PWRN2

 

Full name: Prader-Willi region non-protein coding RNA 2 Alias Symbol: NCRNA00199
Type: non-coding RNA Cytoband: 15q11.2
Entrez ID: 791115 HGNC ID: HGNC:33236 Ensembl Gene: ENSG00000260551 OMIM ID: 611217
Drug and gene relationship at DGIdb

 

Expression of PWRN2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PWRN2 791115 1568663_a_at -0.0710 0.7296
GSE26886 PWRN2 791115 1568663_a_at 0.0879 0.4724
GSE45670 PWRN2 791115 1568663_a_at 0.0353 0.6471
GSE53622 PWRN2 791115 7571 0.1048 0.4885
GSE53624 PWRN2 791115 7571 0.3583 0.0008
GSE63941 PWRN2 791115 1568663_a_at 0.0960 0.5770
GSE77861 PWRN2 791115 1568663_a_at -0.0328 0.8018
TCGA PWRN2 791115 RNAseq 1.6176 0.4608

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by PWRN2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PWRN2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PWRN2 791115 2 7 21
GSE20123 PWRN2 791115 2 7 21
GSE43470 PWRN2 791115 3 5 35
GSE46452 PWRN2 791115 3 7 49
GSE47630 PWRN2 791115 8 11 21
GSE54993 PWRN2 791115 4 6 60
GSE54994 PWRN2 791115 7 6 40
GSE60625 PWRN2 791115 4 3 4
GSE74703 PWRN2 791115 3 3 30
GSE74704 PWRN2 791115 1 5 14
TCGA PWRN2 791115 17 20 59

Total number of gains: 54; Total number of losses: 80; Total Number of normals: 354.  


 

Somatic mutations of PWRN2:

 

Generating mutation plots.

 

Highly correlated genes for PWRN2:

 

Showing top 20/28 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PWRN2CNPY10.660961303
PWRN2LINC008570.640944303
PWRN2HCRT0.638886303
PWRN2FOXD4L50.630889303
PWRN2C1orf1940.61448303
PWRN2SPAM10.612019403
PWRN2SIGLEC60.598149403
PWRN2CCDC380.581369303
PWRN2LINC001630.578227403
PWRN2KCNB20.576169303
PWRN2GFRA20.574573403
PWRN2TAC30.572259403
PWRN2TXNDC20.569384403
PWRN2MYL10.56552403
PWRN2KCNJ10.559904403
PWRN2SLC38A30.558244303
PWRN2MS4A6E0.554086303
PWRN2TMEM920.551616403
PWRN2TMEM2070.549487403
PWRN2SPINT30.544247603

For details and further investigation, click here