DAP3

 

Full name: death associated protein 3 Alias Symbol: MRPS29|DAP-3|MRP-S29|bMRP-10|MGC126058|MGC126059|DKFZp686G12159
Type: protein-coding gene Cytoband: 1q22
Entrez ID: 7818 HGNC ID: HGNC:2673 Ensembl Gene: ENSG00000132676 OMIM ID: 602074
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of DAP3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DAP3 7818 208822_s_at 0.5748 0.0587
GSE20347 DAP3 7818 208822_s_at 0.5615 0.0000
GSE23400 DAP3 7818 208822_s_at 0.5945 0.0000
GSE26886 DAP3 7818 208822_s_at 0.4738 0.0052
GSE29001 DAP3 7818 208822_s_at 0.5056 0.0151
GSE38129 DAP3 7818 208822_s_at 0.7040 0.0000
GSE45670 DAP3 7818 208822_s_at 0.3397 0.0123
GSE53622 DAP3 7818 52280 0.4227 0.0000
GSE53624 DAP3 7818 52280 0.4410 0.0000
GSE63941 DAP3 7818 208822_s_at 0.4425 0.1767
GSE77861 DAP3 7818 208822_s_at 0.7694 0.0028
GSE97050 DAP3 7818 A_23_P63067 0.0518 0.9297
SRP007169 DAP3 7818 RNAseq -0.0878 0.8190
SRP008496 DAP3 7818 RNAseq 0.3361 0.1367
SRP064894 DAP3 7818 RNAseq 0.1843 0.1611
SRP133303 DAP3 7818 RNAseq 0.4171 0.0000
SRP159526 DAP3 7818 RNAseq 0.7695 0.0002
SRP193095 DAP3 7818 RNAseq 0.1988 0.0133
SRP219564 DAP3 7818 RNAseq 0.3224 0.3627
TCGA DAP3 7818 RNAseq 0.0931 0.0487

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by DAP3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DAP3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DAP3 7818 14 0 16
GSE20123 DAP3 7818 13 0 17
GSE43470 DAP3 7818 7 2 34
GSE46452 DAP3 7818 2 1 56
GSE47630 DAP3 7818 14 0 26
GSE54993 DAP3 7818 0 5 65
GSE54994 DAP3 7818 16 0 37
GSE60625 DAP3 7818 0 0 11
GSE74703 DAP3 7818 7 2 27
GSE74704 DAP3 7818 6 0 14
TCGA DAP3 7818 38 3 55

Total number of gains: 117; Total number of losses: 13; Total Number of normals: 358.  

 

Somatic mutations of DAP3:

 

Generating mutation plots.

 

Highly correlated genes for DAP3:

 

Showing top 20/1836 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DAP3TBRG40.783091303
DAP3PFDN20.77495212012
DAP3GNPNAT10.760591303
DAP3CPSF60.75170411011
DAP3ILF20.73935912011
DAP3SAMD10.735511404
DAP3PSMB40.73386612011
DAP3FLAD10.73178511010
DAP3TOP2A0.72578310010
DAP3C1orf1120.72335710010
DAP3EMG10.718434707
DAP3CCDC1270.717896303
DAP3MTHFD20.71451911011
DAP3U2SURP0.714294908
DAP3MSTO10.714113707
DAP3TTL0.713577707
DAP3DNAJC20.711512011
DAP3TMCO60.710347303
DAP3UBE2C0.7098710010
DAP3EBNA1BP20.707736303

For details and further investigation, click here