| Full name: proline rich 22 | Alias Symbol: MGC24975 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 163154 | HGNC ID: HGNC:28354 | Ensembl Gene: ENSG00000212123 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PRR22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR22 | 163154 | 1552272_a_at | 0.0766 | 0.8724 | |
| GSE26886 | PRR22 | 163154 | 1552271_at | -0.0436 | 0.7850 | |
| GSE45670 | PRR22 | 163154 | 1552271_at | -0.0744 | 0.4890 | |
| GSE53622 | PRR22 | 163154 | 84030 | -0.3332 | 0.1395 | |
| GSE53624 | PRR22 | 163154 | 84030 | 0.0041 | 0.9762 | |
| GSE63941 | PRR22 | 163154 | 1552271_at | 0.4109 | 0.0093 | |
| GSE77861 | PRR22 | 163154 | 1552271_at | -0.0423 | 0.7559 | |
| SRP064894 | PRR22 | 163154 | RNAseq | -0.0855 | 0.7966 | |
| SRP133303 | PRR22 | 163154 | RNAseq | -0.4902 | 0.3091 | |
| SRP159526 | PRR22 | 163154 | RNAseq | 0.1596 | 0.6782 | |
| SRP219564 | PRR22 | 163154 | RNAseq | 0.7416 | 0.1675 | |
| TCGA | PRR22 | 163154 | RNAseq | 0.0710 | 0.7135 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRR22 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR22 | 163154 | 5 | 3 | 22 | |
| GSE20123 | PRR22 | 163154 | 4 | 2 | 24 | |
| GSE43470 | PRR22 | 163154 | 2 | 6 | 35 | |
| GSE46452 | PRR22 | 163154 | 47 | 1 | 11 | |
| GSE47630 | PRR22 | 163154 | 5 | 7 | 28 | |
| GSE54993 | PRR22 | 163154 | 16 | 3 | 51 | |
| GSE54994 | PRR22 | 163154 | 6 | 16 | 31 | |
| GSE60625 | PRR22 | 163154 | 9 | 0 | 2 | |
| GSE74703 | PRR22 | 163154 | 2 | 4 | 30 | |
| GSE74704 | PRR22 | 163154 | 1 | 2 | 17 | |
| TCGA | PRR22 | 163154 | 10 | 17 | 69 |
Total number of gains: 107; Total number of losses: 61; Total Number of normals: 320.
Somatic mutations of PRR22:
Generating mutation plots.
Highly correlated genes for PRR22:
Showing top 20/24 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR22 | CEACAM3 | 0.67293 | 3 | 0 | 3 |
| PRR22 | C14orf39 | 0.646471 | 3 | 0 | 3 |
| PRR22 | EHMT2 | 0.617563 | 3 | 0 | 3 |
| PRR22 | HIVEP3 | 0.603166 | 4 | 0 | 3 |
| PRR22 | EPN1 | 0.597589 | 3 | 0 | 3 |
| PRR22 | B9D2 | 0.592277 | 3 | 0 | 3 |
| PRR22 | NOL4 | 0.576654 | 3 | 0 | 3 |
| PRR22 | CORO7 | 0.569423 | 3 | 0 | 3 |
| PRR22 | OR10C1 | 0.568743 | 3 | 0 | 3 |
| PRR22 | C15orf39 | 0.566022 | 4 | 0 | 3 |
| PRR22 | PRKD2 | 0.552264 | 4 | 0 | 3 |
| PRR22 | QTRT1 | 0.550341 | 4 | 0 | 3 |
| PRR22 | POLRMT | 0.549899 | 4 | 0 | 3 |
| PRR22 | HDHD3 | 0.547998 | 4 | 0 | 3 |
| PRR22 | ATG4D | 0.542493 | 4 | 0 | 3 |
| PRR22 | GSX2 | 0.540721 | 3 | 0 | 3 |
| PRR22 | ATAD3B | 0.530993 | 3 | 0 | 3 |
| PRR22 | AP1M2 | 0.52942 | 4 | 0 | 3 |
| PRR22 | CRIP2 | 0.526287 | 3 | 0 | 3 |
| PRR22 | PRKCZ | 0.523606 | 3 | 0 | 3 |
For details and further investigation, click here
