| Full name: phosphoseryl-tRNA kinase | Alias Symbol: MGC35392 | ||
| Type: protein-coding gene | Cytoband: 10q26.13 | ||
| Entrez ID: 118672 | HGNC ID: HGNC:28578 | Ensembl Gene: ENSG00000179988 | OMIM ID: 611310 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PSTK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSTK | 118672 | 230129_at | 0.1666 | 0.9028 | |
| GSE26886 | PSTK | 118672 | 230129_at | 0.3431 | 0.2157 | |
| GSE45670 | PSTK | 118672 | 230129_at | -0.0893 | 0.6862 | |
| GSE53622 | PSTK | 118672 | 73464 | -0.1301 | 0.1648 | |
| GSE53624 | PSTK | 118672 | 73464 | -0.0421 | 0.6503 | |
| GSE63941 | PSTK | 118672 | 230129_at | -0.0771 | 0.8730 | |
| GSE77861 | PSTK | 118672 | 240040_at | -0.1738 | 0.1212 | |
| GSE97050 | PSTK | 118672 | A_23_P12866 | 0.2224 | 0.3981 | |
| SRP064894 | PSTK | 118672 | RNAseq | 0.0297 | 0.9024 | |
| SRP133303 | PSTK | 118672 | RNAseq | -0.1712 | 0.3518 | |
| SRP159526 | PSTK | 118672 | RNAseq | -0.1018 | 0.7385 | |
| SRP193095 | PSTK | 118672 | RNAseq | -0.3309 | 0.0418 | |
| SRP219564 | PSTK | 118672 | RNAseq | 0.0401 | 0.9022 | |
| TCGA | PSTK | 118672 | RNAseq | -0.0817 | 0.5098 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSTK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSTK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSTK | 118672 | 1 | 6 | 23 | |
| GSE20123 | PSTK | 118672 | 1 | 6 | 23 | |
| GSE43470 | PSTK | 118672 | 0 | 9 | 34 | |
| GSE46452 | PSTK | 118672 | 0 | 11 | 48 | |
| GSE47630 | PSTK | 118672 | 2 | 14 | 24 | |
| GSE54993 | PSTK | 118672 | 8 | 1 | 61 | |
| GSE54994 | PSTK | 118672 | 1 | 9 | 43 | |
| GSE60625 | PSTK | 118672 | 0 | 0 | 11 | |
| GSE74703 | PSTK | 118672 | 0 | 6 | 30 | |
| GSE74704 | PSTK | 118672 | 1 | 2 | 17 | |
| TCGA | PSTK | 118672 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 92; Total Number of normals: 378.
Somatic mutations of PSTK:
Generating mutation plots.
Highly correlated genes for PSTK:
Showing top 20/30 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSTK | ZNF296 | 0.6627 | 3 | 0 | 3 |
| PSTK | USP27X | 0.661781 | 3 | 0 | 3 |
| PSTK | CELSR3 | 0.639966 | 4 | 0 | 3 |
| PSTK | PRPF31 | 0.633948 | 3 | 0 | 3 |
| PSTK | TRIM31 | 0.630089 | 3 | 0 | 3 |
| PSTK | SLC45A3 | 0.622661 | 3 | 0 | 3 |
| PSTK | CPO | 0.617555 | 3 | 0 | 3 |
| PSTK | ZNF777 | 0.601577 | 3 | 0 | 3 |
| PSTK | TSNAXIP1 | 0.594149 | 4 | 0 | 3 |
| PSTK | PHKA2 | 0.589869 | 4 | 0 | 3 |
| PSTK | IL10RA | 0.580261 | 4 | 0 | 3 |
| PSTK | GPC2 | 0.57351 | 3 | 0 | 3 |
| PSTK | PUS3 | 0.570903 | 3 | 0 | 3 |
| PSTK | ZNF230 | 0.565021 | 4 | 0 | 3 |
| PSTK | GPAM | 0.559101 | 5 | 0 | 3 |
| PSTK | MACROD1 | 0.552223 | 5 | 0 | 3 |
| PSTK | LYPLA2 | 0.550105 | 4 | 0 | 3 |
| PSTK | RAD18 | 0.547441 | 5 | 0 | 3 |
| PSTK | YEATS4 | 0.541002 | 5 | 0 | 4 |
| PSTK | AGAP3 | 0.537901 | 4 | 0 | 3 |
For details and further investigation, click here
