| Full name: cytochrome c oxidase assembly factor 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q42.2 | ||
| Entrez ID: 388753 | HGNC ID: HGNC:18025 | Ensembl Gene: ENSG00000168275 | OMIM ID: 614772 |
Screen Evidence:
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Expression of COA6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COA6 | 388753 | 225638_at | 0.9245 | 0.0539 | |
| GSE26886 | COA6 | 388753 | 225638_at | 0.7747 | 0.0003 | |
| GSE45670 | COA6 | 388753 | 225638_at | 0.7985 | 0.0053 | |
| GSE53622 | COA6 | 388753 | 1106 | 0.8520 | 0.0000 | |
| GSE53624 | COA6 | 388753 | 1106 | 1.1734 | 0.0000 | |
| GSE63941 | COA6 | 388753 | 225638_at | 1.5695 | 0.0131 | |
| GSE77861 | COA6 | 388753 | 225638_at | 1.0417 | 0.0049 | |
| SRP007169 | COA6 | 388753 | RNAseq | 0.9392 | 0.0963 | |
| SRP008496 | COA6 | 388753 | RNAseq | 0.9768 | 0.0164 | |
| SRP064894 | COA6 | 388753 | RNAseq | 0.9859 | 0.0002 | |
| SRP133303 | COA6 | 388753 | RNAseq | 1.1601 | 0.0000 | |
| SRP159526 | COA6 | 388753 | RNAseq | 1.7048 | 0.0115 | |
| SRP193095 | COA6 | 388753 | RNAseq | 0.5473 | 0.0105 | |
| SRP219564 | COA6 | 388753 | RNAseq | 0.8429 | 0.0551 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by COA6 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of COA6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COA6 | 388753 | 10 | 0 | 20 | |
| GSE20123 | COA6 | 388753 | 11 | 0 | 19 | |
| GSE43470 | COA6 | 388753 | 9 | 0 | 34 | |
| GSE46452 | COA6 | 388753 | 4 | 2 | 53 | |
| GSE47630 | COA6 | 388753 | 15 | 0 | 25 | |
| GSE54993 | COA6 | 388753 | 0 | 6 | 64 | |
| GSE54994 | COA6 | 388753 | 16 | 0 | 37 | |
| GSE60625 | COA6 | 388753 | 0 | 0 | 11 | |
| GSE74703 | COA6 | 388753 | 9 | 0 | 27 | |
| GSE74704 | COA6 | 388753 | 5 | 0 | 15 | |
| TCGA | COA6 | 388753 | 44 | 3 | 49 |
Total number of gains: 123; Total number of losses: 11; Total Number of normals: 354.
Somatic mutations of COA6:
Generating mutation plots.
Highly correlated genes for COA6:
Showing top 20/1201 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COA6 | C1orf131 | 0.773077 | 7 | 0 | 7 |
| COA6 | TXNRD1 | 0.772943 | 6 | 0 | 6 |
| COA6 | ZC3H18 | 0.764268 | 3 | 0 | 3 |
| COA6 | HEATR1 | 0.76395 | 7 | 0 | 7 |
| COA6 | GLA | 0.752695 | 6 | 0 | 6 |
| COA6 | DDX39A | 0.735166 | 7 | 0 | 7 |
| COA6 | LRP12 | 0.730003 | 6 | 0 | 6 |
| COA6 | CABYR | 0.724403 | 5 | 0 | 5 |
| COA6 | FUT1 | 0.71874 | 4 | 0 | 4 |
| COA6 | LRP8 | 0.718712 | 4 | 0 | 4 |
| COA6 | CDCA3 | 0.718614 | 5 | 0 | 5 |
| COA6 | ODC1 | 0.718058 | 6 | 0 | 6 |
| COA6 | CCT3 | 0.7177 | 6 | 0 | 6 |
| COA6 | PSMD14 | 0.717339 | 6 | 0 | 6 |
| COA6 | TBCE | 0.714851 | 5 | 0 | 5 |
| COA6 | UBE2T | 0.713203 | 7 | 0 | 7 |
| COA6 | FBRSL1 | 0.707394 | 4 | 0 | 4 |
| COA6 | CCDC86 | 0.705592 | 5 | 0 | 4 |
| COA6 | SNRPG | 0.701612 | 6 | 0 | 6 |
| COA6 | OR51E1 | 0.700234 | 3 | 0 | 3 |
For details and further investigation, click here
