| Full name: carboxypeptidase O | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q33.3 | ||
| Entrez ID: 130749 | HGNC ID: HGNC:21011 | Ensembl Gene: ENSG00000144410 | OMIM ID: 609563 |
| Drug and gene relationship at DGIdb | |||
Expression of CPO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPO | 130749 | 1553506_at | -0.1315 | 0.7208 | |
| GSE26886 | CPO | 130749 | 1553506_at | -0.0281 | 0.7715 | |
| GSE45670 | CPO | 130749 | 1553506_at | -0.0531 | 0.6150 | |
| GSE53622 | CPO | 130749 | 19303 | -0.9486 | 0.0000 | |
| GSE53624 | CPO | 130749 | 19303 | -1.1975 | 0.0000 | |
| GSE63941 | CPO | 130749 | 1553506_at | -0.0571 | 0.6877 | |
| GSE77861 | CPO | 130749 | 1553506_at | -0.1719 | 0.0815 | |
| TCGA | CPO | 130749 | RNAseq | -2.5382 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CPO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPO | 130749 | 3 | 6 | 21 | |
| GSE20123 | CPO | 130749 | 3 | 6 | 21 | |
| GSE43470 | CPO | 130749 | 2 | 4 | 37 | |
| GSE46452 | CPO | 130749 | 1 | 4 | 54 | |
| GSE47630 | CPO | 130749 | 4 | 5 | 31 | |
| GSE54993 | CPO | 130749 | 0 | 3 | 67 | |
| GSE54994 | CPO | 130749 | 8 | 9 | 36 | |
| GSE60625 | CPO | 130749 | 0 | 3 | 8 | |
| GSE74703 | CPO | 130749 | 2 | 3 | 31 | |
| GSE74704 | CPO | 130749 | 2 | 2 | 16 | |
| TCGA | CPO | 130749 | 14 | 22 | 60 |
Total number of gains: 39; Total number of losses: 67; Total Number of normals: 382.
Somatic mutations of CPO:
Generating mutation plots.
Highly correlated genes for CPO:
Showing top 20/80 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPO | KIAA0232 | 0.625606 | 4 | 0 | 3 |
| CPO | RPL34 | 0.619308 | 3 | 0 | 3 |
| CPO | PSTK | 0.617555 | 3 | 0 | 3 |
| CPO | CIPC | 0.614705 | 4 | 0 | 3 |
| CPO | SAP18 | 0.614231 | 3 | 0 | 3 |
| CPO | MYL9 | 0.601994 | 3 | 0 | 3 |
| CPO | RGN | 0.597087 | 3 | 0 | 3 |
| CPO | STK39 | 0.591235 | 4 | 0 | 4 |
| CPO | SUCLG2 | 0.590783 | 4 | 0 | 4 |
| CPO | TCAIM | 0.589003 | 3 | 0 | 3 |
| CPO | SLC6A16 | 0.588902 | 3 | 0 | 3 |
| CPO | LINC01354 | 0.585656 | 3 | 0 | 3 |
| CPO | CLYBL | 0.584333 | 4 | 0 | 3 |
| CPO | OXR1 | 0.584247 | 4 | 0 | 3 |
| CPO | PDZRN4 | 0.582085 | 4 | 0 | 3 |
| CPO | TADA2B | 0.58119 | 3 | 0 | 3 |
| CPO | SORBS2 | 0.580252 | 3 | 0 | 3 |
| CPO | ACADM | 0.578285 | 3 | 0 | 3 |
| CPO | BHMT2 | 0.577226 | 3 | 0 | 3 |
| CPO | NFIA | 0.576367 | 4 | 0 | 3 |
For details and further investigation, click here
