ABHD15

 

Full name: abhydrolase domain containing 15 Alias Symbol: 
Type: protein-coding gene Cytoband: 17q11.2
Entrez ID: 116236 HGNC ID: HGNC:26971 Ensembl Gene: ENSG00000168792 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ABHD15:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ABHD15 116236 226796_at 0.1065 0.8475
GSE26886 ABHD15 116236 226796_at 0.5383 0.0286
GSE45670 ABHD15 116236 226796_at 0.3664 0.1273
GSE53622 ABHD15 116236 45889 0.5443 0.0000
GSE53624 ABHD15 116236 45889 0.3167 0.0072
GSE63941 ABHD15 116236 226796_at -0.8222 0.1339
GSE77861 ABHD15 116236 226796_at 0.2324 0.1426
GSE97050 ABHD15 116236 A_33_P3216913 0.3664 0.1606
SRP007169 ABHD15 116236 RNAseq 0.9374 0.0255
SRP008496 ABHD15 116236 RNAseq 1.1384 0.0010
SRP064894 ABHD15 116236 RNAseq 0.8061 0.0000
SRP133303 ABHD15 116236 RNAseq 0.2974 0.0399
SRP159526 ABHD15 116236 RNAseq 0.4787 0.2775
SRP193095 ABHD15 116236 RNAseq 0.2830 0.0407
SRP219564 ABHD15 116236 RNAseq 0.3337 0.3085
TCGA ABHD15 116236 RNAseq -0.0084 0.9064

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by ABHD15 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ABHD15:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ABHD15 116236 7 2 21
GSE20123 ABHD15 116236 8 2 20
GSE43470 ABHD15 116236 0 1 42
GSE46452 ABHD15 116236 33 1 25
GSE47630 ABHD15 116236 7 1 32
GSE54993 ABHD15 116236 2 3 65
GSE54994 ABHD15 116236 7 5 41
GSE60625 ABHD15 116236 4 0 7
GSE74703 ABHD15 116236 0 1 35
GSE74704 ABHD15 116236 5 2 13
TCGA ABHD15 116236 22 9 65

Total number of gains: 95; Total number of losses: 27; Total Number of normals: 366.  


 

Somatic mutations of ABHD15:

 

Generating mutation plots.

 

Highly correlated genes for ABHD15:

 

Showing top 20/545 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ABHD15PSPC10.713006404
ABHD15LIMK10.706559303
ABHD15NOTCH30.701929303
ABHD15MAN1A10.698235303
ABHD15SSH10.695297303
ABHD15RABEP10.689473303
ABHD15SAMM500.68611303
ABHD15WDR890.685533303
ABHD15DPYSL20.680608303
ABHD15TMEM1070.677597403
ABHD15NAGLU0.673606404
ABHD15SH3RF30.672243403
ABHD15GLIPR10.671216303
ABHD15TUBGCP30.670252303
ABHD15RNF60.670246303
ABHD15LPGAT10.668975303
ABHD15LYN0.668902504
ABHD15TLR10.66852503
ABHD15ZDHHC240.666094303
ABHD15STX30.663345303

For details and further investigation, click here