| Full name: phosphatidylserine synthase 2 | Alias Symbol: PSS2 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 81490 | HGNC ID: HGNC:15463 | Ensembl Gene: ENSG00000174915 | OMIM ID: 612793 |
| Drug and gene relationship at DGIdb | |||
Expression of PTDSS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTDSS2 | 81490 | 221005_s_at | -0.0366 | 0.9138 | |
| GSE20347 | PTDSS2 | 81490 | 221005_s_at | 0.0182 | 0.8788 | |
| GSE23400 | PTDSS2 | 81490 | 221005_s_at | 0.0687 | 0.1026 | |
| GSE26886 | PTDSS2 | 81490 | 221005_s_at | 0.3729 | 0.0003 | |
| GSE29001 | PTDSS2 | 81490 | 221005_s_at | 0.1116 | 0.7104 | |
| GSE38129 | PTDSS2 | 81490 | 221005_s_at | -0.0729 | 0.4114 | |
| GSE45670 | PTDSS2 | 81490 | 221005_s_at | 0.1391 | 0.1129 | |
| GSE53622 | PTDSS2 | 81490 | 46109 | -0.0748 | 0.3482 | |
| GSE53624 | PTDSS2 | 81490 | 46109 | 0.2082 | 0.0039 | |
| GSE63941 | PTDSS2 | 81490 | 221005_s_at | -0.6628 | 0.0531 | |
| GSE77861 | PTDSS2 | 81490 | 221005_s_at | 0.0525 | 0.7643 | |
| GSE97050 | PTDSS2 | 81490 | A_32_P353798 | 0.0664 | 0.8408 | |
| SRP007169 | PTDSS2 | 81490 | RNAseq | -0.1313 | 0.7639 | |
| SRP064894 | PTDSS2 | 81490 | RNAseq | 0.6139 | 0.0468 | |
| SRP133303 | PTDSS2 | 81490 | RNAseq | -0.0413 | 0.8196 | |
| SRP159526 | PTDSS2 | 81490 | RNAseq | -0.0956 | 0.7726 | |
| SRP193095 | PTDSS2 | 81490 | RNAseq | 0.0992 | 0.4367 | |
| SRP219564 | PTDSS2 | 81490 | RNAseq | 0.4375 | 0.4324 | |
| TCGA | PTDSS2 | 81490 | RNAseq | -0.0966 | 0.1528 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PTDSS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTDSS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTDSS2 | 81490 | 1 | 11 | 18 | |
| GSE20123 | PTDSS2 | 81490 | 1 | 12 | 17 | |
| GSE43470 | PTDSS2 | 81490 | 1 | 10 | 32 | |
| GSE46452 | PTDSS2 | 81490 | 7 | 8 | 44 | |
| GSE47630 | PTDSS2 | 81490 | 4 | 12 | 24 | |
| GSE54993 | PTDSS2 | 81490 | 3 | 2 | 65 | |
| GSE54994 | PTDSS2 | 81490 | 1 | 12 | 40 | |
| GSE60625 | PTDSS2 | 81490 | 0 | 0 | 11 | |
| GSE74703 | PTDSS2 | 81490 | 1 | 8 | 27 | |
| GSE74704 | PTDSS2 | 81490 | 0 | 8 | 12 | |
| TCGA | PTDSS2 | 81490 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 121; Total Number of normals: 340.
Somatic mutations of PTDSS2:
Generating mutation plots.
Highly correlated genes for PTDSS2:
Showing top 20/358 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTDSS2 | COLEC11 | 0.761329 | 3 | 0 | 3 |
| PTDSS2 | POMZP3 | 0.754102 | 3 | 0 | 3 |
| PTDSS2 | PGLS | 0.746074 | 3 | 0 | 3 |
| PTDSS2 | SDF4 | 0.730008 | 3 | 0 | 3 |
| PTDSS2 | IL3RA | 0.726465 | 3 | 0 | 3 |
| PTDSS2 | C19orf54 | 0.721867 | 5 | 0 | 4 |
| PTDSS2 | CDK5RAP2 | 0.719436 | 3 | 0 | 3 |
| PTDSS2 | CASC4 | 0.716751 | 3 | 0 | 3 |
| PTDSS2 | TXNRD1 | 0.716603 | 3 | 0 | 3 |
| PTDSS2 | LINGO1 | 0.702458 | 3 | 0 | 3 |
| PTDSS2 | NGF | 0.701186 | 4 | 0 | 4 |
| PTDSS2 | KEAP1 | 0.700903 | 3 | 0 | 3 |
| PTDSS2 | PCGF2 | 0.695662 | 4 | 0 | 4 |
| PTDSS2 | DGKH | 0.693533 | 3 | 0 | 3 |
| PTDSS2 | NPFF | 0.690972 | 4 | 0 | 3 |
| PTDSS2 | NAA38 | 0.689572 | 3 | 0 | 3 |
| PTDSS2 | ZNF513 | 0.688209 | 4 | 0 | 4 |
| PTDSS2 | TP53I13 | 0.686149 | 4 | 0 | 3 |
| PTDSS2 | DNASE2 | 0.683921 | 3 | 0 | 3 |
| PTDSS2 | C11orf96 | 0.683046 | 3 | 0 | 3 |
For details and further investigation, click here
