| Full name: adhesion molecule with Ig like domain 2 | Alias Symbol: ALI1|DEGA | ||
| Type: protein-coding gene | Cytoband: 12q13.11 | ||
| Entrez ID: 347902 | HGNC ID: HGNC:24073 | Ensembl Gene: ENSG00000139211 | OMIM ID: 615690 |
| Drug and gene relationship at DGIdb | |||
Expression of AMIGO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMIGO2 | 347902 | 222108_at | 0.3743 | 0.6052 | |
| GSE20347 | AMIGO2 | 347902 | 222108_at | 1.4998 | 0.0018 | |
| GSE23400 | AMIGO2 | 347902 | 222108_at | 1.1191 | 0.0000 | |
| GSE26886 | AMIGO2 | 347902 | 222108_at | 2.3934 | 0.0005 | |
| GSE29001 | AMIGO2 | 347902 | 222108_at | 1.1090 | 0.0549 | |
| GSE38129 | AMIGO2 | 347902 | 222108_at | 1.1945 | 0.0027 | |
| GSE45670 | AMIGO2 | 347902 | 222108_at | -0.0597 | 0.9398 | |
| GSE53622 | AMIGO2 | 347902 | 78591 | 1.2649 | 0.0000 | |
| GSE53624 | AMIGO2 | 347902 | 78591 | 1.5292 | 0.0000 | |
| GSE63941 | AMIGO2 | 347902 | 222108_at | -0.2325 | 0.9139 | |
| GSE77861 | AMIGO2 | 347902 | 222108_at | 1.1988 | 0.1340 | |
| GSE97050 | AMIGO2 | 347902 | A_23_P14083 | 1.8368 | 0.0903 | |
| SRP007169 | AMIGO2 | 347902 | RNAseq | 3.4811 | 0.0000 | |
| SRP008496 | AMIGO2 | 347902 | RNAseq | 3.2576 | 0.0000 | |
| SRP064894 | AMIGO2 | 347902 | RNAseq | 1.4679 | 0.0000 | |
| SRP133303 | AMIGO2 | 347902 | RNAseq | 1.6718 | 0.0000 | |
| SRP159526 | AMIGO2 | 347902 | RNAseq | 0.2550 | 0.4564 | |
| SRP193095 | AMIGO2 | 347902 | RNAseq | 2.1370 | 0.0000 | |
| SRP219564 | AMIGO2 | 347902 | RNAseq | 1.1522 | 0.0036 | |
| TCGA | AMIGO2 | 347902 | RNAseq | 0.4563 | 0.0013 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by AMIGO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMIGO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMIGO2 | 347902 | 7 | 1 | 22 | |
| GSE20123 | AMIGO2 | 347902 | 7 | 1 | 22 | |
| GSE43470 | AMIGO2 | 347902 | 3 | 1 | 39 | |
| GSE46452 | AMIGO2 | 347902 | 8 | 1 | 50 | |
| GSE47630 | AMIGO2 | 347902 | 11 | 2 | 27 | |
| GSE54993 | AMIGO2 | 347902 | 0 | 5 | 65 | |
| GSE54994 | AMIGO2 | 347902 | 5 | 2 | 46 | |
| GSE60625 | AMIGO2 | 347902 | 0 | 0 | 11 | |
| GSE74703 | AMIGO2 | 347902 | 3 | 1 | 32 | |
| GSE74704 | AMIGO2 | 347902 | 3 | 1 | 16 | |
| TCGA | AMIGO2 | 347902 | 16 | 12 | 68 |
Total number of gains: 63; Total number of losses: 27; Total Number of normals: 398.
Somatic mutations of AMIGO2:
Generating mutation plots.
Highly correlated genes for AMIGO2:
Showing top 20/1247 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMIGO2 | LRRC8C | 0.779198 | 3 | 0 | 3 |
| AMIGO2 | STEAP1B | 0.769204 | 5 | 0 | 5 |
| AMIGO2 | B3GNT5 | 0.764205 | 3 | 0 | 3 |
| AMIGO2 | SPON2 | 0.757274 | 3 | 0 | 3 |
| AMIGO2 | DCBLD1 | 0.744129 | 7 | 0 | 6 |
| AMIGO2 | COL5A2 | 0.735037 | 11 | 0 | 11 |
| AMIGO2 | IL11 | 0.730715 | 4 | 0 | 4 |
| AMIGO2 | TGFBI | 0.723096 | 12 | 0 | 11 |
| AMIGO2 | PRSS23 | 0.718064 | 12 | 0 | 11 |
| AMIGO2 | RB1 | 0.717307 | 3 | 0 | 3 |
| AMIGO2 | FLRT2 | 0.714512 | 3 | 0 | 3 |
| AMIGO2 | RAPH1 | 0.71433 | 3 | 0 | 3 |
| AMIGO2 | INHBA | 0.713785 | 11 | 0 | 10 |
| AMIGO2 | FAP | 0.712974 | 9 | 0 | 9 |
| AMIGO2 | COL5A1 | 0.711337 | 11 | 0 | 11 |
| AMIGO2 | PDPN | 0.710724 | 9 | 0 | 9 |
| AMIGO2 | PTHLH | 0.708916 | 11 | 0 | 10 |
| AMIGO2 | SULF1 | 0.708609 | 9 | 0 | 9 |
| AMIGO2 | AHR | 0.708248 | 11 | 0 | 11 |
| AMIGO2 | APOC1 | 0.706525 | 4 | 0 | 4 |
For details and further investigation, click here
