| Full name: collagen type V alpha 2 chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q32.2 | ||
| Entrez ID: 1290 | HGNC ID: HGNC:2210 | Ensembl Gene: ENSG00000204262 | OMIM ID: 120190 |
| Drug and gene relationship at DGIdb | |||
Expression of COL5A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL5A2 | 1290 | 221729_at | 1.7690 | 0.0808 | |
| GSE20347 | COL5A2 | 1290 | 221729_at | 2.4586 | 0.0000 | |
| GSE23400 | COL5A2 | 1290 | 221729_at | 2.1888 | 0.0000 | |
| GSE26886 | COL5A2 | 1290 | 221729_at | 3.8032 | 0.0000 | |
| GSE29001 | COL5A2 | 1290 | 221729_at | 2.2221 | 0.0000 | |
| GSE38129 | COL5A2 | 1290 | 221729_at | 2.4137 | 0.0000 | |
| GSE45670 | COL5A2 | 1290 | 221729_at | 0.8157 | 0.2115 | |
| GSE53622 | COL5A2 | 1290 | 51731 | 2.9951 | 0.0000 | |
| GSE53624 | COL5A2 | 1290 | 51731 | 3.1470 | 0.0000 | |
| GSE63941 | COL5A2 | 1290 | 221729_at | -5.3114 | 0.0169 | |
| GSE77861 | COL5A2 | 1290 | 221729_at | 2.1865 | 0.0221 | |
| GSE97050 | COL5A2 | 1290 | A_23_P33196 | 1.8145 | 0.0631 | |
| SRP007169 | COL5A2 | 1290 | RNAseq | 6.4590 | 0.0000 | |
| SRP008496 | COL5A2 | 1290 | RNAseq | 6.3416 | 0.0000 | |
| SRP064894 | COL5A2 | 1290 | RNAseq | 2.9561 | 0.0000 | |
| SRP133303 | COL5A2 | 1290 | RNAseq | 3.2441 | 0.0000 | |
| SRP159526 | COL5A2 | 1290 | RNAseq | 1.4084 | 0.0000 | |
| SRP193095 | COL5A2 | 1290 | RNAseq | 3.8211 | 0.0000 | |
| SRP219564 | COL5A2 | 1290 | RNAseq | 1.9640 | 0.0003 | |
| TCGA | COL5A2 | 1290 | RNAseq | 0.4728 | 0.0000 |
Upregulated datasets: 15; Downregulated datasets: 1.
Survival by COL5A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL5A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL5A2 | 1290 | 9 | 2 | 19 | |
| GSE20123 | COL5A2 | 1290 | 9 | 2 | 19 | |
| GSE43470 | COL5A2 | 1290 | 3 | 1 | 39 | |
| GSE46452 | COL5A2 | 1290 | 1 | 4 | 54 | |
| GSE47630 | COL5A2 | 1290 | 4 | 5 | 31 | |
| GSE54993 | COL5A2 | 1290 | 0 | 5 | 65 | |
| GSE54994 | COL5A2 | 1290 | 12 | 6 | 35 | |
| GSE60625 | COL5A2 | 1290 | 0 | 3 | 8 | |
| GSE74703 | COL5A2 | 1290 | 2 | 1 | 33 | |
| GSE74704 | COL5A2 | 1290 | 3 | 2 | 15 | |
| TCGA | COL5A2 | 1290 | 23 | 7 | 66 |
Total number of gains: 66; Total number of losses: 38; Total Number of normals: 384.
Somatic mutations of COL5A2:
Generating mutation plots.
Highly correlated genes for COL5A2:
Showing top 20/1307 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL5A2 | COL5A1 | 0.901623 | 13 | 0 | 13 |
| COL5A2 | COL1A1 | 0.89789 | 12 | 0 | 12 |
| COL5A2 | COL3A1 | 0.895283 | 13 | 0 | 13 |
| COL5A2 | COL6A3 | 0.891114 | 13 | 0 | 13 |
| COL5A2 | COL1A2 | 0.888358 | 13 | 0 | 13 |
| COL5A2 | VCAN | 0.874247 | 13 | 0 | 13 |
| COL5A2 | SPARC | 0.870524 | 13 | 0 | 13 |
| COL5A2 | CTHRC1 | 0.867283 | 9 | 0 | 9 |
| COL5A2 | POSTN | 0.866567 | 13 | 0 | 13 |
| COL5A2 | FAP | 0.85175 | 11 | 0 | 11 |
| COL5A2 | BGN | 0.830236 | 13 | 0 | 13 |
| COL5A2 | MFAP2 | 0.828803 | 12 | 0 | 12 |
| COL5A2 | CDH11 | 0.828393 | 13 | 0 | 13 |
| COL5A2 | HTRA1 | 0.824635 | 13 | 0 | 13 |
| COL5A2 | INHBA | 0.823186 | 12 | 0 | 12 |
| COL5A2 | LOXL2 | 0.822226 | 12 | 0 | 12 |
| COL5A2 | THY1 | 0.814489 | 13 | 0 | 13 |
| COL5A2 | CTSK | 0.808584 | 13 | 0 | 13 |
| COL5A2 | TGFBI | 0.803399 | 13 | 0 | 12 |
| COL5A2 | ZNF469 | 0.800897 | 8 | 0 | 8 |
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