| Full name: transmembrane protein 14C | Alias Symbol: HSPC194|bA421M1.6|NET26 | ||
| Type: protein-coding gene | Cytoband: 6p24.2 | ||
| Entrez ID: 51522 | HGNC ID: HGNC:20952 | Ensembl Gene: ENSG00000111843 | OMIM ID: 615318 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM14C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM14C | 51522 | 223106_at | -0.2672 | 0.4059 | |
| GSE26886 | TMEM14C | 51522 | 223106_at | -0.5257 | 0.0430 | |
| GSE45670 | TMEM14C | 51522 | 223106_at | -0.3321 | 0.0224 | |
| GSE53622 | TMEM14C | 51522 | 88597 | 0.0899 | 0.1245 | |
| GSE53624 | TMEM14C | 51522 | 88597 | 0.1170 | 0.0824 | |
| GSE63941 | TMEM14C | 51522 | 223106_at | -0.5924 | 0.1121 | |
| GSE77861 | TMEM14C | 51522 | 223106_at | -0.3496 | 0.3160 | |
| GSE97050 | TMEM14C | 51522 | A_33_P3402500 | -0.1172 | 0.5462 | |
| SRP007169 | TMEM14C | 51522 | RNAseq | -0.8601 | 0.0225 | |
| SRP008496 | TMEM14C | 51522 | RNAseq | -0.6457 | 0.0005 | |
| SRP064894 | TMEM14C | 51522 | RNAseq | 0.0167 | 0.9427 | |
| SRP133303 | TMEM14C | 51522 | RNAseq | -0.0481 | 0.7630 | |
| SRP159526 | TMEM14C | 51522 | RNAseq | 0.0339 | 0.8753 | |
| SRP193095 | TMEM14C | 51522 | RNAseq | -0.6755 | 0.0000 | |
| SRP219564 | TMEM14C | 51522 | RNAseq | -0.2721 | 0.4599 | |
| TCGA | TMEM14C | 51522 | RNAseq | -0.0449 | 0.4545 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM14C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM14C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM14C | 51522 | 4 | 7 | 19 | |
| GSE20123 | TMEM14C | 51522 | 4 | 7 | 19 | |
| GSE43470 | TMEM14C | 51522 | 8 | 2 | 33 | |
| GSE46452 | TMEM14C | 51522 | 1 | 10 | 48 | |
| GSE47630 | TMEM14C | 51522 | 7 | 8 | 25 | |
| GSE54993 | TMEM14C | 51522 | 1 | 1 | 68 | |
| GSE54994 | TMEM14C | 51522 | 10 | 3 | 40 | |
| GSE60625 | TMEM14C | 51522 | 0 | 1 | 10 | |
| GSE74703 | TMEM14C | 51522 | 7 | 2 | 27 | |
| GSE74704 | TMEM14C | 51522 | 2 | 3 | 15 | |
| TCGA | TMEM14C | 51522 | 15 | 28 | 53 |
Total number of gains: 59; Total number of losses: 72; Total Number of normals: 357.
Somatic mutations of TMEM14C:
Generating mutation plots.
Highly correlated genes for TMEM14C:
Showing top 20/203 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM14C | RWDD2B | 0.693297 | 3 | 0 | 3 |
| TMEM14C | TMEM126A | 0.689228 | 4 | 0 | 3 |
| TMEM14C | C16orf72 | 0.68521 | 3 | 0 | 3 |
| TMEM14C | FASTKD2 | 0.672296 | 3 | 0 | 3 |
| TMEM14C | MNS1 | 0.67067 | 3 | 0 | 3 |
| TMEM14C | SNAPIN | 0.655357 | 3 | 0 | 3 |
| TMEM14C | PRPF18 | 0.654615 | 4 | 0 | 4 |
| TMEM14C | EEA1 | 0.635309 | 4 | 0 | 4 |
| TMEM14C | CRY2 | 0.635283 | 3 | 0 | 3 |
| TMEM14C | CAPN7 | 0.628013 | 5 | 0 | 5 |
| TMEM14C | NDUFS1 | 0.627486 | 3 | 0 | 3 |
| TMEM14C | VAPA | 0.626422 | 3 | 0 | 3 |
| TMEM14C | PRDM4 | 0.625594 | 3 | 0 | 3 |
| TMEM14C | APC | 0.621209 | 4 | 0 | 3 |
| TMEM14C | SH3BGRL | 0.620911 | 3 | 0 | 3 |
| TMEM14C | TWF1 | 0.617951 | 3 | 0 | 3 |
| TMEM14C | LTN1 | 0.617365 | 5 | 0 | 3 |
| TMEM14C | SSBP1 | 0.615264 | 4 | 0 | 3 |
| TMEM14C | RAF1 | 0.614365 | 5 | 0 | 4 |
| TMEM14C | SGMS2 | 0.613704 | 4 | 0 | 3 |
For details and further investigation, click here
