PSTPIP2

 

Full name: proline-serine-threonine phosphatase interacting protein 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 18q21.1
Entrez ID: 9050 HGNC ID: HGNC:9581 Ensembl Gene: ENSG00000152229 OMIM ID: 616046
Drug and gene relationship at DGIdb

 

Expression of PSTPIP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PSTPIP2 9050 219938_s_at 0.9391 0.2084
GSE20347 PSTPIP2 9050 219938_s_at 0.2540 0.3092
GSE23400 PSTPIP2 9050 219938_s_at 0.1880 0.0052
GSE26886 PSTPIP2 9050 219938_s_at 0.2509 0.6783
GSE29001 PSTPIP2 9050 219938_s_at 0.1762 0.6143
GSE38129 PSTPIP2 9050 219938_s_at 0.4944 0.0121
GSE45670 PSTPIP2 9050 219938_s_at 0.6040 0.0851
GSE53622 PSTPIP2 9050 70001 0.9619 0.0000
GSE53624 PSTPIP2 9050 70001 0.7533 0.0000
GSE63941 PSTPIP2 9050 219938_s_at 0.5053 0.5607
GSE77861 PSTPIP2 9050 219938_s_at 0.2669 0.4164
GSE97050 PSTPIP2 9050 A_24_P322353 0.5367 0.2307
SRP007169 PSTPIP2 9050 RNAseq 1.2538 0.0326
SRP008496 PSTPIP2 9050 RNAseq 2.1222 0.0050
SRP064894 PSTPIP2 9050 RNAseq -0.1286 0.5985
SRP133303 PSTPIP2 9050 RNAseq 0.6024 0.0053
SRP159526 PSTPIP2 9050 RNAseq 0.5182 0.0324
SRP193095 PSTPIP2 9050 RNAseq 0.6325 0.0028
SRP219564 PSTPIP2 9050 RNAseq 0.1912 0.6627
TCGA PSTPIP2 9050 RNAseq 0.1767 0.1175

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by PSTPIP2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PSTPIP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PSTPIP2 9050 1 8 21
GSE20123 PSTPIP2 9050 1 8 21
GSE43470 PSTPIP2 9050 0 4 39
GSE46452 PSTPIP2 9050 1 26 32
GSE47630 PSTPIP2 9050 5 20 15
GSE54993 PSTPIP2 9050 8 1 61
GSE54994 PSTPIP2 9050 2 15 36
GSE60625 PSTPIP2 9050 0 4 7
GSE74703 PSTPIP2 9050 0 3 33
GSE74704 PSTPIP2 9050 0 6 14
TCGA PSTPIP2 9050 15 40 41

Total number of gains: 33; Total number of losses: 135; Total Number of normals: 320.  


 

Somatic mutations of PSTPIP2:

 

Generating mutation plots.

 

Highly correlated genes for PSTPIP2:

 

Showing top 20/583 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PSTPIP2PREX10.819884303
PSTPIP2CISD20.779305303
PSTPIP2INTS100.777911303
PSTPIP2MS4A140.73335303
PSTPIP2HELB0.73036303
PSTPIP2MAN1A20.726217303
PSTPIP2DDX60L0.718164303
PSTPIP2DGKD0.714801303
PSTPIP2C1orf1150.714119303
PSTPIP2CCT6A0.711921303
PSTPIP2METTL170.705217303
PSTPIP2MAZ0.699168303
PSTPIP2CDCA70.697528403
PSTPIP2TRAF50.696347303
PSTPIP2NAB20.695388303
PSTPIP2CELSR20.692514303
PSTPIP2HORMAD10.688591303
PSTPIP2RNF1450.685588303
PSTPIP2FNTA0.684851303
PSTPIP2LRP40.684102303

For details and further investigation, click here