HMMR

 

Full name: hyaluronan mediated motility receptor Alias Symbol: RHAMM|CD168
Type: protein-coding gene Cytoband: 5q34
Entrez ID: 3161 HGNC ID: HGNC:5012 Ensembl Gene: ENSG00000072571 OMIM ID: 600936
Drug and gene relationship at DGIdb

 

Expression of HMMR:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HMMR 3161 207165_at 1.5139 0.0738
GSE20347 HMMR 3161 207165_at 1.6409 0.0000
GSE23400 HMMR 3161 207165_at 1.0980 0.0000
GSE26886 HMMR 3161 207165_at 0.8460 0.0569
GSE29001 HMMR 3161 207165_at 1.6285 0.0008
GSE38129 HMMR 3161 207165_at 2.0000 0.0000
GSE45670 HMMR 3161 207165_at 1.6232 0.0000
GSE53622 HMMR 3161 19626 1.4418 0.0000
GSE53624 HMMR 3161 19626 1.7499 0.0000
GSE63941 HMMR 3161 207165_at 3.3868 0.0006
GSE77861 HMMR 3161 207165_at 1.2033 0.0270
GSE97050 HMMR 3161 A_23_P70007 0.7991 0.1822
SRP007169 HMMR 3161 RNAseq 0.8742 0.0800
SRP008496 HMMR 3161 RNAseq 1.0308 0.0080
SRP064894 HMMR 3161 RNAseq 1.6507 0.0000
SRP133303 HMMR 3161 RNAseq 1.9299 0.0000
SRP159526 HMMR 3161 RNAseq 0.4749 0.2770
SRP193095 HMMR 3161 RNAseq 0.6291 0.0007
SRP219564 HMMR 3161 RNAseq 1.0467 0.1873
TCGA HMMR 3161 RNAseq 1.1720 0.0000

Upregulated datasets: 13; Downregulated datasets: 0.  

 

Survival by HMMR expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of HMMR:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HMMR 3161 0 12 18
GSE20123 HMMR 3161 0 12 18
GSE43470 HMMR 3161 2 10 31
GSE46452 HMMR 3161 0 27 32
GSE47630 HMMR 3161 0 20 20
GSE54993 HMMR 3161 9 2 59
GSE54994 HMMR 3161 2 15 36
GSE60625 HMMR 3161 1 0 10
GSE74703 HMMR 3161 2 8 26
GSE74704 HMMR 3161 0 7 13
TCGA HMMR 3161 6 38 52

Total number of gains: 22; Total number of losses: 151; Total Number of normals: 315.  

 

Somatic mutations of HMMR:

 

Generating mutation plots.

 

Highly correlated genes for HMMR:

 

Showing top 20/1949 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HMMRBUB1B0.842816909
HMMRKIF140.83161212012
HMMRKIF20A0.82620513013
HMMRAURKB0.82435912012
HMMRCDC200.82043412011
HMMRCEP550.81950413013
HMMRCDK10.81081712011
HMMRTPX20.80912913012
HMMRASPM0.80840413012
HMMRPBK0.80643313012
HMMRNEK20.80554213012
HMMRTTK0.80199613013
HMMRBUB10.80184211010
HMMRSHCBP10.80143612012
HMMRDLGAP50.80054813012
HMMRCCNB20.80019213013
HMMRDEPDC10.79795113013
HMMRNCAPH0.796776909
HMMRCDKN30.79663313012
HMMRSPDL10.79594210010

For details and further investigation, click here