| Full name: AHNAK nucleoprotein | Alias Symbol: MGC5395 | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 79026 | HGNC ID: HGNC:347 | Ensembl Gene: ENSG00000124942 | OMIM ID: 103390 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of AHNAK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AHNAK | 79026 | 211986_at | -1.0517 | 0.0289 | |
| GSE20347 | AHNAK | 79026 | 211986_at | -1.3963 | 0.0000 | |
| GSE23400 | AHNAK | 79026 | 211986_at | -0.9051 | 0.0000 | |
| GSE26886 | AHNAK | 79026 | 211986_at | -1.6368 | 0.0000 | |
| GSE29001 | AHNAK | 79026 | 211986_at | -1.3916 | 0.0012 | |
| GSE38129 | AHNAK | 79026 | 211986_at | -1.3113 | 0.0000 | |
| GSE45670 | AHNAK | 79026 | 211986_at | -0.7820 | 0.0000 | |
| GSE53622 | AHNAK | 79026 | 12391 | -1.7005 | 0.0000 | |
| GSE53624 | AHNAK | 79026 | 67733 | -1.5866 | 0.0000 | |
| GSE63941 | AHNAK | 79026 | 211986_at | -1.1319 | 0.0649 | |
| GSE77861 | AHNAK | 79026 | 211986_at | -0.4284 | 0.0703 | |
| GSE97050 | AHNAK | 79026 | A_24_P943393 | -1.5432 | 0.0454 | |
| SRP007169 | AHNAK | 79026 | RNAseq | -1.1518 | 0.0060 | |
| SRP008496 | AHNAK | 79026 | RNAseq | -1.0415 | 0.0003 | |
| SRP064894 | AHNAK | 79026 | RNAseq | -1.8175 | 0.0000 | |
| SRP133303 | AHNAK | 79026 | RNAseq | -1.3485 | 0.0000 | |
| SRP159526 | AHNAK | 79026 | RNAseq | -1.9298 | 0.0001 | |
| SRP193095 | AHNAK | 79026 | RNAseq | -1.3418 | 0.0000 | |
| SRP219564 | AHNAK | 79026 | RNAseq | -1.5609 | 0.0007 | |
| TCGA | AHNAK | 79026 | RNAseq | -0.1677 | 0.0077 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by AHNAK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AHNAK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AHNAK | 79026 | 6 | 5 | 19 | |
| GSE20123 | AHNAK | 79026 | 6 | 5 | 19 | |
| GSE43470 | AHNAK | 79026 | 2 | 6 | 35 | |
| GSE46452 | AHNAK | 79026 | 8 | 4 | 47 | |
| GSE47630 | AHNAK | 79026 | 3 | 7 | 30 | |
| GSE54993 | AHNAK | 79026 | 3 | 0 | 67 | |
| GSE54994 | AHNAK | 79026 | 4 | 5 | 44 | |
| GSE60625 | AHNAK | 79026 | 0 | 3 | 8 | |
| GSE74703 | AHNAK | 79026 | 2 | 3 | 31 | |
| GSE74704 | AHNAK | 79026 | 4 | 3 | 13 | |
| TCGA | AHNAK | 79026 | 15 | 12 | 69 |
Total number of gains: 53; Total number of losses: 53; Total Number of normals: 382.
Somatic mutations of AHNAK:
Generating mutation plots.
Highly correlated genes for AHNAK:
Showing top 20/1483 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AHNAK | MYZAP | 0.811097 | 3 | 0 | 3 |
| AHNAK | PTK6 | 0.778556 | 10 | 0 | 10 |
| AHNAK | PDLIM2 | 0.768933 | 9 | 0 | 8 |
| AHNAK | DOCK9 | 0.764707 | 10 | 0 | 10 |
| AHNAK | MGLL | 0.76237 | 12 | 0 | 11 |
| AHNAK | LRP10 | 0.760911 | 11 | 0 | 10 |
| AHNAK | CYSRT1 | 0.759925 | 6 | 0 | 5 |
| AHNAK | MTMR10 | 0.759408 | 6 | 0 | 6 |
| AHNAK | PPL | 0.756959 | 11 | 0 | 11 |
| AHNAK | TP53I3 | 0.754108 | 10 | 0 | 10 |
| AHNAK | ZFAND2B | 0.75231 | 6 | 0 | 6 |
| AHNAK | LGALS3 | 0.751533 | 12 | 0 | 12 |
| AHNAK | KRT4 | 0.751221 | 10 | 0 | 10 |
| AHNAK | CAPN14 | 0.750846 | 6 | 0 | 6 |
| AHNAK | MAL | 0.749407 | 11 | 0 | 10 |
| AHNAK | NPEPPS | 0.749077 | 10 | 0 | 10 |
| AHNAK | IL1RN | 0.747907 | 10 | 0 | 10 |
| AHNAK | GPD1L | 0.747552 | 10 | 0 | 9 |
| AHNAK | SNORA68 | 0.747222 | 4 | 0 | 4 |
| AHNAK | RSPH3 | 0.747175 | 3 | 0 | 3 |
For details and further investigation, click here
