| Full name: thymidine phosphorylase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 1890 | HGNC ID: HGNC:3148 | Ensembl Gene: ENSG00000025708 | OMIM ID: 131222 |
| Drug and gene relationship at DGIdb | |||
Expression of TYMP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TYMP | 1890 | 204858_s_at | 1.4084 | 0.1770 | |
| GSE20347 | TYMP | 1890 | 204858_s_at | 0.4624 | 0.1803 | |
| GSE23400 | TYMP | 1890 | 204858_s_at | 0.9381 | 0.0000 | |
| GSE26886 | TYMP | 1890 | 204858_s_at | 0.6717 | 0.2069 | |
| GSE29001 | TYMP | 1890 | 204858_s_at | 0.9377 | 0.0211 | |
| GSE38129 | TYMP | 1890 | 204858_s_at | 0.9553 | 0.0005 | |
| GSE45670 | TYMP | 1890 | 217497_at | 2.1427 | 0.0000 | |
| GSE53622 | TYMP | 1890 | 99955 | 0.8314 | 0.0000 | |
| GSE53624 | TYMP | 1890 | 99955 | 1.2259 | 0.0000 | |
| GSE63941 | TYMP | 1890 | 204858_s_at | 0.8234 | 0.1440 | |
| GSE77861 | TYMP | 1890 | 204858_s_at | 1.0724 | 0.0128 | |
| GSE97050 | TYMP | 1890 | A_33_P3255949 | 0.8275 | 0.0682 | |
| SRP007169 | TYMP | 1890 | RNAseq | 1.1946 | 0.0994 | |
| SRP008496 | TYMP | 1890 | RNAseq | 0.8513 | 0.0656 | |
| SRP064894 | TYMP | 1890 | RNAseq | 2.4225 | 0.0000 | |
| SRP133303 | TYMP | 1890 | RNAseq | 1.6389 | 0.0000 | |
| SRP159526 | TYMP | 1890 | RNAseq | 0.4446 | 0.4128 | |
| SRP193095 | TYMP | 1890 | RNAseq | 1.8699 | 0.0000 | |
| SRP219564 | TYMP | 1890 | RNAseq | 1.9714 | 0.0096 | |
| TCGA | TYMP | 1890 | RNAseq | 0.8563 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by TYMP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TYMP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TYMP | 1890 | 3 | 8 | 19 | |
| GSE20123 | TYMP | 1890 | 3 | 8 | 19 | |
| GSE43470 | TYMP | 1890 | 2 | 8 | 33 | |
| GSE46452 | TYMP | 1890 | 31 | 2 | 26 | |
| GSE47630 | TYMP | 1890 | 9 | 4 | 27 | |
| GSE54993 | TYMP | 1890 | 4 | 6 | 60 | |
| GSE54994 | TYMP | 1890 | 11 | 8 | 34 | |
| GSE60625 | TYMP | 1890 | 5 | 0 | 6 | |
| GSE74703 | TYMP | 1890 | 2 | 6 | 28 | |
| GSE74704 | TYMP | 1890 | 1 | 4 | 15 | |
| TCGA | TYMP | 1890 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of TYMP:
Generating mutation plots.
Highly correlated genes for TYMP:
Showing top 20/529 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TYMP | SCO2 | 0.767744 | 9 | 0 | 9 |
| TYMP | ARAP3 | 0.702577 | 4 | 0 | 3 |
| TYMP | DCBLD1 | 0.699679 | 5 | 0 | 5 |
| TYMP | GPRIN1 | 0.698395 | 5 | 0 | 5 |
| TYMP | SIGLEC10 | 0.685877 | 3 | 0 | 3 |
| TYMP | PTPRH | 0.68486 | 3 | 0 | 3 |
| TYMP | CLSTN3 | 0.665545 | 3 | 0 | 3 |
| TYMP | ZNFX1 | 0.663969 | 7 | 0 | 6 |
| TYMP | PRMT5 | 0.663658 | 3 | 0 | 3 |
| TYMP | TAP1 | 0.662102 | 9 | 0 | 8 |
| TYMP | TLR6 | 0.660663 | 3 | 0 | 3 |
| TYMP | ABTB1 | 0.654281 | 3 | 0 | 3 |
| TYMP | SEC14L4 | 0.654057 | 3 | 0 | 3 |
| TYMP | RFX8 | 0.651199 | 3 | 0 | 3 |
| TYMP | BMP10 | 0.650965 | 3 | 0 | 3 |
| TYMP | EPHB2 | 0.649894 | 6 | 0 | 5 |
| TYMP | SALL4 | 0.646372 | 6 | 0 | 6 |
| TYMP | MYO10 | 0.645408 | 7 | 0 | 5 |
| TYMP | HOXC9 | 0.643699 | 4 | 0 | 4 |
| TYMP | ATAD3C | 0.641087 | 3 | 0 | 3 |
For details and further investigation, click here
