TMEM251

 

Full name: transmembrane protein 251 Alias Symbol: DKFZP564F1123
Type: protein-coding gene Cytoband: 14q32.12
Entrez ID: 26175 HGNC ID: HGNC:20218 Ensembl Gene: ENSG00000153485 OMIM ID: 
Screen Evidence:

 

Expression of TMEM251:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM251 26175 213246_at 0.3949 0.2841
GSE20347 TMEM251 26175 213246_at 0.6028 0.0513
GSE23400 TMEM251 26175 213246_at 0.9803 0.0000
GSE26886 TMEM251 26175 213246_at 0.0748 0.7980
GSE29001 TMEM251 26175 213246_at 1.0524 0.0174
GSE38129 TMEM251 26175 213246_at 0.6655 0.0072
GSE45670 TMEM251 26175 213246_at 0.4973 0.0309
GSE53622 TMEM251 26175 54378 0.6419 0.0000
GSE53624 TMEM251 26175 54378 0.6827 0.0000
GSE63941 TMEM251 26175 213246_at 1.1643 0.0179
GSE77861 TMEM251 26175 213246_at 0.7918 0.0805
SRP007169 TMEM251 26175 RNAseq 1.1542 0.0181
SRP008496 TMEM251 26175 RNAseq 0.9148 0.0247
SRP064894 TMEM251 26175 RNAseq 0.6710 0.0005
SRP133303 TMEM251 26175 RNAseq 0.7128 0.0000
SRP159526 TMEM251 26175 RNAseq 0.6671 0.0343
SRP193095 TMEM251 26175 RNAseq 0.4138 0.0001
SRP219564 TMEM251 26175 RNAseq 0.4378 0.2185

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by TMEM251 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of TMEM251:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM251 26175 8 5 17
GSE20123 TMEM251 26175 8 4 18
GSE43470 TMEM251 26175 7 3 33
GSE46452 TMEM251 26175 16 3 40
GSE47630 TMEM251 26175 11 8 21
GSE54993 TMEM251 26175 3 8 59
GSE54994 TMEM251 26175 20 4 29
GSE60625 TMEM251 26175 0 2 9
GSE74703 TMEM251 26175 6 3 27
GSE74704 TMEM251 26175 4 3 13
TCGA TMEM251 26175 29 21 46

Total number of gains: 112; Total number of losses: 64; Total Number of normals: 312.  

 

Somatic mutations of TMEM251:

 

Generating mutation plots.

 

Highly correlated genes for TMEM251:

 

Showing top 20/956 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM251PSMC10.748653909
TMEM251LRR10.733578404
TMEM251UBTD20.716554303
TMEM251SLC7A6OS0.708488303
TMEM251SLC38A60.70772707
TMEM251TSN0.699086909
TMEM251MNAT10.6969511009
TMEM251MGAT20.692515606
TMEM251ERH0.68912510010
TMEM251GLRX50.6817181109
TMEM251ADSL0.681585909
TMEM251EMG10.67927606
TMEM251HAT10.677482908
TMEM251ATP6V1C10.668993908
TMEM251THOC50.667331807
TMEM251ILF20.6662791008
TMEM251PSMB50.66481807
TMEM251PSMA30.66338511010
TMEM251L3HYPDH0.660592606
TMEM251ALKBH10.6598941008

For details and further investigation, click here