| Full name: TATA-box binding protein associated factor 10 | Alias Symbol: TAFII30 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 6881 | HGNC ID: HGNC:11543 | Ensembl Gene: ENSG00000166337 | OMIM ID: 600475 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAF10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF10 | 6881 | 200055_at | -0.0122 | 0.9826 | |
| GSE20347 | TAF10 | 6881 | 200055_at | -0.4591 | 0.0010 | |
| GSE23400 | TAF10 | 6881 | 200055_at | 0.0576 | 0.3563 | |
| GSE26886 | TAF10 | 6881 | 200055_at | 0.7226 | 0.0004 | |
| GSE29001 | TAF10 | 6881 | 200055_at | -0.4056 | 0.0598 | |
| GSE38129 | TAF10 | 6881 | 200055_at | -0.2262 | 0.0878 | |
| GSE45670 | TAF10 | 6881 | 200055_at | 0.0784 | 0.5408 | |
| GSE53622 | TAF10 | 6881 | 35786 | -0.0540 | 0.2946 | |
| GSE53624 | TAF10 | 6881 | 35786 | -0.0002 | 0.9966 | |
| GSE63941 | TAF10 | 6881 | 200055_at | 0.0217 | 0.9609 | |
| GSE77861 | TAF10 | 6881 | 200055_at | -0.1781 | 0.6955 | |
| GSE97050 | TAF10 | 6881 | A_33_P3257232 | 0.0627 | 0.7575 | |
| SRP007169 | TAF10 | 6881 | RNAseq | -0.6922 | 0.0395 | |
| SRP008496 | TAF10 | 6881 | RNAseq | -0.5489 | 0.0018 | |
| SRP064894 | TAF10 | 6881 | RNAseq | -0.0601 | 0.7580 | |
| SRP133303 | TAF10 | 6881 | RNAseq | -0.2524 | 0.0327 | |
| SRP159526 | TAF10 | 6881 | RNAseq | -0.3828 | 0.1193 | |
| SRP193095 | TAF10 | 6881 | RNAseq | -0.2862 | 0.0029 | |
| SRP219564 | TAF10 | 6881 | RNAseq | -0.0542 | 0.8078 | |
| TCGA | TAF10 | 6881 | RNAseq | 0.0562 | 0.3901 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAF10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF10 | 6881 | 1 | 11 | 18 | |
| GSE20123 | TAF10 | 6881 | 1 | 11 | 18 | |
| GSE43470 | TAF10 | 6881 | 1 | 8 | 34 | |
| GSE46452 | TAF10 | 6881 | 7 | 8 | 44 | |
| GSE47630 | TAF10 | 6881 | 2 | 12 | 26 | |
| GSE54993 | TAF10 | 6881 | 3 | 1 | 66 | |
| GSE54994 | TAF10 | 6881 | 2 | 12 | 39 | |
| GSE60625 | TAF10 | 6881 | 0 | 0 | 11 | |
| GSE74703 | TAF10 | 6881 | 1 | 6 | 29 | |
| GSE74704 | TAF10 | 6881 | 0 | 8 | 12 | |
| TCGA | TAF10 | 6881 | 9 | 38 | 49 |
Total number of gains: 27; Total number of losses: 115; Total Number of normals: 346.
Somatic mutations of TAF10:
Generating mutation plots.
Highly correlated genes for TAF10:
Showing top 20/255 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF10 | ZNF408 | 0.810145 | 3 | 0 | 3 |
| TAF10 | LPCAT3 | 0.800871 | 3 | 0 | 3 |
| TAF10 | MRPL9 | 0.774714 | 3 | 0 | 3 |
| TAF10 | PNN | 0.772322 | 3 | 0 | 3 |
| TAF10 | RABEP2 | 0.771219 | 3 | 0 | 3 |
| TAF10 | SLCO3A1 | 0.758636 | 3 | 0 | 3 |
| TAF10 | C1orf35 | 0.746759 | 3 | 0 | 3 |
| TAF10 | TP53I11 | 0.744104 | 3 | 0 | 3 |
| TAF10 | MRPL51 | 0.741346 | 3 | 0 | 3 |
| TAF10 | LGALS8 | 0.739166 | 3 | 0 | 3 |
| TAF10 | LRRC23 | 0.738924 | 3 | 0 | 3 |
| TAF10 | ACY1 | 0.736779 | 3 | 0 | 3 |
| TAF10 | UBA1 | 0.734977 | 3 | 0 | 3 |
| TAF10 | ALG10 | 0.727137 | 3 | 0 | 3 |
| TAF10 | VRK2 | 0.72447 | 3 | 0 | 3 |
| TAF10 | DEXI | 0.720713 | 3 | 0 | 3 |
| TAF10 | RNFT2 | 0.718286 | 4 | 0 | 4 |
| TAF10 | ZDHHC5 | 0.716451 | 4 | 0 | 3 |
| TAF10 | SNAPC2 | 0.71277 | 3 | 0 | 3 |
| TAF10 | PSEN1 | 0.711524 | 3 | 0 | 3 |
For details and further investigation, click here
