| Full name: LIM domain containing preferred translocation partner in lipoma | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q27.3-q28 | ||
| Entrez ID: 4026 | HGNC ID: HGNC:6679 | Ensembl Gene: ENSG00000145012 | OMIM ID: 600700 |
| Drug and gene relationship at DGIdb | |||
Expression of LPP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LPP | 4026 | 224811_at | -0.9225 | 0.1840 | |
| GSE20347 | LPP | 4026 | 214902_x_at | 0.4870 | 0.0173 | |
| GSE23400 | LPP | 4026 | 202822_at | -0.4124 | 0.0088 | |
| GSE26886 | LPP | 4026 | 224811_at | 1.0197 | 0.0006 | |
| GSE29001 | LPP | 4026 | 202822_at | 0.0907 | 0.7665 | |
| GSE38129 | LPP | 4026 | 202822_at | -0.4280 | 0.1843 | |
| GSE45670 | LPP | 4026 | 224811_at | -1.4860 | 0.0000 | |
| GSE53622 | LPP | 4026 | 132420 | -1.0526 | 0.0000 | |
| GSE53624 | LPP | 4026 | 132420 | -0.8528 | 0.0000 | |
| GSE63941 | LPP | 4026 | 202822_at | -1.0237 | 0.0049 | |
| GSE77861 | LPP | 4026 | 202822_at | 0.9309 | 0.0077 | |
| GSE97050 | LPP | 4026 | A_33_P3221253 | -1.2299 | 0.1110 | |
| SRP007169 | LPP | 4026 | RNAseq | 1.8512 | 0.0000 | |
| SRP008496 | LPP | 4026 | RNAseq | 2.1907 | 0.0000 | |
| SRP064894 | LPP | 4026 | RNAseq | -0.2510 | 0.3953 | |
| SRP133303 | LPP | 4026 | RNAseq | -0.4832 | 0.0017 | |
| SRP159526 | LPP | 4026 | RNAseq | -0.6533 | 0.0422 | |
| SRP193095 | LPP | 4026 | RNAseq | 0.3691 | 0.0052 | |
| SRP219564 | LPP | 4026 | RNAseq | -0.6595 | 0.4173 | |
| TCGA | LPP | 4026 | RNAseq | -0.2314 | 0.0007 |
Upregulated datasets: 3; Downregulated datasets: 3.
Survival by LPP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LPP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LPP | 4026 | 24 | 0 | 6 | |
| GSE20123 | LPP | 4026 | 24 | 0 | 6 | |
| GSE43470 | LPP | 4026 | 23 | 1 | 19 | |
| GSE46452 | LPP | 4026 | 19 | 1 | 39 | |
| GSE47630 | LPP | 4026 | 27 | 2 | 11 | |
| GSE54993 | LPP | 4026 | 1 | 19 | 50 | |
| GSE54994 | LPP | 4026 | 40 | 0 | 13 | |
| GSE60625 | LPP | 4026 | 0 | 6 | 5 | |
| GSE74703 | LPP | 4026 | 20 | 1 | 15 | |
| GSE74704 | LPP | 4026 | 16 | 0 | 4 | |
| TCGA | LPP | 4026 | 76 | 1 | 19 |
Total number of gains: 270; Total number of losses: 31; Total Number of normals: 187.
Somatic mutations of LPP:
Generating mutation plots.
Highly correlated genes for LPP:
Showing top 20/983 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LPP | PPP1R12B | 0.839435 | 8 | 0 | 7 |
| LPP | PYGM | 0.832145 | 7 | 0 | 7 |
| LPP | ACTBL2 | 0.816459 | 3 | 0 | 3 |
| LPP | PTCHD1 | 0.81552 | 5 | 0 | 5 |
| LPP | NEGR1 | 0.81012 | 6 | 0 | 6 |
| LPP | SORCS1 | 0.808244 | 4 | 0 | 4 |
| LPP | PGR | 0.807258 | 5 | 0 | 5 |
| LPP | MRVI1 | 0.806934 | 7 | 0 | 7 |
| LPP | FLNC | 0.798552 | 9 | 0 | 9 |
| LPP | TLN1 | 0.789062 | 5 | 0 | 5 |
| LPP | AFF3 | 0.781514 | 3 | 0 | 3 |
| LPP | SYNM | 0.778128 | 11 | 0 | 10 |
| LPP | MYOCD | 0.774491 | 7 | 0 | 6 |
| LPP | CACNB2 | 0.770189 | 8 | 0 | 7 |
| LPP | SMTN | 0.768009 | 9 | 0 | 8 |
| LPP | LMOD1 | 0.767008 | 11 | 0 | 10 |
| LPP | PLA2G5 | 0.766604 | 6 | 0 | 6 |
| LPP | SLITRK3 | 0.765639 | 8 | 0 | 7 |
| LPP | RBPMS2 | 0.765073 | 7 | 0 | 7 |
| LPP | TPM1 | 0.764588 | 12 | 0 | 11 |
For details and further investigation, click here
