| Full name: haloacid dehalogenase like hydrolase domain containing 3 | Alias Symbol: MGC12904 | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 81932 | HGNC ID: HGNC:28171 | Ensembl Gene: ENSG00000119431 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HDHD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HDHD3 | 81932 | 221256_s_at | -0.4066 | 0.3818 | |
| GSE20347 | HDHD3 | 81932 | 221256_s_at | -0.7528 | 0.0000 | |
| GSE23400 | HDHD3 | 81932 | 221256_s_at | -0.3440 | 0.0001 | |
| GSE26886 | HDHD3 | 81932 | 221256_s_at | -0.4007 | 0.1934 | |
| GSE29001 | HDHD3 | 81932 | 221256_s_at | -0.5282 | 0.0103 | |
| GSE38129 | HDHD3 | 81932 | 221256_s_at | -0.4406 | 0.0159 | |
| GSE45670 | HDHD3 | 81932 | 221256_s_at | -0.0880 | 0.6713 | |
| GSE53622 | HDHD3 | 81932 | 31527 | -0.4237 | 0.0000 | |
| GSE53624 | HDHD3 | 81932 | 31527 | -0.6295 | 0.0000 | |
| GSE63941 | HDHD3 | 81932 | 221256_s_at | 2.0919 | 0.0002 | |
| GSE77861 | HDHD3 | 81932 | 221256_s_at | -0.0727 | 0.6877 | |
| GSE97050 | HDHD3 | 81932 | A_23_P112548 | -0.0447 | 0.8608 | |
| SRP007169 | HDHD3 | 81932 | RNAseq | -1.5307 | 0.0016 | |
| SRP008496 | HDHD3 | 81932 | RNAseq | -1.1672 | 0.0001 | |
| SRP064894 | HDHD3 | 81932 | RNAseq | -0.2823 | 0.4884 | |
| SRP133303 | HDHD3 | 81932 | RNAseq | -0.7277 | 0.0000 | |
| SRP159526 | HDHD3 | 81932 | RNAseq | -0.5589 | 0.0929 | |
| SRP193095 | HDHD3 | 81932 | RNAseq | -0.7781 | 0.0005 | |
| SRP219564 | HDHD3 | 81932 | RNAseq | -0.4569 | 0.4324 | |
| TCGA | HDHD3 | 81932 | RNAseq | -0.3256 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by HDHD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HDHD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HDHD3 | 81932 | 4 | 10 | 16 | |
| GSE20123 | HDHD3 | 81932 | 4 | 10 | 16 | |
| GSE43470 | HDHD3 | 81932 | 4 | 3 | 36 | |
| GSE46452 | HDHD3 | 81932 | 6 | 13 | 40 | |
| GSE47630 | HDHD3 | 81932 | 3 | 16 | 21 | |
| GSE54993 | HDHD3 | 81932 | 3 | 3 | 64 | |
| GSE54994 | HDHD3 | 81932 | 9 | 10 | 34 | |
| GSE60625 | HDHD3 | 81932 | 0 | 0 | 11 | |
| GSE74703 | HDHD3 | 81932 | 4 | 3 | 29 | |
| GSE74704 | HDHD3 | 81932 | 2 | 8 | 10 | |
| TCGA | HDHD3 | 81932 | 26 | 22 | 48 |
Total number of gains: 65; Total number of losses: 98; Total Number of normals: 325.
Somatic mutations of HDHD3:
Generating mutation plots.
Highly correlated genes for HDHD3:
Showing top 20/445 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HDHD3 | SDCBP2 | 0.705008 | 3 | 0 | 3 |
| HDHD3 | PRRG2 | 0.653153 | 9 | 0 | 9 |
| HDHD3 | HOOK2 | 0.641887 | 6 | 0 | 6 |
| HDHD3 | METTL18 | 0.640612 | 3 | 0 | 3 |
| HDHD3 | AP1G2 | 0.632271 | 4 | 0 | 4 |
| HDHD3 | EPN3 | 0.622193 | 10 | 0 | 9 |
| HDHD3 | RAB25 | 0.622049 | 12 | 0 | 10 |
| HDHD3 | GCHFR | 0.621526 | 8 | 0 | 7 |
| HDHD3 | SLC7A1 | 0.620555 | 4 | 0 | 3 |
| HDHD3 | FAM102A | 0.619881 | 11 | 0 | 8 |
| HDHD3 | EPS8L2 | 0.617337 | 9 | 0 | 7 |
| HDHD3 | EPHA1 | 0.617303 | 13 | 0 | 9 |
| HDHD3 | PTPN3 | 0.612885 | 11 | 0 | 8 |
| HDHD3 | TSTD1 | 0.612707 | 5 | 0 | 4 |
| HDHD3 | TJP3 | 0.61262 | 9 | 0 | 7 |
| HDHD3 | PTBP3 | 0.612269 | 5 | 0 | 4 |
| HDHD3 | PLA2G4F | 0.612038 | 4 | 0 | 3 |
| HDHD3 | SULT2B1 | 0.610525 | 8 | 0 | 6 |
| HDHD3 | A1CF | 0.609253 | 4 | 0 | 4 |
| HDHD3 | SH3GLB2 | 0.60901 | 10 | 0 | 8 |
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