| Full name: solute carrier family 39 member 7 | Alias Symbol: H2-KE4|D6S2244E|KE4|RING5|ZIP7 | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 7922 | HGNC ID: HGNC:4927 | Ensembl Gene: ENSG00000112473 | OMIM ID: 601416 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC39A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC39A7 | 7922 | 202667_s_at | 0.6327 | 0.1439 | |
| GSE20347 | SLC39A7 | 7922 | 202667_s_at | 0.1805 | 0.0532 | |
| GSE23400 | SLC39A7 | 7922 | 202667_s_at | 0.4990 | 0.0000 | |
| GSE26886 | SLC39A7 | 7922 | 202667_s_at | -0.7634 | 0.0000 | |
| GSE29001 | SLC39A7 | 7922 | 202667_s_at | 0.6083 | 0.1970 | |
| GSE38129 | SLC39A7 | 7922 | 202667_s_at | 0.5662 | 0.0591 | |
| GSE45670 | SLC39A7 | 7922 | 202667_s_at | 0.5499 | 0.0005 | |
| GSE53622 | SLC39A7 | 7922 | 116194 | 0.4967 | 0.0000 | |
| GSE53624 | SLC39A7 | 7922 | 116194 | 0.4774 | 0.0000 | |
| GSE63941 | SLC39A7 | 7922 | 202667_s_at | -1.0061 | 0.0398 | |
| GSE77861 | SLC39A7 | 7922 | 202667_s_at | 0.0725 | 0.7996 | |
| GSE97050 | SLC39A7 | 7922 | A_23_P70571 | 0.5431 | 0.1470 | |
| SRP007169 | SLC39A7 | 7922 | RNAseq | 0.8663 | 0.0224 | |
| SRP008496 | SLC39A7 | 7922 | RNAseq | 0.7842 | 0.0020 | |
| SRP064894 | SLC39A7 | 7922 | RNAseq | 0.8442 | 0.0005 | |
| SRP133303 | SLC39A7 | 7922 | RNAseq | 0.7440 | 0.0000 | |
| SRP159526 | SLC39A7 | 7922 | RNAseq | 0.7019 | 0.0001 | |
| SRP193095 | SLC39A7 | 7922 | RNAseq | 0.2437 | 0.1798 | |
| SRP219564 | SLC39A7 | 7922 | RNAseq | 0.7056 | 0.0582 | |
| TCGA | SLC39A7 | 7922 | RNAseq | -0.0919 | 0.0422 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC39A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC39A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC39A7 | 7922 | 5 | 0 | 25 | |
| GSE20123 | SLC39A7 | 7922 | 5 | 0 | 25 | |
| GSE43470 | SLC39A7 | 7922 | 4 | 1 | 38 | |
| GSE46452 | SLC39A7 | 7922 | 2 | 9 | 48 | |
| GSE47630 | SLC39A7 | 7922 | 8 | 4 | 28 | |
| GSE54993 | SLC39A7 | 7922 | 3 | 1 | 66 | |
| GSE54994 | SLC39A7 | 7922 | 11 | 4 | 38 | |
| GSE60625 | SLC39A7 | 7922 | 1 | 0 | 10 | |
| GSE74703 | SLC39A7 | 7922 | 4 | 0 | 32 | |
| GSE74704 | SLC39A7 | 7922 | 2 | 0 | 18 | |
| TCGA | SLC39A7 | 7922 | 15 | 16 | 65 |
Total number of gains: 60; Total number of losses: 35; Total Number of normals: 393.
Somatic mutations of SLC39A7:
Generating mutation plots.
Highly correlated genes for SLC39A7:
Showing top 20/514 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC39A7 | SLC35B2 | 0.78316 | 3 | 0 | 3 |
| SLC39A7 | TBCD | 0.779881 | 3 | 0 | 3 |
| SLC39A7 | PDIA5 | 0.759579 | 3 | 0 | 3 |
| SLC39A7 | PRDM15 | 0.727505 | 3 | 0 | 3 |
| SLC39A7 | CREB3L2 | 0.727303 | 3 | 0 | 3 |
| SLC39A7 | KTI12 | 0.723225 | 3 | 0 | 3 |
| SLC39A7 | HGS | 0.722948 | 3 | 0 | 3 |
| SLC39A7 | ATF6B | 0.708424 | 4 | 0 | 4 |
| SLC39A7 | PRR13 | 0.703499 | 3 | 0 | 3 |
| SLC39A7 | FASN | 0.69958 | 3 | 0 | 3 |
| SLC39A7 | SMARCC1 | 0.6979 | 3 | 0 | 3 |
| SLC39A7 | PDIA4 | 0.6911 | 9 | 0 | 8 |
| SLC39A7 | ZNF468 | 0.683309 | 3 | 0 | 3 |
| SLC39A7 | MRPL12 | 0.680473 | 4 | 0 | 4 |
| SLC39A7 | PPP1R37 | 0.680323 | 3 | 0 | 3 |
| SLC39A7 | URM1 | 0.67399 | 3 | 0 | 3 |
| SLC39A7 | CDK10 | 0.673167 | 3 | 0 | 3 |
| SLC39A7 | DONSON | 0.669721 | 4 | 0 | 3 |
| SLC39A7 | TAF15 | 0.669006 | 4 | 0 | 4 |
| SLC39A7 | SMARCD2 | 0.668256 | 5 | 0 | 5 |
For details and further investigation, click here
