| Full name: TRAF-type zinc finger domain containing 1 | Alias Symbol: FLN29 | ||
| Type: protein-coding gene | Cytoband: 12q24.13 | ||
| Entrez ID: 10906 | HGNC ID: HGNC:24808 | Ensembl Gene: ENSG00000135148 | OMIM ID: 613197 |
| Drug and gene relationship at DGIdb | |||
Expression of TRAFD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAFD1 | 10906 | 35254_at | -0.1597 | 0.7711 | |
| GSE20347 | TRAFD1 | 10906 | 35254_at | -0.2423 | 0.0281 | |
| GSE23400 | TRAFD1 | 10906 | 35254_at | 0.0249 | 0.5418 | |
| GSE26886 | TRAFD1 | 10906 | 35254_at | -1.1161 | 0.0001 | |
| GSE29001 | TRAFD1 | 10906 | 35254_at | -0.0510 | 0.9161 | |
| GSE38129 | TRAFD1 | 10906 | 35254_at | -0.1587 | 0.1094 | |
| GSE45670 | TRAFD1 | 10906 | 35254_at | 0.2696 | 0.1458 | |
| GSE53622 | TRAFD1 | 10906 | 39186 | -0.2011 | 0.0059 | |
| GSE53624 | TRAFD1 | 10906 | 39186 | -0.2545 | 0.0001 | |
| GSE63941 | TRAFD1 | 10906 | 35254_at | 0.1545 | 0.8282 | |
| GSE77861 | TRAFD1 | 10906 | 35254_at | -0.3444 | 0.0860 | |
| GSE97050 | TRAFD1 | 10906 | A_33_P3372124 | 0.0470 | 0.8525 | |
| SRP007169 | TRAFD1 | 10906 | RNAseq | -1.2032 | 0.0006 | |
| SRP008496 | TRAFD1 | 10906 | RNAseq | -1.0735 | 0.0000 | |
| SRP064894 | TRAFD1 | 10906 | RNAseq | -0.4570 | 0.0000 | |
| SRP133303 | TRAFD1 | 10906 | RNAseq | -0.2224 | 0.2988 | |
| SRP159526 | TRAFD1 | 10906 | RNAseq | -0.0115 | 0.9705 | |
| SRP193095 | TRAFD1 | 10906 | RNAseq | -0.5386 | 0.0000 | |
| SRP219564 | TRAFD1 | 10906 | RNAseq | -0.4494 | 0.1425 | |
| TCGA | TRAFD1 | 10906 | RNAseq | 0.1444 | 0.0073 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TRAFD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRAFD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAFD1 | 10906 | 5 | 3 | 22 | |
| GSE20123 | TRAFD1 | 10906 | 5 | 3 | 22 | |
| GSE43470 | TRAFD1 | 10906 | 2 | 1 | 40 | |
| GSE46452 | TRAFD1 | 10906 | 9 | 1 | 49 | |
| GSE47630 | TRAFD1 | 10906 | 9 | 3 | 28 | |
| GSE54993 | TRAFD1 | 10906 | 0 | 5 | 65 | |
| GSE54994 | TRAFD1 | 10906 | 4 | 2 | 47 | |
| GSE60625 | TRAFD1 | 10906 | 0 | 0 | 11 | |
| GSE74703 | TRAFD1 | 10906 | 2 | 0 | 34 | |
| GSE74704 | TRAFD1 | 10906 | 2 | 2 | 16 | |
| TCGA | TRAFD1 | 10906 | 22 | 11 | 63 |
Total number of gains: 60; Total number of losses: 31; Total Number of normals: 397.
Somatic mutations of TRAFD1:
Generating mutation plots.
Highly correlated genes for TRAFD1:
Showing top 20/650 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAFD1 | RAB35 | 0.788215 | 3 | 0 | 3 |
| TRAFD1 | PRPF38A | 0.780597 | 3 | 0 | 3 |
| TRAFD1 | HGF | 0.75939 | 3 | 0 | 3 |
| TRAFD1 | CELA3A | 0.755276 | 3 | 0 | 3 |
| TRAFD1 | PPP1R8 | 0.720041 | 3 | 0 | 3 |
| TRAFD1 | TCHP | 0.719007 | 3 | 0 | 3 |
| TRAFD1 | CD59 | 0.710065 | 3 | 0 | 3 |
| TRAFD1 | IER3IP1 | 0.70482 | 3 | 0 | 3 |
| TRAFD1 | UBE3C | 0.702992 | 3 | 0 | 3 |
| TRAFD1 | SUPT4H1 | 0.701983 | 4 | 0 | 4 |
| TRAFD1 | SLC9A9 | 0.698916 | 4 | 0 | 3 |
| TRAFD1 | PPP1CC | 0.697182 | 3 | 0 | 3 |
| TRAFD1 | WDR37 | 0.694759 | 3 | 0 | 3 |
| TRAFD1 | ZNF436 | 0.691251 | 4 | 0 | 4 |
| TRAFD1 | MKRN1 | 0.685275 | 4 | 0 | 4 |
| TRAFD1 | KCTD10 | 0.685223 | 3 | 0 | 3 |
| TRAFD1 | C11orf45 | 0.684273 | 4 | 0 | 3 |
| TRAFD1 | DCTD | 0.6841 | 4 | 0 | 4 |
| TRAFD1 | ZNF175 | 0.679402 | 3 | 0 | 3 |
| TRAFD1 | ZNF681 | 0.677655 | 3 | 0 | 3 |
For details and further investigation, click here
