| Full name: transmembrane protein 132E | Alias Symbol: DFNB99 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 124842 | HGNC ID: HGNC:26991 | Ensembl Gene: ENSG00000181291 | OMIM ID: 616178 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM132E:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM132E | 124842 | 243708_at | 0.0917 | 0.6870 | |
| GSE26886 | TMEM132E | 124842 | 243708_at | 0.0833 | 0.5495 | |
| GSE45670 | TMEM132E | 124842 | 243708_at | -0.0846 | 0.3631 | |
| GSE53622 | TMEM132E | 124842 | 40261 | -0.0983 | 0.5440 | |
| GSE53624 | TMEM132E | 124842 | 40261 | -0.3304 | 0.0034 | |
| GSE63941 | TMEM132E | 124842 | 243708_at | 0.2014 | 0.1192 | |
| GSE77861 | TMEM132E | 124842 | 243708_at | -0.0659 | 0.5056 | |
| TCGA | TMEM132E | 124842 | RNAseq | -0.3723 | 0.3611 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM132E expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM132E:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM132E | 124842 | 5 | 1 | 24 | |
| GSE20123 | TMEM132E | 124842 | 5 | 1 | 24 | |
| GSE43470 | TMEM132E | 124842 | 1 | 2 | 40 | |
| GSE46452 | TMEM132E | 124842 | 34 | 0 | 25 | |
| GSE47630 | TMEM132E | 124842 | 7 | 1 | 32 | |
| GSE54993 | TMEM132E | 124842 | 3 | 3 | 64 | |
| GSE54994 | TMEM132E | 124842 | 8 | 6 | 39 | |
| GSE60625 | TMEM132E | 124842 | 4 | 0 | 7 | |
| GSE74703 | TMEM132E | 124842 | 1 | 1 | 34 | |
| GSE74704 | TMEM132E | 124842 | 3 | 1 | 16 | |
| TCGA | TMEM132E | 124842 | 20 | 9 | 67 |
Total number of gains: 91; Total number of losses: 25; Total Number of normals: 372.
Somatic mutations of TMEM132E:
Generating mutation plots.
Highly correlated genes for TMEM132E:
Showing top 20/94 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM132E | AMN | 0.699828 | 3 | 0 | 3 |
| TMEM132E | MMP25 | 0.697712 | 3 | 0 | 3 |
| TMEM132E | PTP4A3 | 0.662709 | 3 | 0 | 3 |
| TMEM132E | HUNK | 0.662149 | 3 | 0 | 3 |
| TMEM132E | ELFN1 | 0.661105 | 3 | 0 | 3 |
| TMEM132E | MAG | 0.659476 | 3 | 0 | 3 |
| TMEM132E | GPR26 | 0.658904 | 4 | 0 | 4 |
| TMEM132E | IGH | 0.657006 | 3 | 0 | 3 |
| TMEM132E | SLC35F3 | 0.655983 | 3 | 0 | 3 |
| TMEM132E | NEUROG3 | 0.655658 | 3 | 0 | 3 |
| TMEM132E | CRIP3 | 0.65235 | 3 | 0 | 3 |
| TMEM132E | AGER | 0.646844 | 3 | 0 | 3 |
| TMEM132E | SIK1 | 0.640612 | 3 | 0 | 3 |
| TMEM132E | LGI2 | 0.636962 | 3 | 0 | 3 |
| TMEM132E | SCN2B | 0.634251 | 3 | 0 | 3 |
| TMEM132E | ADAMTSL5 | 0.626532 | 3 | 0 | 3 |
| TMEM132E | GJB4 | 0.625227 | 3 | 0 | 3 |
| TMEM132E | PURB | 0.624835 | 3 | 0 | 3 |
| TMEM132E | METRN | 0.622141 | 3 | 0 | 3 |
| TMEM132E | FAM131C | 0.616443 | 5 | 0 | 4 |
For details and further investigation, click here
