| Full name: NGFI-A binding protein 2 | Alias Symbol: MADER | ||
| Type: protein-coding gene | Cytoband: 12q13.3 | ||
| Entrez ID: 4665 | HGNC ID: HGNC:7627 | Ensembl Gene: ENSG00000166886 | OMIM ID: 602381 |
| Drug and gene relationship at DGIdb | |||
Expression of NAB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAB2 | 4665 | 212803_at | 0.3009 | 0.3997 | |
| GSE20347 | NAB2 | 4665 | 212803_at | 0.3803 | 0.0008 | |
| GSE23400 | NAB2 | 4665 | 212803_at | 0.2661 | 0.0006 | |
| GSE26886 | NAB2 | 4665 | 212803_at | 0.5088 | 0.0030 | |
| GSE29001 | NAB2 | 4665 | 212803_at | 0.2533 | 0.4192 | |
| GSE38129 | NAB2 | 4665 | 212803_at | 0.3374 | 0.0011 | |
| GSE45670 | NAB2 | 4665 | 212803_at | 0.1682 | 0.3269 | |
| GSE53622 | NAB2 | 4665 | 155927 | 0.4214 | 0.0016 | |
| GSE53624 | NAB2 | 4665 | 155927 | 0.7614 | 0.0000 | |
| GSE63941 | NAB2 | 4665 | 212803_at | -0.1842 | 0.7172 | |
| GSE77861 | NAB2 | 4665 | 212803_at | 0.4011 | 0.0695 | |
| GSE97050 | NAB2 | 4665 | A_33_P3248794 | -0.1215 | 0.5742 | |
| SRP007169 | NAB2 | 4665 | RNAseq | 1.4882 | 0.0021 | |
| SRP008496 | NAB2 | 4665 | RNAseq | 2.0624 | 0.0000 | |
| SRP064894 | NAB2 | 4665 | RNAseq | 0.2973 | 0.1840 | |
| SRP133303 | NAB2 | 4665 | RNAseq | 0.3801 | 0.0593 | |
| SRP159526 | NAB2 | 4665 | RNAseq | 0.7842 | 0.0383 | |
| SRP193095 | NAB2 | 4665 | RNAseq | 0.6592 | 0.0003 | |
| SRP219564 | NAB2 | 4665 | RNAseq | -0.2745 | 0.2758 | |
| TCGA | NAB2 | 4665 | RNAseq | 0.2362 | 0.0002 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NAB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAB2 | 4665 | 7 | 1 | 22 | |
| GSE20123 | NAB2 | 4665 | 7 | 0 | 23 | |
| GSE43470 | NAB2 | 4665 | 3 | 0 | 40 | |
| GSE46452 | NAB2 | 4665 | 8 | 1 | 50 | |
| GSE47630 | NAB2 | 4665 | 10 | 2 | 28 | |
| GSE54993 | NAB2 | 4665 | 0 | 5 | 65 | |
| GSE54994 | NAB2 | 4665 | 4 | 1 | 48 | |
| GSE60625 | NAB2 | 4665 | 0 | 0 | 11 | |
| GSE74703 | NAB2 | 4665 | 3 | 0 | 33 | |
| GSE74704 | NAB2 | 4665 | 4 | 0 | 16 | |
| TCGA | NAB2 | 4665 | 14 | 10 | 72 |
Total number of gains: 60; Total number of losses: 20; Total Number of normals: 408.
Somatic mutations of NAB2:
Generating mutation plots.
Highly correlated genes for NAB2:
Showing top 20/695 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAB2 | GNS | 0.744791 | 3 | 0 | 3 |
| NAB2 | TAF1C | 0.740814 | 4 | 0 | 3 |
| NAB2 | KDM5A | 0.738745 | 3 | 0 | 3 |
| NAB2 | KIAA1257 | 0.721297 | 3 | 0 | 3 |
| NAB2 | GTPBP6 | 0.715428 | 3 | 0 | 3 |
| NAB2 | NBAS | 0.714481 | 3 | 0 | 3 |
| NAB2 | HES6 | 0.711648 | 3 | 0 | 3 |
| NAB2 | MLLT1 | 0.709939 | 4 | 0 | 3 |
| NAB2 | QTRT1 | 0.708967 | 4 | 0 | 4 |
| NAB2 | MRPL38 | 0.707602 | 3 | 0 | 3 |
| NAB2 | ZHX2 | 0.706636 | 4 | 0 | 4 |
| NAB2 | COPS7A | 0.70567 | 3 | 0 | 3 |
| NAB2 | PSTPIP2 | 0.695388 | 3 | 0 | 3 |
| NAB2 | MAP4K4 | 0.694881 | 3 | 0 | 3 |
| NAB2 | DIP2B | 0.694637 | 3 | 0 | 3 |
| NAB2 | DERL3 | 0.69437 | 3 | 0 | 3 |
| NAB2 | BCL9 | 0.691239 | 3 | 0 | 3 |
| NAB2 | ICAM1 | 0.68806 | 3 | 0 | 3 |
| NAB2 | GAS2L1 | 0.685866 | 3 | 0 | 3 |
| NAB2 | C7orf50 | 0.685586 | 3 | 0 | 3 |
For details and further investigation, click here
