| Full name: solute carrier family 44 member 1 | Alias Symbol: CDw92|CTL1|CHTL1|CD92 | ||
| Type: protein-coding gene | Cytoband: 9q31.1-q31.2 | ||
| Entrez ID: 23446 | HGNC ID: HGNC:18798 | Ensembl Gene: ENSG00000070214 | OMIM ID: 606105 |
| Drug and gene relationship at DGIdb | |||
SLC44A1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05231 | Choline metabolism in cancer |
Expression of SLC44A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC44A1 | 23446 | 224596_at | 0.4556 | 0.5789 | |
| GSE20347 | SLC44A1 | 23446 | 222364_at | 0.0563 | 0.7921 | |
| GSE23400 | SLC44A1 | 23446 | 222364_at | 0.0327 | 0.3566 | |
| GSE26886 | SLC44A1 | 23446 | 224596_at | 1.1573 | 0.0000 | |
| GSE29001 | SLC44A1 | 23446 | 222364_at | 0.0476 | 0.8899 | |
| GSE38129 | SLC44A1 | 23446 | 222364_at | -0.0403 | 0.8470 | |
| GSE45670 | SLC44A1 | 23446 | 224596_at | 0.8655 | 0.0000 | |
| GSE53622 | SLC44A1 | 23446 | 74042 | 0.7485 | 0.0000 | |
| GSE53624 | SLC44A1 | 23446 | 74042 | 0.9732 | 0.0000 | |
| GSE63941 | SLC44A1 | 23446 | 224596_at | 0.0875 | 0.8594 | |
| GSE77861 | SLC44A1 | 23446 | 224596_at | 1.0421 | 0.0032 | |
| GSE97050 | SLC44A1 | 23446 | A_23_P216630 | 0.5177 | 0.1581 | |
| SRP007169 | SLC44A1 | 23446 | RNAseq | 1.5098 | 0.0002 | |
| SRP008496 | SLC44A1 | 23446 | RNAseq | 1.2665 | 0.0000 | |
| SRP064894 | SLC44A1 | 23446 | RNAseq | 0.9289 | 0.0000 | |
| SRP133303 | SLC44A1 | 23446 | RNAseq | 0.8856 | 0.0001 | |
| SRP159526 | SLC44A1 | 23446 | RNAseq | 0.8791 | 0.0124 | |
| SRP193095 | SLC44A1 | 23446 | RNAseq | 0.1358 | 0.4570 | |
| SRP219564 | SLC44A1 | 23446 | RNAseq | 0.3219 | 0.3580 | |
| TCGA | SLC44A1 | 23446 | RNAseq | 0.1511 | 0.0085 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by SLC44A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC44A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC44A1 | 23446 | 4 | 10 | 16 | |
| GSE20123 | SLC44A1 | 23446 | 5 | 9 | 16 | |
| GSE43470 | SLC44A1 | 23446 | 7 | 3 | 33 | |
| GSE46452 | SLC44A1 | 23446 | 6 | 13 | 40 | |
| GSE47630 | SLC44A1 | 23446 | 1 | 17 | 22 | |
| GSE54993 | SLC44A1 | 23446 | 3 | 3 | 64 | |
| GSE54994 | SLC44A1 | 23446 | 9 | 10 | 34 | |
| GSE60625 | SLC44A1 | 23446 | 0 | 0 | 11 | |
| GSE74703 | SLC44A1 | 23446 | 6 | 3 | 27 | |
| GSE74704 | SLC44A1 | 23446 | 2 | 6 | 12 | |
| TCGA | SLC44A1 | 23446 | 26 | 21 | 49 |
Total number of gains: 69; Total number of losses: 95; Total Number of normals: 324.
Somatic mutations of SLC44A1:
Generating mutation plots.
Highly correlated genes for SLC44A1:
Showing top 20/1494 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC44A1 | U2SURP | 0.803824 | 4 | 0 | 4 |
| SLC44A1 | TAS2R19 | 0.797251 | 3 | 0 | 3 |
| SLC44A1 | PLEKHA3 | 0.7951 | 3 | 0 | 3 |
| SLC44A1 | THAP5 | 0.762485 | 3 | 0 | 3 |
| SLC44A1 | SFR1 | 0.760982 | 3 | 0 | 3 |
| SLC44A1 | EFTUD2 | 0.756312 | 6 | 0 | 6 |
| SLC44A1 | DNAJB11 | 0.746252 | 5 | 0 | 5 |
| SLC44A1 | MORC2 | 0.746111 | 6 | 0 | 5 |
| SLC44A1 | ZBED1 | 0.745838 | 3 | 0 | 3 |
| SLC44A1 | PLXNA1 | 0.745712 | 7 | 0 | 7 |
| SLC44A1 | ZNF417 | 0.744726 | 3 | 0 | 3 |
| SLC44A1 | CPSF6 | 0.742674 | 6 | 0 | 6 |
| SLC44A1 | CMSS1 | 0.741741 | 5 | 0 | 5 |
| SLC44A1 | PRPF4 | 0.740828 | 8 | 0 | 8 |
| SLC44A1 | MRPL4 | 0.738231 | 4 | 0 | 4 |
| SLC44A1 | MRPL47 | 0.737137 | 8 | 0 | 7 |
| SLC44A1 | SET | 0.736286 | 5 | 0 | 5 |
| SLC44A1 | RPL39L | 0.735046 | 7 | 0 | 7 |
| SLC44A1 | PYCR2 | 0.734341 | 3 | 0 | 3 |
| SLC44A1 | EFNA1 | 0.732887 | 6 | 0 | 6 |
For details and further investigation, click here
