| Full name: zinc finger and BTB domain containing 7C | Alias Symbol: ZNF857C | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 201501 | HGNC ID: HGNC:31700 | Ensembl Gene: ENSG00000184828 | OMIM ID: 616591 |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB7C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB7C | 201501 | 227782_at | -1.6580 | 0.0399 | |
| GSE20347 | ZBTB7C | 201501 | 217675_at | -0.2463 | 0.0001 | |
| GSE23400 | ZBTB7C | 201501 | 217675_at | -0.1931 | 0.0000 | |
| GSE26886 | ZBTB7C | 201501 | 227782_at | -2.0625 | 0.0000 | |
| GSE29001 | ZBTB7C | 201501 | 217675_at | -0.1711 | 0.0797 | |
| GSE38129 | ZBTB7C | 201501 | 217675_at | -0.2107 | 0.0324 | |
| GSE45670 | ZBTB7C | 201501 | 227782_at | -1.0474 | 0.0148 | |
| GSE53622 | ZBTB7C | 201501 | 55737 | -2.1034 | 0.0000 | |
| GSE53624 | ZBTB7C | 201501 | 55737 | -1.9977 | 0.0000 | |
| GSE63941 | ZBTB7C | 201501 | 227782_at | 0.8325 | 0.2153 | |
| GSE77861 | ZBTB7C | 201501 | 227782_at | -0.7255 | 0.1542 | |
| GSE97050 | ZBTB7C | 201501 | A_33_P3402304 | -0.9879 | 0.1143 | |
| SRP007169 | ZBTB7C | 201501 | RNAseq | -2.7010 | 0.0000 | |
| SRP008496 | ZBTB7C | 201501 | RNAseq | -2.0160 | 0.0023 | |
| SRP064894 | ZBTB7C | 201501 | RNAseq | -1.9535 | 0.0000 | |
| SRP133303 | ZBTB7C | 201501 | RNAseq | -1.9327 | 0.0002 | |
| SRP159526 | ZBTB7C | 201501 | RNAseq | -0.3877 | 0.6781 | |
| SRP193095 | ZBTB7C | 201501 | RNAseq | -1.7746 | 0.0000 | |
| SRP219564 | ZBTB7C | 201501 | RNAseq | -2.4823 | 0.0038 | |
| TCGA | ZBTB7C | 201501 | RNAseq | -0.1339 | 0.4998 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by ZBTB7C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB7C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB7C | 201501 | 1 | 9 | 20 | |
| GSE20123 | ZBTB7C | 201501 | 1 | 8 | 21 | |
| GSE43470 | ZBTB7C | 201501 | 0 | 5 | 38 | |
| GSE46452 | ZBTB7C | 201501 | 1 | 26 | 32 | |
| GSE47630 | ZBTB7C | 201501 | 5 | 20 | 15 | |
| GSE54993 | ZBTB7C | 201501 | 9 | 0 | 61 | |
| GSE54994 | ZBTB7C | 201501 | 2 | 16 | 35 | |
| GSE60625 | ZBTB7C | 201501 | 0 | 4 | 7 | |
| GSE74703 | ZBTB7C | 201501 | 0 | 4 | 32 | |
| GSE74704 | ZBTB7C | 201501 | 0 | 6 | 14 | |
| TCGA | ZBTB7C | 201501 | 13 | 41 | 42 |
Total number of gains: 32; Total number of losses: 139; Total Number of normals: 317.
Somatic mutations of ZBTB7C:
Generating mutation plots.
Highly correlated genes for ZBTB7C:
Showing top 20/1303 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB7C | C5orf66-AS1 | 0.787622 | 6 | 0 | 6 |
| ZBTB7C | FAM3B | 0.776947 | 7 | 0 | 6 |
| ZBTB7C | SMIM5 | 0.774182 | 6 | 0 | 6 |
| ZBTB7C | USP54 | 0.773149 | 6 | 0 | 6 |
| ZBTB7C | ST6GALNAC1 | 0.771718 | 7 | 0 | 7 |
| ZBTB7C | SH3BGRL2 | 0.766271 | 7 | 0 | 7 |
| ZBTB7C | FAM3D | 0.751679 | 8 | 0 | 7 |
| ZBTB7C | CXCL17 | 0.74818 | 7 | 0 | 7 |
| ZBTB7C | FAM214A | 0.74794 | 6 | 0 | 6 |
| ZBTB7C | MUC20 | 0.74577 | 7 | 0 | 7 |
| ZBTB7C | KRT78 | 0.745322 | 7 | 0 | 7 |
| ZBTB7C | ATP13A4 | 0.736358 | 8 | 0 | 7 |
| ZBTB7C | TMPRSS11B | 0.736268 | 7 | 0 | 7 |
| ZBTB7C | MUC15 | 0.735959 | 7 | 0 | 7 |
| ZBTB7C | ULK3 | 0.735806 | 6 | 0 | 6 |
| ZBTB7C | FLG-AS1 | 0.73488 | 5 | 0 | 5 |
| ZBTB7C | NCCRP1 | 0.723873 | 3 | 0 | 3 |
| ZBTB7C | TPRG1 | 0.721525 | 7 | 0 | 7 |
| ZBTB7C | PRSS27 | 0.718338 | 7 | 0 | 7 |
| ZBTB7C | CYP2C9 | 0.71774 | 10 | 0 | 10 |
For details and further investigation, click here
