| Full name: ring finger protein 170 | Alias Symbol: DKFZP564A022|ADSA | ||
| Type: protein-coding gene | Cytoband: 8p11.21 | ||
| Entrez ID: 81790 | HGNC ID: HGNC:25358 | Ensembl Gene: ENSG00000120925 | OMIM ID: 614649 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF170:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF170 | 81790 | 226104_at | -0.1290 | 0.8644 | |
| GSE20347 | RNF170 | 81790 | 220985_s_at | -0.7948 | 0.0000 | |
| GSE23400 | RNF170 | 81790 | 220985_s_at | -0.1722 | 0.0352 | |
| GSE26886 | RNF170 | 81790 | 220985_s_at | -2.2223 | 0.0000 | |
| GSE29001 | RNF170 | 81790 | 220985_s_at | -0.5669 | 0.2609 | |
| GSE38129 | RNF170 | 81790 | 220985_s_at | -0.2515 | 0.2976 | |
| GSE45670 | RNF170 | 81790 | 226104_at | -0.2475 | 0.1225 | |
| GSE53622 | RNF170 | 81790 | 127423 | -0.1711 | 0.0830 | |
| GSE53624 | RNF170 | 81790 | 127423 | -0.7034 | 0.0000 | |
| GSE63941 | RNF170 | 81790 | 220985_s_at | -0.9132 | 0.0236 | |
| GSE77861 | RNF170 | 81790 | 226104_at | -0.6339 | 0.1487 | |
| GSE97050 | RNF170 | 81790 | A_23_P146209 | 0.1087 | 0.8438 | |
| SRP007169 | RNF170 | 81790 | RNAseq | -1.5790 | 0.0001 | |
| SRP008496 | RNF170 | 81790 | RNAseq | -1.3858 | 0.0000 | |
| SRP064894 | RNF170 | 81790 | RNAseq | -0.4243 | 0.0471 | |
| SRP133303 | RNF170 | 81790 | RNAseq | -0.2179 | 0.2676 | |
| SRP159526 | RNF170 | 81790 | RNAseq | -0.9008 | 0.0001 | |
| SRP193095 | RNF170 | 81790 | RNAseq | -0.7935 | 0.0000 | |
| SRP219564 | RNF170 | 81790 | RNAseq | -0.7269 | 0.0383 | |
| TCGA | RNF170 | 81790 | RNAseq | -0.0445 | 0.5045 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RNF170 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF170:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF170 | 81790 | 10 | 4 | 16 | |
| GSE20123 | RNF170 | 81790 | 10 | 4 | 16 | |
| GSE43470 | RNF170 | 81790 | 8 | 6 | 29 | |
| GSE46452 | RNF170 | 81790 | 19 | 5 | 35 | |
| GSE47630 | RNF170 | 81790 | 22 | 1 | 17 | |
| GSE54993 | RNF170 | 81790 | 1 | 16 | 53 | |
| GSE54994 | RNF170 | 81790 | 18 | 8 | 27 | |
| GSE60625 | RNF170 | 81790 | 3 | 0 | 8 | |
| GSE74703 | RNF170 | 81790 | 7 | 5 | 24 | |
| GSE74704 | RNF170 | 81790 | 9 | 1 | 10 | |
| TCGA | RNF170 | 81790 | 38 | 21 | 37 |
Total number of gains: 145; Total number of losses: 71; Total Number of normals: 272.
Somatic mutations of RNF170:
Generating mutation plots.
Highly correlated genes for RNF170:
Showing top 20/793 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF170 | FDXR | 0.68005 | 4 | 0 | 4 |
| RNF170 | CNN3 | 0.675222 | 5 | 0 | 5 |
| RNF170 | MFAP3 | 0.663022 | 6 | 0 | 5 |
| RNF170 | GRHL3 | 0.659848 | 4 | 0 | 3 |
| RNF170 | WDFY1 | 0.659712 | 5 | 0 | 4 |
| RNF170 | FAM135A | 0.657294 | 4 | 0 | 3 |
| RNF170 | GID8 | 0.65575 | 5 | 0 | 4 |
| RNF170 | TCAIM | 0.652549 | 5 | 0 | 4 |
| RNF170 | ORMDL2 | 0.651868 | 7 | 0 | 5 |
| RNF170 | RTCA | 0.649763 | 6 | 0 | 5 |
| RNF170 | CMTR2 | 0.649392 | 5 | 0 | 4 |
| RNF170 | KCTD9 | 0.647578 | 6 | 0 | 5 |
| RNF170 | TM9SF3 | 0.647315 | 6 | 0 | 6 |
| RNF170 | FAM219B | 0.644074 | 3 | 0 | 3 |
| RNF170 | GBP6 | 0.643577 | 3 | 0 | 3 |
| RNF170 | UBE2K | 0.643576 | 8 | 0 | 6 |
| RNF170 | CARHSP1 | 0.64338 | 6 | 0 | 5 |
| RNF170 | ITCH | 0.643098 | 7 | 0 | 6 |
| RNF170 | COMMD8 | 0.641687 | 11 | 0 | 8 |
| RNF170 | UBAC2 | 0.638744 | 3 | 0 | 3 |
For details and further investigation, click here
