| Full name: archaelysin family metallopeptidase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q24.2 | ||
| Entrez ID: 51321 | HGNC ID: HGNC:28041 | Ensembl Gene: ENSG00000196704 | OMIM ID: 615169 |
| Drug and gene relationship at DGIdb | |||
Expression of AMZ2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMZ2 | 51321 | 218167_at | 0.2268 | 0.5458 | |
| GSE20347 | AMZ2 | 51321 | 218167_at | 0.5518 | 0.0018 | |
| GSE23400 | AMZ2 | 51321 | 218167_at | 0.5900 | 0.0000 | |
| GSE26886 | AMZ2 | 51321 | 218167_at | -0.6068 | 0.0618 | |
| GSE29001 | AMZ2 | 51321 | 218167_at | 0.5086 | 0.1168 | |
| GSE38129 | AMZ2 | 51321 | 218167_at | 0.4719 | 0.0004 | |
| GSE45670 | AMZ2 | 51321 | 218167_at | 0.2480 | 0.1207 | |
| GSE53622 | AMZ2 | 51321 | 52571 | 0.3257 | 0.0000 | |
| GSE53624 | AMZ2 | 51321 | 52571 | 0.4706 | 0.0000 | |
| GSE63941 | AMZ2 | 51321 | 218167_at | 0.1419 | 0.7432 | |
| GSE77861 | AMZ2 | 51321 | 218167_at | 0.6515 | 0.0041 | |
| GSE97050 | AMZ2 | 51321 | A_23_P15564 | 0.0160 | 0.9685 | |
| SRP007169 | AMZ2 | 51321 | RNAseq | 0.2671 | 0.4589 | |
| SRP008496 | AMZ2 | 51321 | RNAseq | 0.1875 | 0.3252 | |
| SRP064894 | AMZ2 | 51321 | RNAseq | 0.5987 | 0.0007 | |
| SRP133303 | AMZ2 | 51321 | RNAseq | 0.7011 | 0.0001 | |
| SRP159526 | AMZ2 | 51321 | RNAseq | 0.6031 | 0.0004 | |
| SRP193095 | AMZ2 | 51321 | RNAseq | 0.1585 | 0.1339 | |
| SRP219564 | AMZ2 | 51321 | RNAseq | 0.1658 | 0.6439 | |
| TCGA | AMZ2 | 51321 | RNAseq | 0.1460 | 0.0034 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AMZ2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMZ2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMZ2 | 51321 | 3 | 3 | 24 | |
| GSE20123 | AMZ2 | 51321 | 3 | 3 | 24 | |
| GSE43470 | AMZ2 | 51321 | 4 | 0 | 39 | |
| GSE46452 | AMZ2 | 51321 | 31 | 1 | 27 | |
| GSE47630 | AMZ2 | 51321 | 7 | 1 | 32 | |
| GSE54993 | AMZ2 | 51321 | 2 | 5 | 63 | |
| GSE54994 | AMZ2 | 51321 | 9 | 4 | 40 | |
| GSE60625 | AMZ2 | 51321 | 4 | 2 | 5 | |
| GSE74703 | AMZ2 | 51321 | 4 | 0 | 32 | |
| GSE74704 | AMZ2 | 51321 | 3 | 2 | 15 | |
| TCGA | AMZ2 | 51321 | 28 | 8 | 60 |
Total number of gains: 98; Total number of losses: 29; Total Number of normals: 361.
Somatic mutations of AMZ2:
Generating mutation plots.
Highly correlated genes for AMZ2:
Showing top 20/1092 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMZ2 | ATP6V1H | 0.776331 | 3 | 0 | 3 |
| AMZ2 | C6orf62 | 0.773296 | 3 | 0 | 3 |
| AMZ2 | EPAS1 | 0.763318 | 3 | 0 | 3 |
| AMZ2 | SNAPIN | 0.750912 | 4 | 0 | 4 |
| AMZ2 | LRRC58 | 0.747455 | 3 | 0 | 3 |
| AMZ2 | SNX18 | 0.742033 | 3 | 0 | 3 |
| AMZ2 | RALGAPB | 0.737981 | 3 | 0 | 3 |
| AMZ2 | LYST | 0.732512 | 3 | 0 | 3 |
| AMZ2 | NIPA1 | 0.731756 | 4 | 0 | 4 |
| AMZ2 | UBR1 | 0.723726 | 3 | 0 | 3 |
| AMZ2 | ELOF1 | 0.705112 | 3 | 0 | 3 |
| AMZ2 | PRCC | 0.704511 | 7 | 0 | 7 |
| AMZ2 | RABEP1 | 0.704434 | 3 | 0 | 3 |
| AMZ2 | PIGU | 0.702694 | 3 | 0 | 3 |
| AMZ2 | NDUFA10 | 0.702526 | 3 | 0 | 3 |
| AMZ2 | SIRT1 | 0.698314 | 3 | 0 | 3 |
| AMZ2 | KLHL5 | 0.695651 | 5 | 0 | 3 |
| AMZ2 | FADS1 | 0.692342 | 3 | 0 | 3 |
| AMZ2 | NFKB1 | 0.690371 | 4 | 0 | 3 |
| AMZ2 | QSOX2 | 0.689306 | 3 | 0 | 3 |
For details and further investigation, click here
