| Full name: PSMC3 interacting protein | Alias Symbol: TBPIP|GT198|HUMGT198A|Hop2 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 29893 | HGNC ID: HGNC:17928 | Ensembl Gene: ENSG00000131470 | OMIM ID: 608665 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PSMC3IP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMC3IP | 29893 | 205956_x_at | 0.3674 | 0.1421 | |
| GSE20347 | PSMC3IP | 29893 | 205956_x_at | 0.3265 | 0.0002 | |
| GSE23400 | PSMC3IP | 29893 | 205956_x_at | 0.2176 | 0.0000 | |
| GSE26886 | PSMC3IP | 29893 | 205956_x_at | 0.2131 | 0.0581 | |
| GSE29001 | PSMC3IP | 29893 | 205956_x_at | 0.4563 | 0.0052 | |
| GSE38129 | PSMC3IP | 29893 | 205956_x_at | 0.3985 | 0.0000 | |
| GSE45670 | PSMC3IP | 29893 | 205956_x_at | 0.5854 | 0.0000 | |
| GSE53622 | PSMC3IP | 29893 | 45107 | 0.9579 | 0.0000 | |
| GSE53624 | PSMC3IP | 29893 | 45107 | 0.9191 | 0.0000 | |
| GSE63941 | PSMC3IP | 29893 | 205956_x_at | 0.3916 | 0.1823 | |
| GSE77861 | PSMC3IP | 29893 | 205956_x_at | 0.3703 | 0.0032 | |
| GSE97050 | PSMC3IP | 29893 | A_24_P287941 | 0.1759 | 0.6388 | |
| SRP007169 | PSMC3IP | 29893 | RNAseq | 3.8262 | 0.0015 | |
| SRP064894 | PSMC3IP | 29893 | RNAseq | 1.6461 | 0.0000 | |
| SRP133303 | PSMC3IP | 29893 | RNAseq | 1.2112 | 0.0000 | |
| SRP159526 | PSMC3IP | 29893 | RNAseq | 1.9236 | 0.0000 | |
| SRP193095 | PSMC3IP | 29893 | RNAseq | 0.8342 | 0.0000 | |
| SRP219564 | PSMC3IP | 29893 | RNAseq | 1.0321 | 0.0121 | |
| TCGA | PSMC3IP | 29893 | RNAseq | 0.6372 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by PSMC3IP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMC3IP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMC3IP | 29893 | 6 | 2 | 22 | |
| GSE20123 | PSMC3IP | 29893 | 6 | 2 | 22 | |
| GSE43470 | PSMC3IP | 29893 | 1 | 2 | 40 | |
| GSE46452 | PSMC3IP | 29893 | 34 | 0 | 25 | |
| GSE47630 | PSMC3IP | 29893 | 8 | 1 | 31 | |
| GSE54993 | PSMC3IP | 29893 | 3 | 4 | 63 | |
| GSE54994 | PSMC3IP | 29893 | 8 | 5 | 40 | |
| GSE60625 | PSMC3IP | 29893 | 4 | 0 | 7 | |
| GSE74703 | PSMC3IP | 29893 | 1 | 1 | 34 | |
| GSE74704 | PSMC3IP | 29893 | 4 | 1 | 15 | |
| TCGA | PSMC3IP | 29893 | 23 | 6 | 67 |
Total number of gains: 98; Total number of losses: 24; Total Number of normals: 366.
Somatic mutations of PSMC3IP:
Generating mutation plots.
Highly correlated genes for PSMC3IP:
Showing top 20/1786 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMC3IP | TAB1 | 0.762816 | 3 | 0 | 3 |
| PSMC3IP | ZNF598 | 0.751752 | 3 | 0 | 3 |
| PSMC3IP | ISY1 | 0.747404 | 3 | 0 | 3 |
| PSMC3IP | SLC15A4 | 0.729641 | 3 | 0 | 3 |
| PSMC3IP | DNTTIP1 | 0.728227 | 6 | 0 | 6 |
| PSMC3IP | TTL | 0.722947 | 6 | 0 | 6 |
| PSMC3IP | EIF5B | 0.722408 | 3 | 0 | 3 |
| PSMC3IP | SLC7A6OS | 0.721181 | 4 | 0 | 4 |
| PSMC3IP | PYCR2 | 0.720344 | 3 | 0 | 3 |
| PSMC3IP | RAB34 | 0.719506 | 3 | 0 | 3 |
| PSMC3IP | SCNM1 | 0.715348 | 3 | 0 | 3 |
| PSMC3IP | SLC44A1 | 0.713977 | 5 | 0 | 5 |
| PSMC3IP | IFT172 | 0.713815 | 3 | 0 | 3 |
| PSMC3IP | MMS22L | 0.710218 | 3 | 0 | 3 |
| PSMC3IP | EBNA1BP2 | 0.708858 | 3 | 0 | 3 |
| PSMC3IP | GGNBP2 | 0.705766 | 3 | 0 | 3 |
| PSMC3IP | DHX33 | 0.705601 | 6 | 0 | 6 |
| PSMC3IP | RFTN2 | 0.703441 | 3 | 0 | 3 |
| PSMC3IP | MRPL47 | 0.702221 | 6 | 0 | 6 |
| PSMC3IP | CATSPER1 | 0.700751 | 4 | 0 | 4 |
For details and further investigation, click here
