PWAR5

 

Full name: Prader Willi/Angelman region RNA 5 Alias Symbol: PAR5|PAR-5
Type: non-coding RNA Cytoband: 15q11.2
Entrez ID: 8123 HGNC ID: HGNC:30090 Ensembl Gene: ENSG00000279192 OMIM ID: 600162
Drug and gene relationship at DGIdb

 

Expression of PWAR5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PWAR5 8123 214834_at -0.8405 0.2446
GSE20347 PWAR5 8123 214834_at -0.0851 0.1596
GSE23400 PWAR5 8123 214834_at -0.0296 0.0711
GSE26886 PWAR5 8123 214834_at 0.0763 0.3441
GSE29001 PWAR5 8123 214834_at -0.1135 0.3359
GSE38129 PWAR5 8123 214834_at -0.1116 0.0684
GSE45670 PWAR5 8123 214834_at -0.0687 0.3569
GSE53622 PWAR5 8123 61286 -2.0084 0.0000
GSE53624 PWAR5 8123 61286 -1.5596 0.0000
GSE63941 PWAR5 8123 214834_at -0.2638 0.2292
GSE77861 PWAR5 8123 214834_at -0.0097 0.9112
SRP133303 PWAR5 8123 RNAseq -1.1290 0.0057
SRP159526 PWAR5 8123 RNAseq -0.0152 0.9740
SRP193095 PWAR5 8123 RNAseq -0.5259 0.0291

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by PWAR5 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of PWAR5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PWAR5 8123 2 7 21
GSE20123 PWAR5 8123 2 7 21
GSE43470 PWAR5 8123 3 5 35
GSE46452 PWAR5 8123 3 7 49
GSE47630 PWAR5 8123 8 11 21
GSE54993 PWAR5 8123 4 6 60
GSE54994 PWAR5 8123 7 6 40
GSE60625 PWAR5 8123 4 3 4
GSE74703 PWAR5 8123 3 3 30
GSE74704 PWAR5 8123 1 5 14

Total number of gains: 37; Total number of losses: 60; Total Number of normals: 295.  


 

Somatic mutations of PWAR5:

 

Generating mutation plots.

 

Highly correlated genes for PWAR5:

 

Showing top 20/380 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PWAR5FAM13B0.782711303
PWAR5RAB9B0.769468303
PWAR5SLMAP0.751258303
PWAR5RBM240.749387303
PWAR5LPP0.74935303
PWAR5PRR260.746481303
PWAR5MAMDC20.744765303
PWAR5SHISA30.743004303
PWAR5ANGPTL10.740416303
PWAR5ANKS1B0.734475404
PWAR5ENPP60.733835303
PWAR5MTFR1L0.733436303
PWAR5FOXP10.72785303
PWAR5STMN20.72502303
PWAR5NEXN0.722343303
PWAR5PBX10.717658303
PWAR5PDK40.715362404
PWAR5ANO50.713201404
PWAR5RIC30.712817404
PWAR5TPM10.706402303

For details and further investigation, click here