 34117 | -0.2040 | 0.2148 | |
| GSE63941 | TUB | 7275 | 210737_at | 0.2269 | 0.1078 | |
| GSE77861 | TUB | 7275 | 210737_at | 0.0045 | 0.9689 | |
| GSE97050 | TUB | 7275 | A_23_P500892 | -1.2541 | 0.1050 | |
| SRP007169 | TUB | 7275 | RNAseq | 0.7796 | 0.2930 | |
| SRP064894 | TUB | 7275 | RNAseq | -0.7593 | 0.0145 | |
| SRP133303 | TUB | 7275 | RNAseq | -0.8975 | 0.0017 | |
| SRP159526 | TUB | 7275 | RNAseq | 0.4004 | 0.2148 | |
| SRP193095 | TUB | 7275 | RNAseq | 0.2967 | 0.1778 | |
| SRP219564 | TUB | 7275 | RNAseq | 0.0562 | 0.8991 | |
| TCGA | TUB | 7275 | RNAseq | -0.2599 | 0.2093 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TUB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TUB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUB | 7275 | 0 | 11 | 19 | |
| GSE20123 | TUB | 7275 | 0 | 11 | 19 | |
| GSE43470 | TUB | 7275 | 2 | 6 | 35 | |
| GSE46452 | TUB | 7275 | 7 | 5 | 47 | |
| GSE47630 | TUB | 7275 | 2 | 12 | 26 | |
| GSE54993 | TUB | 7275 | 3 | 1 | 66 | |
| GSE54994 | TUB | 7275 | 2 | 12 | 39 | |
| GSE60625 | TUB | 7275 | 0 | 0 | 11 | |
| GSE74703 | TUB | 7275 | 1 | 5 | 30 | |
| GSE74704 | TUB | 7275 | 0 | 9 | 11 | |
| TCGA | TUB | 7275 | 9 | 36 | 51 |
Total number of gains: 26; Total number of losses: 108; Total Number of normals: 354.
Somatic mutations of TUB:
Generating mutation plots.
Highly correlated genes for TUB:
Showing top 20/839 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUB | SSTR4 | 0.774152 | 4 | 0 | 4 |
| TUB | RPL27A | 0.739676 | 3 | 0 | 3 |
| TUB | CGA | 0.738266 | 4 | 0 | 4 |
| TUB | TCP10L | 0.737395 | 4 | 0 | 4 |
| TUB | TLN2 | 0.734994 | 3 | 0 | 3 |
| TUB | SLC28A2 | 0.73135 | 5 | 0 | 5 |
| TUB | PDYN | 0.728283 | 4 | 0 | 4 |
| TUB | PHLDB1 | 0.726719 | 6 | 0 | 5 |
| TUB | CST3 | 0.726457 | 3 | 0 | 3 |
| TUB | GPR37L1 | 0.725285 | 5 | 0 | 5 |
| TUB | CHAD | 0.724747 | 4 | 0 | 4 |
| TUB | KRT38 | 0.72184 | 4 | 0 | 4 |
| TUB | SLC25A23 | 0.714675 | 3 | 0 | 3 |
| TUB | OPHN1 | 0.713716 | 4 | 0 | 3 |
| TUB | HOXA3 | 0.71142 | 6 | 0 | 5 |
| TUB | PRDM14 | 0.711097 | 4 | 0 | 4 |
| TUB | DCAKD | 0.709456 | 3 | 0 | 3 |
| TUB | BRINP2 | 0.707848 | 4 | 0 | 4 |
| TUB | DSCR4 | 0.707352 | 4 | 0 | 4 |
| TUB | HHLA1 | 0.705546 | 6 | 0 | 5 |
For details and further investigation, click here
