| Full name: lactate dehydrogenase A like 6B | Alias Symbol: LDHL|LDH6B | ||
| Type: protein-coding gene | Cytoband: 15q22.2 | ||
| Entrez ID: 92483 | HGNC ID: HGNC:21481 | Ensembl Gene: ENSG00000171989 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LDHAL6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LDHAL6B | 92483 | 210712_at | 0.1455 | 0.5034 | |
| GSE20347 | LDHAL6B | 92483 | 210712_at | 0.0856 | 0.1301 | |
| GSE23400 | LDHAL6B | 92483 | 210712_at | 0.0012 | 0.9738 | |
| GSE26886 | LDHAL6B | 92483 | 210712_at | -0.0380 | 0.6940 | |
| GSE29001 | LDHAL6B | 92483 | 210712_at | -0.0046 | 0.9782 | |
| GSE38129 | LDHAL6B | 92483 | 210712_at | 0.0176 | 0.7509 | |
| GSE45670 | LDHAL6B | 92483 | 210712_at | 0.1805 | 0.0417 | |
| GSE53622 | LDHAL6B | 92483 | 9161 | 0.0838 | 0.4050 | |
| GSE53624 | LDHAL6B | 92483 | 9161 | -0.1690 | 0.0805 | |
| GSE63941 | LDHAL6B | 92483 | 210712_at | 0.2163 | 0.0358 | |
| GSE77861 | LDHAL6B | 92483 | 210712_at | 0.0313 | 0.7871 | |
| SRP133303 | LDHAL6B | 92483 | RNAseq | 0.5612 | 0.0100 | |
| SRP193095 | LDHAL6B | 92483 | RNAseq | -0.1363 | 0.5374 | |
| TCGA | LDHAL6B | 92483 | RNAseq | 0.1228 | 0.6949 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LDHAL6B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LDHAL6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LDHAL6B | 92483 | 6 | 4 | 20 | |
| GSE20123 | LDHAL6B | 92483 | 6 | 3 | 21 | |
| GSE43470 | LDHAL6B | 92483 | 4 | 4 | 35 | |
| GSE46452 | LDHAL6B | 92483 | 3 | 7 | 49 | |
| GSE47630 | LDHAL6B | 92483 | 8 | 10 | 22 | |
| GSE54993 | LDHAL6B | 92483 | 5 | 6 | 59 | |
| GSE54994 | LDHAL6B | 92483 | 6 | 8 | 39 | |
| GSE60625 | LDHAL6B | 92483 | 4 | 0 | 7 | |
| GSE74703 | LDHAL6B | 92483 | 4 | 3 | 29 | |
| GSE74704 | LDHAL6B | 92483 | 2 | 3 | 15 | |
| TCGA | LDHAL6B | 92483 | 10 | 16 | 70 |
Total number of gains: 58; Total number of losses: 64; Total Number of normals: 366.
Somatic mutations of LDHAL6B:
Generating mutation plots.
Highly correlated genes for LDHAL6B:
Showing top 20/161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LDHAL6B | SIPA1 | 0.664586 | 3 | 0 | 3 |
| LDHAL6B | KIR2DL5A | 0.627113 | 5 | 0 | 5 |
| LDHAL6B | KCNJ13 | 0.62042 | 3 | 0 | 3 |
| LDHAL6B | TNR | 0.618719 | 4 | 0 | 4 |
| LDHAL6B | PSG3 | 0.614909 | 5 | 0 | 4 |
| LDHAL6B | DNAJA4 | 0.614776 | 4 | 0 | 3 |
| LDHAL6B | CCDC30 | 0.614189 | 3 | 0 | 3 |
| LDHAL6B | TM4SF4 | 0.61402 | 4 | 0 | 4 |
| LDHAL6B | CD4 | 0.612332 | 4 | 0 | 3 |
| LDHAL6B | OR1F1 | 0.611419 | 3 | 0 | 3 |
| LDHAL6B | NEUROD2 | 0.608611 | 4 | 0 | 4 |
| LDHAL6B | TRPM6 | 0.607059 | 6 | 0 | 5 |
| LDHAL6B | ACSBG2 | 0.604271 | 5 | 0 | 3 |
| LDHAL6B | KIF21B | 0.601463 | 5 | 0 | 3 |
| LDHAL6B | KIR3DL3 | 0.60143 | 6 | 0 | 4 |
| LDHAL6B | GPA33 | 0.599509 | 5 | 0 | 4 |
| LDHAL6B | TRPM3 | 0.595347 | 5 | 0 | 3 |
| LDHAL6B | PVR | 0.594822 | 3 | 0 | 3 |
| LDHAL6B | CYP2A7 | 0.593543 | 5 | 0 | 4 |
| LDHAL6B | IRS4 | 0.592107 | 4 | 0 | 3 |
For details and further investigation, click here
